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Amantrel 100 mg Capsule

Manufactured byCipla Ltd.
ContainsAmantadine
Description

Amantrel 100 mg Capsule is an antiviral medicine used in the treatment of infections caused by the influenza A virus. It is also used alone or in combination with other medicines to treat Parkinson's disease and Parkinson-like symptoms. These may include shakiness, stiffness, and slowness of movement. This medicine should be used with caution in patients with a known history of seizure disorders due to the increased risk of recurrent seizures.

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Side effects

Major & minor side effects for Amantrel 100 mg Capsule

  • Blurred vision
  • Confusion
  • Fainting
  • Pain and swelling of joint
  • Headache
  • Irritability
  • Loss of appetite
  • Nausea
  • Trouble sleeping

Uses of Amantrel 100 mg Capsule

What is it prescribed for?

  • Influenza Prophylaxis
  • Influenza A infections
  • Parkinson's disease
  • Extrapyramidal Reaction
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 48 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The time until which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to amantadine or any other inactive ingredient present along with it.

Narrow angle glaucoma

This medicine is not recommended for use in patients with a known history of untreated narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
General warnings

Compulsive Behaviors

This medicine should be used with caution due to the increased risk of impulsive or compulsive behaviors. These may include an intense urge to gamble, binge eat, or spend money. Close monitoring of the patients for any change in behavior and mood is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor on priority. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hallucinations

Amantrel 100 mg Capsule should be used with caution due to an increased risk of severe side effects such as hallucinations, psychotic episodes, and confusion. This risk is especially higher in the elderly patients. Close monitoring of patients for any changes in mood and behavior is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor on priority. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery while taking this medicine.

Falling asleep during daily activities

Amantrel 100 mg Capsule should be used with caution due to the increased risk of side effects such as dizziness, fainting, and drowsiness. This may cause you to fall asleep during your day-to-day activities. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery while taking this medicine.

Hepatic disease

Amantrel 100 mg Capsule should be used with caution in patients with a history of liver disease and active liver disease due to the increased risk of severe adverse effects. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Dicyclomine

Doxepin

Loxapine

Azatadine

Disease interactions

Renal impairment

Amantrel 100 mg Capsule should be used with extreme caution in patients with renal diseases due to the increased risk of severe adverse effects. Renal function should be assessed before initiating the treatment. Appropriate dose adjustments should be done under your doctor's supervision.

Depression

This medicine should be used with extreme caution in patients with a known history of depression due to the increased risk of worsening of the patient's condition. Patients should be monitored closely for any changes in behavior and mood. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Psychosis

Amantrel 100 mg Capsule is not recommended for use in patients with a known history of psychotic disorders due to the increased risk of worsening of the patient's condition. Close monitoring of the patients for any changes in behavior or mood may be necessary based on the clinical condition. Replacement with a suitable alternative may be required in some cases.

Hypotension

Amantrel 100 mg Capsule may increase the risk of orthostatic hypotension. This risk is especially higher in patients receiving high blood pressure medicines and elderly patients. Close monitoring of blood pressure may be necessary for such patients. Patients are advised to get up slowly from a sitting or a lying position to avoid fainting and falling. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Seizures

This medicine should be used with extreme caution in patients with a known history of seizure disorder due to the increased risk of recurrent seizures. Consult the doctor immediately in case of any unusual side effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Amantrel 100 mg Capsule exactly as instructed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that proper hygiene measures are adopted. Complete the course of treatment to prevent the spread of the infection. Close monitoring of kidney function may be necessary during treatment with this medicine. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amantrel 100 mg Capsule blocks the influenza A virus from multiplying and stops the spread of the infection. It also increases the concentration of dopamine in the brain, a natural substance which helps in relieving the symptoms of Parkinson's disease.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Adamantane antivirals, Dopaminergic Antiparkinsonism agents

Schedule

Schedule H

Amantadine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 29 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00915

Amantadine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 29 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682064.html

DailyMed: Amantadine capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 29 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4157d9a7-a53f-4dde-b051-fe3e9a674913

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 29 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database
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Information on this page was last updated on 29 Jan 2020

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