Abciximab

Description

Abciximab is used to prevent the formation of blood clots during surgical procedures performed to treat blocked blood vessels. It may be used as an adjunct in procedures including balloon angioplasty, coronary stent placement, percutaneous coronary intervention (PCI), etc. This medicine is generally used with aspirin or heparin.

Side effects

Major & minor side effects for Abciximab

  • Bleeding
  • Blurred vision
  • Dizziness when getting up suddenly from a sitting position
  • Excessive sweating
  • Unusual tiredness or weakness
  • Black or tarry stools
  • Bleeding gums
  • Pinpoint red spots on skin
  • Chest pain or discomfort
  • Fever and chills
  • Eye pain and discomfort
  • Headache
  • Pale skin
  • Rapid weight gain
  • Swelling of hands and feet

Uses of Abciximab

What is it prescribed for?

  • Percutaneous Coronary Intervention
  • Unstable angina
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 72 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to abciximab or any other inactive ingredients present along with it.

Cerebrovascular accident

This medicine is not recommended for use in patients with a history of cerebrovascular accidents within the past 2 years due to the increased risk of worsening of the patient’s condition.

Active bleeding

This medicine is not recommended for use in patients with active internal bleeding due to the increased risk of worsening of the patient’s condition.

Thrombocytopenia

This medicine is not recommended for use in patients with thrombocytopenia (abnormally low number of platelets) due to the increased risk of worsening of the patient’s condition.

Uncontrolled hypertension

This medicine is not recommended for use in patients with severe uncontrolled hypertension due to the increased risk of worsening of the patient’s condition.

Oral anticoagulants

This medicine is not recommended for use in patients who have recently received any oral anticoagulants (within the past 7 days), unless the prothrombin time is lesser than or equal to 1.2, due to the increased risk of excessive bleeding.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient’s condition.

Intracranial neoplasm

This medicine is not recommended for use in patients suffering from an intracranial neoplasm due to the increased risk of worsening of the patient’s condition.

Major surgery

This medicine is not recommended for use in patients who have undergone major surgery or trauma within the past 6 weeks due to the increased risk of worsening of the patient’s condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
General warnings

Bleeding

This medicine should be used with extreme caution in patients with increased risk of bleeding events. The risk of bleeding is higher if the patient is taking any anticoagulant medicines. An alternative treatment option may be necessary in some cases based on the clinical condition.

Other medicines

Abciximab may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before receiving this medicine.

Allergic reactions

Use of this medicine may sometimes cause a potentially fatal allergic reaction. Therapy should be discontinued immediately if the patient suffers from severe allergic reactions.

Thrombocytopenia

Use of this medicine may cause a decrease in blood platelet levels. It is advised to monitor the blood platelet count prior to and during treatment with this medicine. An alternative treatment option may be necessary in some cases based on the clinical condition.

Laboratory tests

It is advised to identify pre-existing hemostatic abnormalities using appropriate laboratory tests before initiating the treatment course with this medicine.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Vitamin E

Heparin

Alteplase

Bivalirudin

Dabigatran

Streptokinase

Anisindione

Dipyridamole

Celecoxib

Citalopram

Clopidogrel

Desvenlafaxine

Apixaban

Ibuprofen

Fondaparinux

Diclofenac

Aspirin

Acalabrutinib

Ardeparin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by preventing the formation of blood clots during certain specific surgical procedures.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Glycoprotein platelet inhibitors

Schedule

Schedule H

Abciximab - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00054

[Internet]. Accessdata.fda.gov. 2018 [cited 10 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/1997/abcicen110597-lab.pdf

DailyMed - Abciximab injection, solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 10 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=033d4c3b-4630-4256-b8f7-9ed5f15de9a3

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 17 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.