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Ace-Proxyvon SP Tablet
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Ace-Proxyvon SP Tablet

Manufactured byWockhardt Ltd.
ContainsAceclofenac (100 mg) + Paracetamol (325 mg) + Serratiopeptidase (15 mg)
Description
Ace-Proxyvon SP Tablet is a combination of Aceclofenac, Paracetamol and Serratiopeptidase. It is used to relieve pain and swelling in conditions like muscle pain, joint pain, ankylosing spondylitis (a condition causing pain due to fusing of bones in the spine), osteoarthritis (a type of arthritis that causes pain on movement due to wearing of the protective covering at the ends of the bones) and rheumatoid arthritis (a condition where the body's immunity attacks the joints and damages it). Ace-Proxyvon SP Tablet shows common side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. If any of these side effects persist for a long time, consult your doctor. Do not take this medicine if you are allergic to any components present in this medicine. Ace-Proxyvon SP Tablet should be taken with food to avoid any stomach discomfort. The dose and duration will be determined by your doctor based on the condition and how well it relieves your symptoms. Ace-Proxyvon SP Tablet may affect or get impacted by other medications that you are taking. Inform your doctor if you have peptic ulcers or any medical conditions of the liver and kidneys before taking this medicine. Ace-Proxyvon SP Tablet may increase the side effects such as dizziness, drowsiness and stomach bleeding if taken with alcohol. Hence avoid taking alcohol while you are on this medication. You should consult your doctor before taking this medication if you are pregnant, planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Ace-Proxyvon SP Tablet

  • Nausea or Vomiting
  • Allergic skin reaction
  • Mouth sores
  • Bloody and cloudy urine
  • Stomach irritation
  • Fatigue
  • Diarrhoea
  • Abdominal pain
  • Constipation

Uses of Ace-Proxyvon SP Tablet

What is it prescribed for?

  • Swelling and pain
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The pain-relieving effect of Ace-Proxyvon SP Tablet can be observed within one hour of intake.
  • How long do the effects of this medicine last?
    The duration of Ace-Proxyvon SP Tablet being active in the body is generally 10-12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Ace-Proxyvon SP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
  • Is this a habit forming medicine?
    Ace-Proxyvon SP Tablet has no habit-forming tendencies.
  • Can this medicine be taken during pregnancy?
    Ace-Proxyvon SP Tablet is not recommended for use during pregnancy due to increased risk of harmful effects on your foetus. Your physician may prescribe an alternative with the same therapeutic response.
  • Can this medicine be taken while breast-feeding?
    If you are a breastfeeding woman, avoid taking Ace-Proxyvon SP Tablet since traces of the medicine passes into the breast milk and can affect your baby. Discuss the benefits and risks with your doctor before taking this medicine.

Allergy

Avoid taking Ace-Proxyvon SP Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness and breathing difficulty, etc.

Kidney Disease

Ace-Proxyvon SP Tablet is not recommended for use in people having kidney problems associated with the excessive use of painkillers.

Severe liver impairment

Individuals with liver problems need special consideration while taking Ace-Proxyvon SP Tablet. This medicine gets absorbed in the liver. Therefore, if you take large amounts of this medicine, it may accumulate in your liver and cause further damage.

Gastrointestinal bleeding

Ace-Proxyvon SP Tablet may cause stomach and intestinal bleeding and ulcers. Therefore, it is not recommended for use if you have gastrointestinal bleeding or perforation disorders since it may worsen your condition.

Peptic Ulcer

Avoid the use of Ace-Proxyvon SP Tablet if you have a peptic ulcer(s) or are suspected of having it. It could cause severe swelling and bleeding in the stomach, colon, and anus.

Cardiovascular Disease

People with heart conditions like congestive heart failure (a condition that occurs when your heart muscle cannot pump blood as well as it should) should avoid Ace-Proxyvon SP Tablet due to the worsening of the heart's condition.
Warnings for special population

Pregnancy

Ace-Proxyvon SP Tablet is not recommended for use during pregnancy due to increased risk of harmful effects on your foetus. Your physician may prescribe an alternative with the same therapeutic response.

