All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Osteonecrosis of the jaw (ONJ)severe
This medicine should be used with caution in patients undergoing invasive dental procedures due to the increased risk of osteonecrosis of the jaw (ONJ). Therapy with the medicine may need to be discontinued based on the clinical condition of the patient.
Alendronate is not recommended for use in patients with creatinine clearance less than 35 ml/min due to the increased risk of acute renal failure. Close monitoring of kidney function is necessary during treatment with this medicine.
Alendronate is not recommended for treating osteoporosis in patients with decreased calcium levels (hypocalcemia). Calcium and vitamin D levels should be checked before starting therapy with this medicine. It is also important to continue appropriate supplementation of calcium and vitamin D during treatment with this medicine.
Upper gastrointestinal mucosal irritationsevere
Alendronate may cause upper gastrointestinal mucosal irritation and increase the risk of gastric ulcers and bleeding. It is advised to take the tablet along with a full glass of water and stand or sit upright for at least 30 minutes after the dose to reduce the chances of these side effects. Therapy should be discontinued if the patient experiences any difficulty in swallowing or persistent abdominal pain. Report any such symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Caution is advised while using this medicine in patients with asthma due to the increased risk of worsening of the patient's condition. Close monitoring of such patients for any adverse effects is necessary during treatment with this medicine.
Alendronate oral solution is not recommended for use in patients with obstruction of the gastrointestinal tract due to the increased risk of aspiration.
The desired effects of Alendronate will not be achieved if it is taken along with food. It is advised to take this medicine first thing in the morning and at least 30 minutes before eating or drinking anything.
The combined use of Alendronate and products containing calcium, magnesium, aluminum, or iron may reduce the effectiveness of this medicine. It is recommended not to take such products for at least 30 minutes after taking Alendronate. It is advised that you inform the doctor about all your medicines including herbs and supplements before beginning treatment with Alendronate to avoid such interactions.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.