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Adcapone Tablet
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Adcapone Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsEntacapone
Description
Adcapone Tablet is used in a combination with carbidopa and levodopa for the treatment of wearing-off symptoms of Parkinson's disease. These symptoms may include stiffness, tremors, muscle spasms, poor muscle control, etc. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Adcapone Tablet

Entacom 200 mg Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Adcapone Tablet

  • Constipation
  • Cough or hoarseness
  • Fever or chills
  • Lower back or side pain
  • Difficult or painful urination
  • Confusion
  • Shortness of breath
  • Unusual tiredness or weakness
  • Dizziness
  • Nausea
  • Dry mouth

Uses of Adcapone Tablet

What is it prescribed for?

  • Parkinson's Disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to entacapone or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Driving or Operating Machinery

Patients with Parkinson's disease are usually advised not to drive or operate machinery. Also, use of this medicine may cause symptoms such as dizziness, unusual tiredness or weakness, confusion, drowsiness, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during treatment with this medicine.

CNS disorders

This medicine should be used with caution in patients suffering from CNS (central nervous system) disorders due to an increased risk of severe side effects such as hallucinations, psychotic episodes, confusion, etc. The risk is especially higher in the elderly patients. Close monitoring of the patient for any changes in mood and behavior is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor on priority. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during treatment with this medicine. Appropriate patient/caregiver counseling, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Use in Pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Hepatic impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Low blood pressure

This medicine should be used with extreme caution in patients suffering from hypotension (low blood pressure) or patients receiving antihypertensive medications (high blood pressure medicines) due to the increased risk of a very low blood pressure. Regular monitoring of blood pressure levels is recommended for such patients. Report any symptoms such as lightheadedness, fainting, dizziness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Amitriptyline

Alprazolam

Amoxapine

Procarbazine

Linezolid

Disease interactions

Psychosis

This medicine should be used with extreme caution in patients suffering from psychosis due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine helps in increasing and maintaining the effects of levodopa, which is converted into dopamine and relieves the symptoms of Parkinson's disease.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Dopaminergic Antiparkinsonism agents

Schedule

Schedule H

Entacapone - DrugBank [Internet]. Drugbank.ca. 2018 [cited 25 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB00494

Entacapone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 25 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a601236.html

[Internet]. Mhra.gov.uk. 2018 [cited 25 July 2018]. Available from:

http://www.mhra.gov.uk/home/groups/par/documents/websiteresources/con224476.pdf

[Internet]. Pharma.us.novartis.com. 2018 [cited 25 July 2018]. Available from:

https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/comtan.pdf
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Information on this page was last updated on 7 Aug 2018

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