Hi, the bike-seat pressure on the perineum is not directly linked to the prostate problems, to my best knowledge. The bike seats, depending on their design, are known to press against the perineum (the area between the anus and the scrotum) and the blood vessels and nerves in that area, in those who spend long hours biking. Since you are experiencing distress, plesae try driving different vehicles, each for a day or two and check the seat shape and height that best suits you. Based on that, you may try reshaping your bike seat with the help of seat makers in your city. The seat should have a wider base to rest your pelvic bones, and in such an slant that makes you sit upright.