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Losakind 25 MG Tablet

Manufactured byMankind Pharmaceuticals Ltd.
ContainsLosartan
Description
Losakind 25 MG Tablet is a blood pressure-lowering medicine. It is used alone or in combination with other medicines for the treatment of hypertension (high blood pressure) and to help protect the kidneys from damage due to diabetes. It is also used to reduce the risk of stroke (a condition that occurs due to reduced blood supply to the brain). Losakind 25 MG Tablet works by relaxing your blood vessels and lowering your blood pressure. Losakind 25 MG Tablet may cause common side effects such as fatigue, low blood pressure, cold hands and feet, headache, indigestion, diarrhoea, etc. Consult your doctor if these symptoms persist or worsen. This medicine may cause dizziness or drowsiness. Hence avoid driving vehicles or operating machines if you feel dizzy or drowsy. Losakind 25 MG Tablet may be taken with or without food. Take it at the same time every day to maintain a constant level of this medicine in your body. Appropriate lifestyle changes like a low salt and low-fat diet and regular exercise will help to get maximum benefits from the treatment. You may have to take this medicine for the long term. Hence, avoid discontinuing it without consulting your doctor, as it may worsen your condition. Losakind 25 MG Tablet should be avoided if you are allergic to it. Inform your doctor if you have lung, liver, kidney, or heart problems before beginning treatment with this medicine. Also, inform your doctor about all your current medicines to avoid any undesired effects. Losakind 25 MG Tablet is not recommended for use in children below six years of age. Consult your doctor if you are pregnant or are breastfeeding.

Side effects

Major & minor side effects for Losakind 25 MG Tablet

  • Stomach pain
  • Difficulty or painful urination
  • Back pain
  • Chest tightness
  • Dizziness
  • Weakness in arms, hands, legs or feet
  • Sore throat
  • Drowsiness
  • Headache
  • Cough
  • Edema
  • Constipation
  • Diarrhoea
  • Low blood pressure
  • Low blood sugar levels
  • High potassium levels in the blood

Uses of Losakind 25 MG Tablet

What is it prescribed for?

  • Hypertension
  • Diabetic Nephropathy
  • Hypertension with left ventricular hypertrophy
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Losakind 25 MG Tablet can be observed within 6 hours of intake.
  • How long do the effects of this medicine last?
    The effect of Losakind 25 MG Tablet lasts for an approximate duration of 24 hours after intake.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with Losakind 25 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Losakind 25 MG Tablet is unsafe for use during pregnancy as it can cause harm to your developing foetus.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of safety information, Losakind 25 MG Tablet is not recommended for use while breastfeeding.

Allergy

Avoid taking Losakind 25 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Aliskiren

Aliskiren is a medicine used to treat high blood pressure. Coadministration of Aliskiren and Losakind 25 MG Tablet may increase your risk of serious side effects such as kidney problems, hypotension (low blood pressure), and hyperkalaemia (high blood potassium levels). This risk is especially higher if you have diabetes (high blood sugar levels) or pre-existing kidney problems. Hence concurrent use is not recommended if you have diabetes and/or severe kidney problems.

Severe liver disease

Losakind 25 MG Tablet is not recommended for use if you have severe liver problems as it may further worsen your condition.
Warnings for special population

Pregnancy

Losakind 25 MG Tablet is unsafe for use during pregnancy as it can cause harm to your developing foetus.

Breast-feeding

Due to the lack of safety information, Losakind 25 MG Tablet is not recommended for use while breastfeeding.
General warnings

Hyperkalaemia

Losakind 25 MG Tablet may cause hyperkalaemia (high blood potassium levels). This may increase your risk of heart rhythm problems. Avoid potassium-rich foods (potatoes, bananas, etc) and potassium supplements during treatment with this medicine.

Impaired liver function

Losakind 25 MG Tablet is metabolized and broken down by the liver and should be used with caution if you have pre-existing liver problems, as it may increase the risk of undesired effects. Your doctor may closely monitor your liver function and recommend dose adjustments based on your clinical condition.

Use in children

Losakind 25 MG Tablet is not recommended for use in children below six years of age as the safety and efficacy data are not established.

Lifestyle modifications

While taking Losakind 25 MG Tablet, follow certain lifestyle modifications such as: -Taking a low salt diet -Maintaining an appropriate body weight by doing regular exercise -Quitting smoking and limiting alcohol intake This will help you to get maximum benefits from the treatment.

Driving or operating machines

Losakind 25 MG Tablet may cause dizziness or drowsiness in some cases. Hence, avoid driving vehicles or operating machines if you feel dizzy or drowsy during treatment with this medicine.

Missed Dose

Try not to skip a dose of Losakind 25 MG Tablet. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take more than the prescribed dose. Contact your doctor if you suspect an overdose with Losakind 25 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Dexamethasone

Aliskiren

Captopril

Insulin

Angiotensin converting enzyme inhibitors (ACEI's)

Nonsteroidal anti-inflammatory medicines

Sulfamethoxazole-trimethoprim

Benazepril

Disease interactions

Hypotension

Losakind 25 MG Tablet may increase your risk of hypotension (low blood pressure). This risk is especially higher if you have hyponatraemia (low blood sodium levels) or are volume-depleted (low fluid volume in the body). Monitor your blood pressure regularly while you are taking this medicine.

Congestive heart failure

Losakind 25 MG Tablet should be used with caution if you have severe congestive heart failure (heart is unable to pump blood efficiently) due to the increased risk of kidney damage and myocardial ischemia (a condition that occurs when blood flow to the heart muscle is obstructed). The risk is especially higher if you are sodium or volume-depleted (decreased sodium and fluid levels in the body).
Food interactions
Losakind 25 MG Tablet may increase the blood potassium levels in the body. Hence, avoid potassium-containing foods and supplements during treatment with Losakind 25 MG Tablet. Consult your doctor if you experience weakness, irregular heartbeat, confusion, or tingling of the hands and feet.
Lab interactions
Information not available.
Take Losakind 25 MG Tablet with or without food. Do not take more or less than the prescribed dose. Do not stop the use of this medicine without consulting your doctor, as it may worsen your condition. Losakind 25 MG Tablet may cause an increase in your blood potassium levels. Your doctor may suggest tests to periodically monitor your blood potassium levels while you are taking this medicine. Avoid driving vehicles or operating machines if you feel dizzy or drowsy after taking Losakind 25 MG Tablet.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Losakind 25 MG Tablet blocks the action of a chemical messenger that causes narrowing of the blood vessels. Hence, it relaxes the blood vessels and allows the blood to flow easily, thus lowering the blood pressure.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Angiotensin-II receptor blockers, Anti-hypertensive Agents

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use LOSARTAN POTASSIUM TABLETS safely and effectively. See full prescribing information for LOSARTAN POTASSIUM TABLETS. LOSARTAN POTASSIUM tablets, for oral use Initial U.S. Approval: 1995. [online] Available at: < [Accessed 24 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3cdcf8cc-4964-4c53-e054-00144ff88e88>

Drugs, H., 2021. Losartan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 24 May 2021].

https://medlineplus.gov/druginfo/meds/a695008.html>

Medicines.org.uk. 2021. COZAAR 12.5 mg, 25 mg, 50 mg and 100 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 24 May 2021].

https://www.medicines.org.uk/emc/medicine/8320>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 24 May 2021].

https://www.medicines.org.uk/emc/files/pil.5875.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Losartan. [online] Available at: < [Accessed 24 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Losartan>
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Information on this page was last updated on 4 Mar 2022

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