A new procedure REGENEXX by injecting the stemcells taken from own bone and injected into the joint. The link below may be useful.

By your description, patient is probably having osteoarthritis of knees. This is akin to wear and tear. Injections in the joint are of controversial value at best. That too only in early stages of disease. Injections usually have an effect which lasts only a few months. I will suggest not to get a feeling that injection will cure the disease. In advanced stages, replacement is a very good and effective treatment

Contrast Fomentation (Hot and Cold). Avoid Squatting- Avoid sitting Cross legged

Trust me, don't run from pillar to post searching wonder remedies. Only option is Knee replacement. Do it from a good surgeon and you will never repent.

Physiotherapy treatment best option then replacement. With treatment quadriceps exercises

Just go for best physiotherapy treatment. It will work much better than anything. I have treated the number of patients suffering from OA knee of more than 10 years. Believe or not they  can sit cross leg and have no pain.

Total Knee Replacement is the best solution provided their are no comorbid medical conditions

Early osteoarthritis knee ll respond to intra articular injections but there is always chances of infection but in case of severe arthritis injections won't help.

The efficacy of injection depends on the stage of osteoarthritis various variety of injections also available Can give a try of injections but it's only temporary in case it works if it's more than 8 years her present condition may respond with replacement better

Get physiotherapy sessions from a good experienced physio I don't see any reason why it can't be managed through strengthening and stretching sessions with adjunct therapeutic modalities.