Hi there,
There is always a need for detailed medical and psychiatric history for every patient. In addition to that , a detailed mental status examination is also recommended for every patient.
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As per your query, Etizolam is primarily an anti anxiety drug.I relieves anxiety but can cause sedation and sleepiness also.
While Mirtazepine is primarily an antidepressant but can also cause sleepiness.
Such drugs are to be taken under the care of a mental health professional medical expert.
As such such drug combinations are prescribed and the advice about such is also given for specific periods and Etizolam drugs are also given on SOS basis.
Patients are advised not to drink or drive after consuming such drugs.
What other kind of contraindications you want to know, you have specify.