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Norflox 400 MG Tablet
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Norflox 400 MG Tablet

Manufactured byCipla Ltd.
ContainsNorfloxacin (400 mg) + Lactic Acid Bacillus (120 Million Spores)
Description
Norflox 400 MG Tablet is used to treat bacterial infections in the urinary tract and gonococcal infections. Use this medicine with caution in the elderly population as it increases the risk of tendinitis and tendon rupture. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Norflox 400 MG Tablet

  • Nausea or vomiting
  • Dizziness
  • Headache
  • Abdominal pain
  • Weakness
  • Constipation
  • Back pain
  • Flatulence
  • Heartburn
  • Skin rash

Uses of Norflox 400 MG Tablet

What is it prescribed for?

  • Urinary tract infections
  • Gonorrhea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to norfloxacin, any other fluoroquinolones, lactic acid bacillus, or any other inactive ingredients present in the formulation.

Tendinitis or tendon rupture

This medicine is not recommended for use in patients with a known history of tendon rupture or tendinitis (a condition in which the tissue connecting muscles to the bones becomes inflamed) due to the increased risk of worsening of the patient's condition.

Myasthenia gravis

This medicine is not recommended for use in patients with a known history or family history of myasthenia gravis (weakness and rapid fatigue of muscles under voluntary control) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Tendinitis and tendon rupture

Use of this medicine may increase the risk of developing tendinitis or tendon rupture during the treatment or several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids such as dexamethasone, methylprednisolone, or prednisone. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

Use of this medicine may rarely cause symptoms such as blurred vision, drowsiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ethinyl Estradiol

Corticosteroids

Aspirin

Antidiabetic drugs

Disease interactions

Central nervous system disorders

This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities since it may worsen the patient's condition. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is advisable to avoid using caffeine-containing products while on therapy with this medicine.

QT Prolongation

This medicine should be used with extreme caution in patients with a history of QT prolongation due to the increased risk of worsening of the patient's condition. This risk is especially higher in patients with heart diseases or electrolyte disturbances and elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of altered blood glucose levels. Close monitoring of glucose levels is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
The desired effect of this medicine may not be obtained if it is consumed with any dairy products. You are advised to consume this medicine at least 1 hour before or 2 hours after consuming dairy products to avoid their interaction.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine with or without food, as directed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Norfloxacin works by inhibiting an enzyme required for the bacterial DNA to replicate. This blocks the multiplication and growth and results in the eventual death of the bacteria. Lactic acid bacillus helps in the restoration of body-friendly micro-organisms (intestinal flora) in the intestines.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Quinolones, Antidiarrheals/probiotics

Schedule

Schedule H

Norflox Tablets [Internet]. CiplaMed. 2019 [cited 6 November 2019]. Available from:

https://ciplamed.com/content/norflox-tablets

Norfloxacin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 6 November 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Norfloxacin

Probiotics Lactic Acid Bacillus [Internet]. Indogulfgroup.com. 2018 [cited 30 August 2018]. Available from:

http://indogulfgroup.com/AE%20-%20Probiotics-%20Lactic%20Acid%20Bacillus.asp
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Information on this page was last updated on 15 Nov 2019

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