This is a very reasonable question. If your
TSH, T3 and T4 are normal three months after stopping the tablet, then you do not need to restart Thyroxine 25 mcg right now. A small dose like 25 mcg is often started for mild subclinical hypothyroidism, and in many people, especially after weight change or a temporary thyroiditis, the gland recovers and the levels stay normal without medicine. What is important is follow up rather than restarting blindly. Please get TSH with free T4 repeated after 3 months and then every 6 months, and also get anti TPO antibody done once, because if it is positive there is a higher chance of hypothyroidism returning later and you will need closer monitoring. Do get tested earlier if you develop tiredness, weight gain, cold intolerance, constipation, dry skin, hair fall, irregular or heavy periods, or swelling of the face and feet. Also, please plan a TSH test before conception or as soon as you plan pregnancy, since the requirement changes then and untreated hypothyroidism in pregnancy is important to avoid. Kindly do not restart or stop
thyroid medicine on your own in future. You may consult me here (fee Rs 500) with your reports if you want a detailed review.