I have had a burning sensation during urination for 4 years. I’ve seen 7–8 doctors, done several urine tests, and taken antibiotics for a month many times, but nothing has helped. Ultrasounds of my kidneys, ovaries, and bladder have all been normal. Two years ago one scan showed slightly thick bladder walls, but treatment did not cure the issue. Recent ultrasounds again show everything normal. For the last 6 months, I also have dry piles and strong burning in my anus along with urinary burning. My creatinine and serum levels are normal. I had ASD open-heart surgery in 2022. I am 36 and married. Doctors say my urine and stool tests are normal, yet the burning continues. I drink plenty of water and avoid spicy and junk food. Uroflowmetry, urine trace, urine culture, semen culture, abdomen scan, GeneXpert test, and three mid-stream urine samples are all normal.