Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
General warnings
Other medicines
5 Flucel 250 Injection may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.
Vaccinations or immunization
Vaccinations with live or attenuated strains of micro-organisms should be avoided while receiving this medicine due to the increased risk of worsening of the patient’s condition. Similarly, treatment with this medicine should not be initiated if the patient has been vaccinated recently.
Liver impairment
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Kidney impairment
This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Infections
Use of this medicine may weaken the immune system and make you more susceptible to opportunistic infections. Hence, it is recommended to take suitable precautionary measures to avoid infections during treatment with this medicine. Report any unusual symptoms to the doctor. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Diarrhea
Use of this medicine may cause moderate to severe diarrhea in some patients. Contact your doctor immediately if you have more than 5 episodes of loose stools within a 24-hour period in spite of dietary alterations and uptake of anti-diarrheal medications. Therapy may need to be discontinued in such cases based on the clinical condition of the patient.
Photosensitivity
This medicine may make you more sensitive to sunlight or tanning lights. You are advised to use sunscreen and wear protective clothing to avoid adverse reactions to sunlight during treatment with this medicine.
Driving or Operating machinery
Use of this medicine may cause symptoms such as blurred vision, dizziness, or drowsiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Laboratory tests
Certain laboratory tests may need to be performed before, during, after treatment with this medicine. Your doctor may advise periodic blood tests as well as tests to monitor the function of other organs like liver and kidney.
Hand-foot syndrome
Use of this medicine may cause redness, swelling, peeling of the skin in the palm of hands and feet. It is advised to modify normal activities of daily life to reduce friction and heat exposure of hands and feet for the entire treatment duration and beyond. If the symptoms are severe, therapy may need to be discontinued.
Nutrition
It is advised to maintain good nutrition during and after the therapy with this medicine. It is recommended to consult your doctor or a dietician with regards to appropriate diet changes during this period.
Delayed wound healing
Use of this medicine may delay the wound healing process. Contact your doctor and seek appropriate advice if a surgery is planned while receiving this medicine.
Contraception
It is advised to use suitable methods of contraception during and after therapy with this medicine. Pregnancy should be avoided while receiving this medicine. Contact your doctor immediately if pregnancy is suspected.
Blood cell counts
Usage of this medicine may alter the levels of blood cell components. Hence, caution is advised while initiating the therapy with this medicine in patients with a pre-existing blood cell disorder. Regular monitoring of white blood cells and platelet counts is advised while this medicine is being administered. An alternative treatment option may be necessary in some cases based on the clinical condition.
Cardiotoxicity
Usage of this medicine may increase the risk of heart-related complications. Hence, caution is advised while initiating the therapy in patients with any active heart condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.