Methmild is not the drug of choice for treating depression, it's just an adjuvant drug added to anti depressants in order to keep you active. Fludac is the anti depressant drug that helps to treat depression. Even after using Fludac for two years still you are not better means you need to think of other alternatives. There are many reasons for non response or lack of desired response. It might be the dose, or the duration, or drug, poor compliance.