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Acenaac-SP Tablet
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Acenaac-SP Tablet

Manufactured byAstra Labs
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Serratiopeptidase (10 mg)
Description
Acenaac-SP Tablet is a combination medicine that consists of Aceclofenac, Paracetamol and serratiopeptidase. Acenaac-SP Tablet is used to treat pain, stiffness, and swelling at joints due to ankylosing spondylitis (a type of arthritis that causes lower back pain affecting the spine and large joints), osteoarthritis (a type of arthritis that occurs when flexible tissue at the ends of your bones wears down) and rheumatoid arthritis (an autoimmune disorder affecting many joints, including those in the hands and feet). It is also used to get relief from headaches, toothaches, backaches, menstrual pain, sprains, and strains. This medicine blocks the release of a chemical that causes pain and swelling. Acenaac-SP Tablet shows side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Do not use this medicine if you are allergic to it. Acenaac-SP Tablet may also cause dizziness and drowsiness. Do not drive or operate machines if you feel drowsy or dizzy after taking this medicine. Acenaac-SP Tablet should be taken with food, milk, or an antacid to avoid stomach irritation. Acenaac-SP Tablet relieves pain and swelling due to arthritic conditions but does not cure it. Do not self-medicate or use it beyond the prescribed duration. Acenaac-SP Tablet should be used with caution if you have a history of stomach or intestinal bleeding, asthma, and severe heart, liver and kidney problems. Inform your doctor if you have a history of any medical condition and your current/previous medication. This medicine may affect the development of your foetus. If you are pregnant, planning a pregnancy or a breastfeeding mother, consult your doctor before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Acenaac-SP Tablet

  • Nausea or vomiting
  • Fever
  • Allergic skin reaction
  • Mouth sores
  • Bloody and cloudy urine
  • Stomach irritation
  • Fatigue
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Indigestion

Uses of Acenaac-SP Tablet

What is it prescribed for?

  • Swelling and pain
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The pain-relieving effect of Acenaac-SP Tablet can be observed within an hour of oral intake.
  • How long do the effects of this medicine last?
    The duration for which Acenaac-SP Tablet remains active in the body is generally 10-12 hours, however this might vary from person to person. Take the medicine as prescribed by your doctor.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Acenaac-SP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Acenaac-SP Tablet.
  • Can this medicine be taken during pregnancy?
    Acenaac-SP Tablet is not recommended for use during pregnancy it may harm your foetus. Hence avoid using it. Your physician may advise an alternative with the same therapeutic response.
  • Can this medicine be taken while breast-feeding?
    You should avoid taking Acenaac-SP Tablet in breastfeeding, since traces of the medicine pass into breast milk and can affect your infant. Discuss the benefits and risks with your doctor before taking this medicine.

Allergy

Avoid taking Acenaac-SP Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms like skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Kidney diseases

Acenaac-SP Tablet is not recommended for use if you have kidney problems. A long term use and higher doses of some painkillers may harm normal kidney function. Ask your doctor/pharmacist how this medicine affects your kidney function.

Severe liver disease

People with liver problems need special consideration while taking Acenaac-SP Tablet. The use of this medicine is generally not recommended in severe liver problems because it can increase the risk of liver damage. Hence, consult your doctor before taking this medicine.

Gastrointestinal bleeding

Acenaac-SP Tablet is not recommended for use if you have gastrointestinal bleeding or any perforation disorders as it may worsen your condition.

Peptic Ulcer

Avoid the use of Acenaac-SP Tablet if you have a peptic ulcer or experiencing any symptoms of peptic ulcer. It could cause swelling and bleed in the stomach, colon, and anus.
Warnings for special population

Pregnancy

Acenaac-SP Tablet is not recommended for use during pregnancy it may harm your foetus. Hence avoid using it. Your physician may advise an alternative with the same therapeutic response.

Breast-feeding

You should avoid taking Acenaac-SP Tablet in breastfeeding, since traces of the medicine pass into breast milk and can affect your infant. Discuss the benefits and risks with your doctor before taking this medicine.
General warnings

Chronic malnutrition

Malnutrition and fasting can increase the risk of Acenaac-SP Tablet toxicity. Your doctor will adjust the dose as per your weight.

Long term use

Use of Acenaac-SP Tablet for more than 4 weeks is not advised due to the lack of safety and efficacy data for long-term use.

Bleeding disorders

Acenaac-SP Tablet may interfere with blood clotting causing bleeding or bruising. Use it very cautiously if you have bleeding disorders.

Surgeries

Stop taking Acenaac-SP Tablet at least 10-14 days before a scheduled surgery as it may increase the risk of bleeding during and/or after the procedure.

Driving or operating machines

Acenaac-SP Tablet may cause sleepiness or dizziness. Avoid driving vehicles and operating heavy machines after taking this medicine.

Missed Dose

If you forget to take a dose of Acenaac-SP Tablet at a scheduled time, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Never take Acenaac-SP Tablet more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Acenaac-SP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Digoxin

Corticosteroids

Aspirin

Antihypertensives

Disease interactions

Liver disease

Avoid taking Acenaac-SP Tablet if you have liver problems. This medicine can accumulate in the diseased liver and lead to further liver damage. Your doctor will suggest tests to monitor your liver functions while you take this medication.

Asthma

You may experience exacerbation of asthmatic episodes while taking Acenaac-SP Tablet. Hence it is not recommended for use if you have asthma, especially when you had experienced allergic reactions by using non-steroidal anti-inflammatory medicines.

Gastro-Intestinal toxicity

Long term use of Acenaac-SP Tablet can damage your stomach and intestine. Any symptom indicating ulceration and bleeding like chronic indigestion, the appearance of coffee coloured dry blood in stools or blood vomiting should be reported immediately to your doctor.

Kidney diseases

Prolonged use of high doses of Acenaac-SP Tablet may cause kidney problems, such as painful urination and protein or blood in the urine. Hence, your kidney functions need to be closely monitored.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

5-HIAA urine test measures the amount of serotonin in your body. Acenaac-SP Tablet can interfere with urine test and may give a false-positive result. Inform your doctor and lab technician about all your current medicines before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Acenaac-SP Tablet with or after food to avoid stomach irritation. Drink adequate water for easy swallowing. Never take more than the prescribed dose. It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Acenaac-SP Tablet affects you. Avoid consuming alcohol when taking Acenaac-SP Tablet as it may cause excessive drowsiness and increase the risk of liver damage. Avoid taking Acenaac-SP Tablet with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. Take Acenaac-SP Tablet at around the same time daily. Do not stop the use of this medicine without consulting your doctor. Do not break, crush or chew the tablet in the mouth. take it immediately after peeling it from the strip.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Acenaac-SP Tablet contains paracetamol, aceclofenac and serratiopeptidase. Paracetamol and Aceclofenac work by blocking the formation of certain chemical messengers in your brain that causes fever, pain and swelling. Serratiopeptidase reduces swelling and redness by breaking down certain abnormal proteins present at the site of the swelling and promotes healing.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Miscellaneous analgesics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac>

Pubchem.ncbi.nlm.nih.gov. 2021. Serrapeptase. [online] Available at: < [Accessed 8 April 2021].

https://pubchem.ncbi.nlm.nih.gov/substance/347911427>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Drugs, H., 2021. Acetaminophen: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 July 2021].

https://medlineplus.gov/druginfo/meds/a681004.html>

Medicines.org.uk. 2021. Aceclofenac 100 mg film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 August 2021].

https://www.medicines.org.uk/emc/product/4240/smpc>
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Information on this page was last updated on 6 Oct 2021

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