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1-AL Total Syrup

Manufactured byFDC PVT LTD
ContainsParacetamol (125 mg/5 ml) + Phenylephrine (5 mg/5 ml) + Chlorpheniramine (0.5 mg/5 ml) + Sodium Citrate (60 mg/5 ml)
Description

1-AL Total Syrup is a combination medicine used for the treatment of flu-like symptoms such as fever, nasal congestion, body ache, headache, etc. This medicine is not recommended for use in patients below 2 years of age.

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Side effects

Major & minor side effects for 1-AL Total Syrup

  • Nausea or Vomiting
  • Bloody and cloudy urine
  • Sleepiness or unusual drowsiness
  • Dry mouth
  • Increase in the blood pressure
  • Nasal irritation
  • Difficult or painful urination
  • Visual disturbances

Uses of 1-AL Total Syrup

What is it prescribed for?

  • Flu-like Symptoms
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use by patients with a known history of allergy to Paracetamol, Phenylephrine, Chlorpheniramine, Sodium Citrate, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Benign prostatic hyperplasia

This medicine is not recommended for use in patients with benign prostatic hyperplasia (enlarged prostate) since it may cause increased difficulty in passing urine.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Hypertension

This medicine is not recommended for use in patients with severe hypertension due to the increased risk of worsening the patient's condition.

Ventricular tachycardia

This medicine is not recommended for use in patients with ventricular tachycardia due to the increased risk of worsening the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Epilepsy

This medicine should be used with caution in patients with epilepsy since it increases the risk of seizures. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with extreme caution in patients suffering from kidney function impairment or active kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating heavy machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Children

This medicine is not recommended for use in patients below 2 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Missed Dose

Take/Administer the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Antidiabetic drugs

Antidepressants

Beta blockers

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Glaucoma

This medicine should be used with extreme caution in patients with a history of glaucoma, or increased intraocular pressure due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Asthma

This medicine should be used with extreme caution in patients with asthma/COPD due to the increased risk of further lung problems like respiratory tract blockage. This risk is especially higher in elderly patients. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cardiovascular disease

This medicine should be used with extreme caution in patients with cardiovascular diseases due to the increased risk of side effects. Report any incidence of irregular heart rate and very high blood pressure to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Gastrointestinal blockage

This medicine should be used with extreme caution in patients with a gastrointestinal obstruction due to the increased risk of worsening the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of high blood sugars. Close monitoring of blood glucose levels is recommended while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take/Administer this medicine exactly as advised by your doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. It is advised that you should inform the doctor about all the medicines or herbal products that you are using and about all your medical conditions before taking this medicine. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Paracetamol works by increasing the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain. Phenylephrine acts by reducing the swelling of the blood vessels in the nasal passages, making it easier to breathe. Chlorpheniramine blocks the action of certain substances produced by the body which induces allergic reactions. Sodium citrate works by neutralizing the acid in stomach and urine. Their combination is thus effective for treating flu-like symptoms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous analgesics, Decongestants, Antihistamines

Schedule

Schedule H

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Phenylephrine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a606008.html

[Internet]. 2017 [cited 11 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/13691

Chlorphenamine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01114

Sodium Citrate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 4 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB09154
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Information on this page was last updated on 29 Mar 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.