I need more details about your tumor size, margin status, and structures involved. The pathology wording ‘low-grade dedifferentiated liposarcoma’ is unusual—dedifferentiated type is usually high grade—so a second review of your slides/blocks at a sarcoma reference center (with MDM2 testing if not done) is strongly advised.
Next steps include a CT scan of the chest and imaging of the operated area to check for spread or residual disease. If margins are positive, bulky (>5 cm), or deep, radiotherapy may be considered. Chemotherapy is not routine after surgery for liposarcoma but may be discussed in high-risk cases. Final decisions should be made after review in a multidisciplinary sarcoma team
Answered2025-08-31 14:13:06
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