Breast-feeding

If you are a breastfeeding woman, avoid taking Ace-Proxyvon SP Tablet since traces of the medicine passes into the breast milk and can affect your baby. Discuss the benefits and risks with your doctor before taking this medicine.
General warnings

Bleeding disorders

Ace-Proxyvon SP Tablet may interfere with blood clotting and results in bleeding or bruising. Use it cautiously if you have bleeding disorders.

Liver/kidney Disease

Ace-Proxyvon SP Tablet can worsen your condition if you take it while having pre-existing liver/kidney problems. Your liver/kidney functions need to be monitored regularly while you take this medicine.

Chronic Malnutrition

Malnutrition and fasting can increase the risk of Ace-Proxyvon SP Tablet overdose. Your doctor will adjust the dose based on your body weight.

Long term use

Use of Ace-Proxyvon SP Tablet for more than four weeks is not advised due to the lack of safety and efficacy data for long-term use.

Surgeries

Stop taking Ace-Proxyvon SP Tablet at least 10-14 days before a scheduled surgery as it may increase the risk of bleeding during and/or after the procedure.

Driving or Operating machinery

Ace-Proxyvon SP Tablet may cause sleepiness or dizziness in some individuals. Avoid driving vehicles and operating heavy machines after taking this medicine.

Missed Dose

If you forget to take a Ace-Proxyvon SP Tablet dose, make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take Ace-Proxyvon SP Tablet more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Ace-Proxyvon SP Tablet may lower your blood pressure and can cause dizziness, headache and changes in heart rate.
Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Digoxin

Corticosteroids

Aspirin

Antihypertensives

Disease interactions

Liver Disease

People with liver problems need special consideration while taking Ace-Proxyvon SP Tablet. Overdose of this medicine can lead to its accumulation in the liver and damage it further.

Asthma

Ace-Proxyvon SP Tablet must be used with caution if you have asthma and if you are sensitive to NSAIDs (pain killers) as this medicine can trigger an asthma attack or cause allergic reactions like skin rashes, itching/swelling on your body, etc.

Gastro-Intestinal toxicity

Long term use of Ace-Proxyvon SP Tablet can cause damage to your stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall may occur.

Impaired kidney function

Prolonged use of high doses of Ace-Proxyvon SP Tablet may cause kidney problems, such as painful urination and protein or blood in the urine. Hence, close monitoring of kidney function is necessary.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Ace-Proxyvon SP Tablet can interfere with a urine test and may give a false-positive result. Inform your doctor and lab technician about all your current medicines before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Ace-Proxyvon SP Tablet orally with or after food to avoid stomach irritation Never take more than the prescribed dose. As it causes dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how Ace-Proxyvon SP Tablet affects you. Avoid consuming alcohol when taking Ace-Proxyvon SP Tablet as it may cause excessive drowsiness and increase the risk of liver damage. Do not take it with any other medicine containing Paracetamol or any drugs for pain/fever or cough-and-cold, without asking your doctor first. Take this medicine at around the same time daily. Follow the prescription and do not stop the use of this medicine without consulting your doctor. Do not break, crush or chew the tablet in the mouth.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Ace-Proxyvon SP Tablet is a combination of Aceclofenac, Paracetamol and Serratiopeptidase. Paracetamol helps in reducing the signals responsible for fever and pain. Aceclofenac works by reducing the formation of certain substances in the body that causes pain and swelling. Serratiopeptidase reduces swelling and redness through the breakdown of proteins present at the site of the swelling.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Miscellaneous analgesics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac>

Pubchem.ncbi.nlm.nih.gov. 2021. Serrapeptase. [online] Available at: < [Accessed 8 April 2021].

https://pubchem.ncbi.nlm.nih.gov/substance/347911427>

Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Medicines.org.uk. 2021. Aceclofenac 100 mg film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 August 2021].

https://www.medicines.org.uk/emc/product/4240/smpc>

Drugs, H., 2021. Acetaminophen: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 July 2021].

https://medlineplus.gov/druginfo/meds/a681004.html>
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Information on this page was last updated on 24 Nov 2021

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