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Amicline Plus Tablet
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Amicline Plus Tablet

Manufactured byFRANCO INDIAN PHARMACEUTICALS PVT LTD
ContainsDiloxanide Furoate (375 mg) + Ornidazole (250 mg)
Description
Amicline Plus Tablet is used for the treatment of intestinal amebiasis and extraintestinal forms of amebiasis which is caused by Entamoeba histolytica. It is also used for the treatment of giardiasis, an intestinal infection caused by Giardia lambia strains of protozoa.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Amicline Plus Tablet

  • Severe skin rash and hives
  • Excessive gas in stomach
  • Nausea and vomiting
  • Abdominal pain and cramps
  • Loss of appetite
  • Diarrhea
  • Headache
  • Dry mouth
  • Unusual tiredness and weakness
  • Chills
  • Difficulty in breathing
  • Change in taste/ Metallic taste
  • Dizziness

Uses of Amicline Plus Tablet

What is it prescribed for?

  • Intestinal amoebiasis
  • Extra-intestinal amoebiasis
  • Asymptomatic cyst passers
  • Giardiasis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of adverse effects. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ornidazole, diloxanide, or any other inactive ingredient present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Completion of the treatment course

It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so may result in drug resistance, making the treatment of subsequent infections very difficult.

Multiple sclerosis

This medicine should be used with extreme caution in patients suffering from this neurodegenerative disorder of the brain. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Epilepsy

This medicine should be used with caution in patients suffering from epilepsy or other convulsion disorders. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney/Liver impairment

This medicine should be used with caution in patients having an impairment of the kidney/liver function. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or Operating machinery

This medicine may cause symptoms such as weakness, drowsiness, sleepiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Use in elderly

This medicine should be used with caution and monitoring in elderly patients since the risk of adverse effects is significantly high. Replacement with a suitable alternative may be necessary for some patients based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of adverse effects. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Vecuronium

Warfarin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by your doctor. Do not consume in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the growth of protozoa by interfering with protein formation process leading to cell lysis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antiprotozoals, Anthelmintics

Schedule

Schedule H

[Internet]. Francoindian.com. 2019 [cited 21 May 2019]. Available from:

http://www.francoindian.com/products/amicline-plus.htm

Diloxanide - DrugBank [Internet]. Drugbank.ca. 2019 [cited 21 May 2019]. Available from:

https://www.drugbank.ca/drugs/DB08792

Ornidazole - DrugBank [Internet]. Drugbank.ca. 2019 [cited 21 May 2019]. Available from:

https://www.drugbank.ca/drugs/DB13026
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Information on this page was last updated on 1 Aug 2019

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