Hi, I wanted to ask for my mother , her MRI showed - 1) Chronic lacunar infarct in both gangliocapsular region 2) age related cerebral atrophy 3) T2/Flair subcortical hyper intensity in periventricular frontoparietal white matter  and bilateral subcortical white matter in centrum semiovale , is it serious , or life threatening , she was initially taking the medicines : Telmisartan with metraprolol succinate -50 mg Telmisartan with amlodipine - 50 mg night                  But BP was not controlled , so we changed medicines to cilnidipine-10 morning and metrosartan 50 mg night .                                                                                         She also had swelling in leg ,Is lacunar infarct in report, life threatening or not ?because our neurologist said it's nothing to worry about it's common in 62 year old , it's normal . She was taking rousovostatin for some days but stopped as she had swelling in leg but after changing medicine to metrosartan she is fine .