Tiotropium

Description

Tiotropium is a bronchodilator medicine that is used to control and prevent symptoms of respiratory diseases such as asthma and chronic obstructive pulmonary disease. This medicine is not recommended for use in patients below 12 years of age.

Side effects

Major & minor side effects for Tiotropium

  • Dry mouth
  • Constipation
  • Upper respiratory tract infection
  • Difficult or painful urination
  • Chest pain or discomfort
  • Nausea
  • Sweating
  • Dizziness
  • Difficulty with swallowing
  • Skin rash, hives, or itching
  • Fainting

Uses of Tiotropium

What is it prescribed for?

  • Chronic obstructive pulmonary disease
  • Asthma - Maintenance
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to tiotropium, ipratropium, atropine or its derivatives, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Driving vehicles and operating machinery

This medicine may cause symptoms such as dizziness or fainting in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Glaucoma

This medicine should be used with caution in patients suffering from pre-existing glaucoma due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Urinary retention

This medicine should be used with caution in patients suffering from benign prostatic hyperplasia due to the increased risk of urinary retention. Close monitoring of renal function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Use in children

For treatment of asthma, this medicine is not recommended for use in patients below 12 years of age. For treatment of chronic obstructive pulmonary disease, this medicine is not recommended for use in patients below 18 years of age.

Tachycardia

This medicine should be used with caution due to the increased risk of tachycardia (increased heart rate) and atrial fibrillation. Report any unusual symptoms such as changes in heart rate, palpitations, shortness of breath, dizziness, etc. to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Angioedema

This medicine should be used with caution due to the increased risk of angioedema. Report any symptoms such as swelling, rashes, hives, etc. immediately to the doctor. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atropine

Ipratropium

Doxepin

Chlorpheniramine

Doxylamine

Disease interactions

Renal Dysfunction

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients with a known history of liver diseases since the safety and efficacy of use are not clinically established for such patients. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Use this medicine exactly as prescribed. The prescribed dosage form, frequency, and duration of uptake are specific as per your needs. Do not use this medicine in larger or smaller quantities or for longer than recommended. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by relaxing and opening the blocked air passages leading to the lungs. It improves the airflow into the lungs and makes breathing easier.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anticholinergic bronchodilators

Schedule

Schedule H

Tiotropium - DrugBank [Internet]. Drugbank.ca. 2018 [cited 29 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB01409

[Internet]. Medicines.org.uk. 2018 [cited 29 March 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.1693.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 29 March 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021395s014lbl.pdf

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2018 [cited 29 March 2018]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 6 Apr 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.