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Amace-BP Tablet
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Amace-BP Tablet

Manufactured bySYSTOPIC LABORATORIES PVT LTD
ContainsAmlodipine (5 mg) + Benazepril (10 mg)
Description
Amace-BP Tablet is a combination medicine used for the treatment of high blood pressure. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect. This medicine is not recommended for use in patients below 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Amace-BP Tablet

  • Increased potassium levels
  • Blurred vision
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Skin rash
  • Low blood pressure (hypotension)
  • Cough
  • Increased heartbeat
  • Dizziness
  • Shortness of breath
  • Chills and fever
  • Stomach pain
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Heartburn
  • Acid or sour stomach

Uses of Amace-BP Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 to 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to amlodipine, benazepril, other ACE inhibitors, or any other inactive ingredients present in the formulation.

Angioedema

This medicine is not recommended for use in patients with a known history of angiotensin converting enzyme inhibitors induced angioedema or hereditary angioedema due to the increased risk of worsening of the patient's condition.

Aliskiren

Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

Use of this medicine may cause hypotension, especially when used in combination with other high blood pressure medicines such as diuretics. Regular monitoring of blood pressure is recommended during treatment with this medicine. Appropriate dose adjustments should be done based on the clinical condition.

Aliskiren

This medicine is not recommended for use in combination with aliskiren due to the increased risk of serious side effects. This risk is especially higher in diabetic patients. Replacement with a suitable alternative should be done under your doctor's supervision.

Hyperkalemia

Use of this medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.

Coronary artery diseases

This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

Use of this medicine may rarely cause liver injuries such as jaundice or hepatitis. Close monitoring of liver function is recommended during treatment with this medicine. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in Children

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Driving and Operating machinery

Use of this medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Allopurinol

Carbamazepine

Itraconazole

Corticosteroids

Rifampicin

Aliskiren

Insulin

Diclofenac

Valsartan

Candesartan

Sacubitril

Disease interactions

Bone marrow suppression

This medicine should be used with caution in patients with bone marrow suppression due to the increased risk of worsening of the patient's condition. Close monitoring of complete blood counts is necessary for such patients. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Regular monitoring of the kidney function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
It is recommended to avoid a high potassium diet during treatment with this medicine due to the increased risk of serious adverse effects. Your doctor/dietitian will suggest an appropriate diet for you to avoid high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine relaxes the heart muscles and the blood vessels. Benazepril relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

ACE inhibitors with calcium channel blocking agents, Antihypertensive combinations

Schedule

Schedule H

DailyMed - Amlodipine and benazepril hydrochloride capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 3 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fe4734a2-6219-8bf5-9c3a-d392910db4dc

Amlodipine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 7 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692044.html

Benazepril: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692011.html

Benazepril - DrugBank [Internet]. Drugbank.ca. 2017 [cited 10 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00542
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Information on this page was last updated on 2 May 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.