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Acetamide - 250 mg Tablet
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Acetamide - 250 mg Tablet

Manufactured byMICRO LABS LTD
ContainsAcetazolamide
Description
Acetamide - 250 mg Tablet is a medicine used to treat glaucoma (an eye condition with abnormally high pressure inside the eye that may eventually lead to blindness) and oedema (abnormal retention of fluids). It is used in the treatment of epilepsy (fits or convulsions) in combination with other medicines. Acetamide - 250 mg Tablet is also used to prevent or reduce the symptoms of mountain sickness. This medicine works by blocking the action of an enzyme in your body. It decreases the production of fluid within your eyes. Acetamide - 250 mg Tablet can cause side effects like nausea, diarrhoea, increased urge to urinate, decreased appetite, change of taste, numbness of fingers and toes, drowsiness, and flushing (redness of the skin, usually of the face). If you have blood in the urine or experience painful urination, seek medical help immediately. This medicine might cause drowsiness so avoid any activity which requires concentration like driving. Acetamide - 250 mg Tablet can be taken with or without food. Avoid the discontinuation of this medicine without consulting your doctor. For the ease of remembering, take the medicine at around the same time every day. Acetamide - 250 mg Tablet is not recommended if you are allergic to it. Inform your doctor if you are taking Acetamide - 250 mg Tablet before undergoing surgery. Inform your doctor if you have liver or kidney problems before taking Acetamide - 250 mg Tablet. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Acetamide - 250 mg Tablet

  • Diarrhoea
  • Vomiting
  • Loss of appetite
  • Numbness, tingling in arms or legs
  • Increased thirst
  • Increased urination frequency
  • Drowsiness
  • Headache
  • Confusion
  • Fever and cough
  • Blood in urine
  • Yellowing of skin and eyes
  • Sore throat
  • Unusual bleeding or bruising
  • Ringing or buzzing in the ears
  • Severe skin rash and hives
  • Change in taste
  • Decrease in sexual drive
  • Flushing

Uses of Acetamide - 250 mg Tablet

What is it prescribed for?

  • Glaucoma
  • Acute mountain sickness
  • Epilepsy
  • Oedema
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effects of Acetamide - 250 mg Tablet can be observed within 1 to 1.5 hours.
  • How long do the effects of this medicine last?
    The effect of Acetamide - 250 mg Tablet lasts for an average duration of 8 to 12 hours. This medicine may remain in your body for 18 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency was reported with Acetamide - 250 mg Tablet.
  • Can this medicine be taken during pregnancy?
    Acetamide - 250 mg Tablet is not recommended for use in pregnancy, unless absolutely necessary. All the benefits and risks should be discussed with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Acetamide - 250 mg Tablet may be taken with caution if you are breastfeeding. Consult your doctor to discuss the benefits and risks before taking this medicine.

Allergy

Acetamide - 250 mg Tablet is not recommended if you have a known allergy to this medicine. If you notice any symptoms such as a skin rash, hives (itchy, painful eruptions that sting), itching/swelling (especially in the face/throat/lips/tongue), breathing difficulty, etc., inform your doctor and seek immediate medical attention.

Severe liver impairment

Acetamide - 250 mg Tablet is not recommended if you have severe liver problems as it increases the risk of hepatic encephalopathy (condition when the liver fails to work properly thus, toxins start to build up in the blood that travels to the brain and affect brain function). This medicine should be used with extreme caution in case of mild to moderate liver impairment.

Severe kidney impairment

Acetazolamide is removed from the body through the kidneys. Hence, Acetamide - 250 mg Tablet is not recommended for use if you have severe impairment of kidney function as it increases the risk of serious side effects and other complications.

Chronic non-congestive angle-closure glaucoma

Angle-closure glaucoma is a condition that occurs when the iris (coloured tissue at the front of your eye with pupil in the centre) narrows or blocks the drainage angle (area of the eye which allows the fluid to drain from the eye). Hence, fluid cannot circulate through the eyes and lead to an increase in pressure. Acetamide - 250 mg Tablet is not recommended for use if you have chronic non-congestive angle-closure glaucoma as it may worsen your condition.

Altered levels of sodium/potassium

Acetamide - 250 mg Tablet may increase the excretion of potassium and sodium from your body. Therefore, this medicine is not recommended if you have low blood levels of sodium and/or potassium as it may worsen your condition.

Adrenal insufficiency

Adrenal insufficiency is a disorder that occurs when the adrenal glands fail to produce a sufficient amount of certain hormones. Acetamide - 250 mg Tablet is not recommended in such conditions as it increases the risk of severe side effects.
Warnings for special population

Pregnancy

Acetamide - 250 mg Tablet is not recommended for use in pregnancy, unless absolutely necessary. All the benefits and risks should be discussed with your doctor before taking this medicine.

