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Alcinac-MR Tablet
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Alcinac-MR Tablet

Manufactured byLEEFORD HEALTHCARE LTD
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Tizanidine (2 mg)
Description
Alcinac-MR Tablet is a combination medicine which may be used for the treatment of pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It may also be used to relieve mild to moderate pain associated with muscle spasm such as low back pain, neck pain, sprains/strains, etc.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Alcinac-MR Tablet

  • Bloody and cloudy urine
  • Constipation
  • Nausea and vomiting
  • Chest pain or discomfort
  • Nervousness
  • Painful or burning urination
  • Unusual tiredness
  • Blurred vision
  • Irregular heartbeat
  • Itching skin
  • Shortness of breath
  • Weight gain
  • Abdominal pain
  • Skin rash

Uses of Alcinac-MR Tablet

What is it prescribed for?

  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Mild to Moderate Pain associated with Muscle Spasm
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to paracetamol, aceclofenac, any other NSAIDs, tizanidine, or any other inactive ingredients present in the formulation.

Severe liver impairment

This medicine is not recommended for use in patients suffering from severe liver impairment due to the increased risk of worsening of the patient's condition.

Asthma

This medicine is not recommended for use in patients suffering from asthma due to the increased risk of worsening of the patient's condition.

Gastro-intestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

CYP1A2 inhibitors

This medicine is not recommended for use in patients receiving CYP1A2 inhibitors such as fluvoxamine due to the increased risk of severe adverse effects.

Severe renal impairment

This medicine is not recommended for use in patients with severe kidney impairment due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Hypotension

This medicine should be used with caution in patients with hypotension (low blood pressure) or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure may be required for such patients.

Liver impairment

This medicine should be used with caution in patients with liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended for such patients. Therapy may need to be discontinued based on the clinical condition. This medicine is not recommended for use in patients suffering from severe liver impairment.

Kidney impairment

This medicine should be used with caution in patients with kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function and appropriate dose adjustments may be necessary based on the clinical condition. This medicine is not recommended for use in patients suffering from severe kidney impairment.

Bleeding disorders

This medicine should be used with extreme caution in patients with any bleeding disorders due to the increased risk of excessive bleeding. Report any unusual bruising or bleeding to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Anemia

This medicine should be used with caution in patients with anemia due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Gastro-intestinal bleeding

This medicine should be used with extreme caution due to the increased risk of severe gastrointestinal bleeding, especially with prolonged use. This risk is significantly higher in the elderly population and in patients with a history of gastrointestinal diseases. Report any unusual symptoms such as blood in the stool or vomit to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Heart surgery

This medicine is not recommended for use in patients with a history of recent heart surgery due to the increased risk of worsening of the patient's condition.

Driving or operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Chronic malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Atenolol

Citalopram

Clozapine

Lithium

Phenytoin

Amiodarone

Sodium Nitrite

Leflunomide

Prilocaine

Digoxin

Corticosteroids

Anticoagulants

Benazepril

Carbamazepine

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Renal Dysfunction

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Hypotension

This medicine should be used with caution in patients with a known history of hypotension or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure are recommended for such patients.
Food interactions
Consumption of caffeine may increase the undesired effects of this medicine. This may cause side effects such as drowsiness, dizziness, lightheadedness, fainting, irregular heartbeat, etc. Hence, you are advised to avoid the consumption of caffeine during treatment with this medicine.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. This medicine should be taken with food or immediately after food. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Aceclofenac and Paracetamol inhibit the formation of certain natural substances which are responsible for causing pain and inflammation. Tizanidine acts on the nervous system and reduces muscle spasms, allowing the muscles to relax.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Skeletal muscle relaxants

Schedule

Schedule H

DailyMed - Tizanidine Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1fa26940-3778-4758-811e-3e1531d919df

Tizanidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601121.html

DailyMed - Clanza CR- aceclofenac tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 15 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html
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Information on this page was last updated on 11 Jun 2019

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