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Aluvia Tablet

Manufactured byABBOTT HEALTHCARE PVT LTD
ContainsLopinavir (200 mg) + Ritonavir (50 mg)
Description
Aluvia Tablet is a combination of Lopinavir and Ritonavir. It is an antiviral medicine used for the treatment of human immunodeficiency virus (HIV) infection (a condition that occurs when the virus attacks the immune system and interferes with your body's ability to fight infections or diseases). Aluvia Tablet will not cure HIV infection, but it will delay the progression of a chronic, potentially life-threatening condition known as acquired immunodeficiency syndrome (AIDS) and other HIV-related conditions. This medicine works by preventing the virus from multiplying. Aluvia Tablet shows some side effects like nausea, vomiting, stomach pain, diarrhoea, headache, increase in cholesterol and fats level, etc. Consult your doctor if they bother you for a longer time or worsen. Do not take this medicine if you are allergic to it. Aluvia Tablet may be taken with food or without food. Take it in the dose and duration prescribed by your doctor. Avoid taking more than the recommended dose as it may increase the risk of side effects. Take it every day at the same time to maintain a consistent level of this medicine in your blood. Avoid discontinuing this medication without consulting your doctor, as it may worsen your condition. Aluvia Tablet may not be suitable for everyone. It is not recommended for use in children less than two years of age. Inform your doctor if you have heart, liver, or kidney problems or any other health conditions. Also, inform your doctor about all your ongoing medications to avoid undesired effects. Aluvia Tablet is unsafe for use during pregnancy. Consult your doctor if you are breastfeeding. If you have an HIV infection, it is not recommended to breastfeed, as the Human immunodeficiency virus (HIV) may transfer to the baby through breastmilk.

Side effects

Major & minor side effects for Aluvia Tablet

  • Diarrhoea
  • Vomiting
  • Nausea
  • Stomach pain
  • Constipation
  • Indigestion
  • Rash
  • Itching
  • Blurred vision
  • Fever
  • Dizziness
  • Redness of the skin especially on the face and neck
  • Headache
  • Sweating
  • Weight loss
  • Confusion
  • Sleepiness or unusual drowsiness
  • Mood or mental changes
  • Abnormal dreams
  • Increased cholesterol and triglycerides

Uses of Aluvia Tablet

What is it prescribed for?

  • HIV infection
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Aluvia Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Aluvia Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Aluvia Tablet.
  • Can this medicine be taken during pregnancy?
    Aluvia Tablet may be unsafe for use during pregnancy as animal studies indicate that it may harm the developing foetus. However, there are no human data available. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Aluvia Tablet is not recommended for use while breastfeeding. Also, women with HIV infection are not recommended to breastfeed as the Human immunodeficiency virus (HIV) can be passed to the baby through breastmilk.

Allergy

Avoid taking Aluvia Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe liver impairment

Aluvia Tablet is not recommended for use if you have severe liver problems, as this medicine may cause liver toxicity and further worsen your condition. It should be used with extreme caution if you have mild to moderate liver problems.
Warnings for special population

Pregnancy

Aluvia Tablet may be unsafe for use during pregnancy as animal studies indicate that it may harm the developing foetus. However, there are no human data available. Hence, consult your doctor if you are pregnant.

Breast-feeding

Aluvia Tablet is not recommended for use while breastfeeding. Also, women with HIV infection are not recommended to breastfeed as the Human immunodeficiency virus (HIV) can be passed to the baby through breastmilk.
General warnings

Fat redistribution

Aluvia Tablet should be used with caution as it may cause fat gain or fat loss in the body. It may result in central obesity, buffalo hump (excess fat behind the neck), peripheral wasting (difficulty in moving an arm or leg or making any movement), facial wasting (fat loss in the cheeks and temples), breast enlargement, and cushingoid appearance (extra fat build up on the sides of the face and weight gain). Consult your doctor if you have any concerns.

Pancreatitis

Pancreatitis refers to the swelling of the pancreas, a gland that produces chemical substances which help in digestion and regulation of blood sugar. Aluvia Tablet should be used with caution as it may cause pancreatitis or worsen the existing condition if you have pancreatitis.

Use in children

Aluvia Tablet is not recommended for use in children below two years of age due to the lack of safety and efficacy data.

Immune reconstitution syndrome

Changes in your immune system can occur when you start taking Aluvia Tablet. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. It may cause an exaggerated response making the symptoms of infection worse. Inform your doctor if you develop any new symptoms after starting treatment with Aluvia Tablet.

Osteonecrosis

Aluvia Tablet should be used with caution as it may rarely cause osteonecrosis (the death of bone cells due to a lack of blood supply). Consult your doctor if you experience joint aches and pain, joint stiffness, or difficulty in movement

Increase in cholesterol and fats levels

Aluvia Tablet should be used with caution as it may cause an increase in cholesterol and fats levels in the blood. Your doctor may suggest tests to periodically monitor your lipid (fats) levels in the blood while you are taking this medicine.

Missed Dose

Take the missed dose of Aluvia Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Contact your doctor in case of an overdose of Aluvia Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Erythromycin

Fluoxetine

Midazolam

Rosuvastatin

Alprazolam

Atorvastatin

Acarbose

abemaciclib

Disease interactions

Diabetes Mellitus

Diabetes is a condition in which your blood sugar levels are increased. Aluvia Tablet should be used with caution if you have diabetes as it may alter your blood sugar levels. Monitor your blood sugar levels regularly while you are taking this medicine.

Cardiovascular disease

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Aluvia Tablet may cause QT prolongation hence, it should be used with caution if you have heart problems.

Bleeding disorders

Haemophilia is an inherited bleeding disorder in which the blood does not clot properly. Aluvia Tablet should be used with caution if you have haemophilia due to the increased risk of excessive bleeding.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Aluvia Tablet exactly as instructed by your doctor. Do not take in larger or smaller quantities than recommended. Your doctor may suggest tests to monitor your liver function and lipid (fats) levels during treatment with this medicine. Taking Aluvia Tablet will not prevent the transmission of HIV to others. Hence, avoid having unprotected sexual intercourse or sharing razors or toothbrushes.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Aluvia Tablet works by stopping the human immunodeficiency virus (HIV) from multiplying. This helps in delaying the progression of acquired immunodeficiency syndrome (AIDS) and other HIV-related conditions.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antiviral combinations

Schedule

Schedule H

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Medicines.org.uk. 2022. Kaletra 200 mg/50 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 March 2022].

https://www.medicines.org.uk/emc/product/221/smpc#>

Drugs, H., 2022. Lopinavir and Ritonavir: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 1 March 2022].

https://medlineplus.gov/druginfo/meds/a602015.html>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 1 March 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021906lbl.pdf>
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Information on this page was last updated on 2 Mar 2022

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