My mother has been diagnosed with tb last month she started akt 4 treatment within 3-4 days her fever subsidised but after one week of taking att there was drug induced hepatitis due to which alternative regimen was started streptomycin levo etham for 11 days when her liver enzymes settled down isoniazid rifampicin pyrazinamide were introduced one by one but when all 4 medicine were introduced on 2nd day she was nauseous lft report of 4 th day show marked increase in alt so again s/l/e regimen was started after starting s/l/e regimen second time her fever and cough start again she also has pain in left shoulder is this normal in tb her tb treatment started 40 days back