Hello, Sameral (S-Adenosyl Methionine) 400 mg is a supplement often used for liver health and sometimes in psychiatric conditions. Breaking the tablet into halves and swallowing is generally safe and will not reduce its effectiveness, provided it is not an enteric-coated or sustained-release formulation. Most commonly available SAMe tablets are film-coated but not sustained-release, so splitting is acceptable if it helps you swallow more easily.

You are taking full dose after dividing it in half You can take this medication in this form most important is to continue your all other medications and maintain follow up visits with your doctor You can discuss your queries too in follow up visits Opt healthy life style as avoid caffeine rich diet, oily fatty diet Include more fibre and fruit in your diet Smoke and alcohol should be avoided

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If it is not controlled release or extended release , you can have it like you are taking.