Breast-feeding

Acetamide - 250 mg Tablet may be taken with caution if you are breastfeeding. Consult your doctor to discuss the benefits and risks before taking this medicine.
General warnings

Other medicines

Acetamide - 250 mg Tablet may interact with many other medicines and this may cause serious side effects. Hence, you should inform your doctor if you are taking any medicines, herbs, and/or supplements.

Use in children

Acetamide - 250 mg Tablet is not recommended for use in children since the safety and efficacy are not clinically established.

Use in elderly

Acetamide - 250 mg Tablet should be used with extreme caution in elderly people since the risk of side effects is significantly high. Close monitoring, appropriate dose adjustments or replacement may be necessary based on the condition.

Liver diseases

Acetamide - 250 mg Tablet should be used with caution if you have mild to moderate liver problems due to the increased risk of severe side effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary.

Kidney diseases

Acetamide - 250 mg Tablet should be used with caution in patients with mild to moderate kidney problems due to the increased risk of si effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary.

Respiratory diseases

Acetamide - 250 mg Tablet should be used with caution if you have a history of respiratory diseases such as COPD, respiratory acidosis, etc., since it may worsen your condition. Close monitoring of lung function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the patient's condition.

Driving or operating machines

Use of Acetamide - 250 mg Tablet may cause side effects such as muscle weakness, drowsiness, dizziness, and visual disturbances. If you experience any of these symptoms, avoid activities such as driving or operating a machine.

Missed Dose

If you forget to take a dose of Acetamide - 250 mg Tablet, take it as soon as you remember. If it is time for the next scheduled dose, then skip the missed dose. Do not take an extra amount of Acetamide - 250 mg Tablet to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Contact your doctor or seek emergency medical intervention if you suspect an overdose of Acetamide - 250 mg Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Dexamethasone

Pimozide

Insulin

Formoterol

Alprazolam

Choline salicylate

Digoxin

Carbamazepine

Amiodarone

Cisapride

Hydrocortisone

Zonisamide

Metformin

Aspirin

Sodium biphosphate

Magnesium salicylate

Disease interactions

Bone Marrow Depression/Blood Dyscrasias

Bone marrow depression is the decrease in bone marrow activity that results in reduced production of blood cells and anaemia. Acetamide - 250 mg Tablet should be used with caution if you have bone marrow depression or blood dyscrasias (disease or disorder of the blood) as it may worsen your condition. Your doctor may regularly monitor your complete blood counts and platelet count. Appropriate dose adjustment or replacement with a suitable alternative may be necessary based on your clinical condition.

Respiratory acidosis

Respiratory acidosis is a condition that occurs when your lungs are not able to remove the carbon dioxide produced in the body. Acetamide - 250 mg Tablet should be used with caution if you have respiratory acidosis or a history of lung problems as it can worsen your condition. Regular monitoring of the functioning of your lungs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary.

Diabetes Mellitus

Acetamide - 250 mg Tablet should be used with caution if you have Diabetes mellitus. An increase in blood sugar levels and altered blood potassium levels has been reported in people with diabetes receiving Acetamide - 250 mg Tablet. It is recommended that you regularly monitor your blood sugar levels and electrolyte levels. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on your clinical condition.

Gout

Gout is a condition that may occur due to an increased level of uric acid in your body. Acetamide - 250 mg Tablet reduces the excretion of uric acid from your body. Hence, if you have gout or gouty arthritis, it may deteriorate your condition. Close monitoring of uric acid levels is indicated. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on your clinical condition.

Metabolic acidosis

Long-term treatment with Acetamide - 250 mg Tablet can lead to metabolic acidosis (a condition in which there is excessive acid in the body fluids).
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Acetamide - 250 mg Tablet with or without food. Take it exactly as prescribed by your doctor. Avoid taking a higher dose or for a longer period than that advised by your doctor. Ensure that the course of treatment is completed. Do not stop the use of Acetamide - 250 mg Tablet without consulting your doctor. This medicine may increase your frequency of urination. Hence, take the last dose for the day in the early evening to prevent frequent urination at night. This medicine may decrease the potassium level in your body. Take potassium-rich food such as bananas or orange juice while taking Acetamide - 250 mg Tablet.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Acetamide - 250 mg Tablet blocks the actions of a certain enzyme in your body. This helps to lower the pressure within your eyes. It also decreases the accumulation of fluid in your body. This mechanism also helps to control seizures. It also increases the excretion of sodium, potassium, bicarbonate, and water from the body and helps in relieving the symptoms of altitude/mountain sickness
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Carbonic anhydrase inhibitors

Schedule

Schedule H

Medicines.org.uk. 2021. Acetazolamide 250mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 August 2021].

https://www.medicines.org.uk/emc/product/2785/smpc>

Drugs, H., 2021. Acetazolamide: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 3 August 2021].

https://medlineplus.gov/druginfo/meds/a682756.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - ACETAZOLAMIDE tablet. [online] Available at: < [Accessed 3 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c1c76f21-e1fc-40ea-947a-bc9c752f80c8>
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Information on this page was last updated on 7 Oct 2021

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