Warnings for special population
Pregnancy
Praxet 12.5 MG Tablet CR is unsafe for use during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.
Breast-feeding
Praxet 12.5 MG Tablet CR is not recommended for use while breastfeeding unless necessary. Consult your doctor if you are breastfeeding.
General warnings
Suicidal thinking and behaviour
Praxet 12.5 MG Tablet CR may cause suicidal thoughts and behaviourial changes. Hence, if you experience any change in behaviour or develop suicidal thoughts, consult your doctor immediately.
Serotonin syndrome
Serotonin syndrome is a life-threatening condition that occurs when your body has too much of a chemical called serotonin. Praxet 12.5 MG Tablet CR should be used with caution as it may cause serotonin syndrome, especially if used along with other medicines to treat depression.
Neuroleptic malignant syndrome
Neuroleptic malignant syndrome is a life-threatening reaction to antipsychotic medicines characterised by fever, altered mental status, muscle rigidity, irregular pulse, increased rate of respiration, etc. Praxet 12.5 MG Tablet CR should be used with caution as it may cause neuroleptic malignant syndrome, especially if used along with other medicines to treat depression.
Bleeding disorders
Use of Praxet 12.5 MG Tablet CR may cause unusual bleeding and bruising. Hence this medicine should be used with caution if you have severe active bleeding or a hemorrhagic diathesis (tendency to bleed easily).
Seizure disorder
Seizure disorder is a neurological condition in which your brain activity becomes abnormal causing uncontrolled jerking of the body. Praxet 12.5 MG Tablet CR should be used with caution if you have seizures as it may worsen your condition.
Manic episodes
Mania is a mental health condition that involves a state of high energy and elevated or irritated mood. Praxet 12.5 MG Tablet CR may occasionally cause or activate mania. Hence it should be used with caution if you have a history of mania.
Hyponatremia
Hyponatraemia refers to low blood sodium levels. Praxet 12.5 MG Tablet CR may cause hyponatraemia in some cases. The risk is especially high in the elderly, or if you are volume-depleted (reduced fluid volume in the body) or are taking diuretics (medicines used to remove excess salt and water from the body). Your doctor may monitor your blood pressure and sodium levels regularly while you are taking this medicine.
Bone fractures
Praxet 12.5 MG Tablet CR should be used with caution as it may cause bone fracture if you have decreased bone mineral density. Hence, inform your doctor if you experience symptoms like unexplained bone pain, tenderness, swelling, or bruising.
Driving vehicles or operating machines
Praxet 12.5 MG Tablet CR may cause dizziness, confusion, or disorientation. Avoid performing activities that require high mental alertness like driving vehicles or operating machines if you experience any of these symptoms.
Sexual dysfunction
Use of Praxet 12.5 MG Tablet CR may cause sexual dysfunction such as decreased sexual desire, delayed ejaculation, erectile dysfunction (inability to get and maintain an erection firm enough for sexual intercourse), etc. Consult your doctor if you have any concerns.
Withdrawal symptoms
Praxet 12.5 MG Tablet CR may cause withdrawal symptoms if this medicine is discontinued abruptly. Hence, your doctor will gradually lower your dose over a period of several weeks or months. Do not stop taking the medicine without consulting your doctor.
Use in children
Praxet 12.5 MG Tablet CR is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.
Use in elderly
Praxet 12.5 MG Tablet CR should be used with caution in the elderly due to the increased risk of side effects.