This is a case of att induced hepatitis, it's usually caused by rifamipicin or pyrazinamide in the att regimens. There are two ways to deal with this, either stop all the att and start again one medicine at a time when
lft comes normal. Other way is to start levoflox or cipox along with ethambutol. Whatever the treatment you are saying is going on, it's seems not in tuning with the guidelines. Amikacin can also cause
kidney issues so better check kidney function tests regularly, if Amikacin is required for the patient, though it's not advised even after att induced hepatitis. And mdr tb doesn't develop like this so don't worry if att is to be stopped or restarted.
Next Steps
Take consultation for further advice on this matter