Celecoxib
Description
Celecoxib is used to relieve pain and inflammation in conditions like Arthritis, Dysmenorrhea. Drink adequate amount of water to minimize the stomach irritation. Close monitoring of liver function is necessary while receiving this medicine.
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Side effects
Major & minor side effects for Celecoxib
- Fever
- Swelling of feet or lower legs
- Increase in blood pressure
- Diarrhea
- Stomach pain
- Headache
- Heartburn
- Runny Nose
- Flatulence
- Decreased appetite
Uses of Celecoxib
What is it prescribed for?
- Rheumatoid Arthritis
- Osteoarthritis
- Ankylosing Spondylitis
- Dysmenorrhea
- Acute pain
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Concerns
Commonly asked questions
- Onset of actionThe peak effect of this medicine can be observed in 2 to 3 hours.
- Duration of effectThe effect of this medicine lasts for an average duration of 8 to 12 hours.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit forming tendency has been reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women.
- Usage while breast-feeding?This medicine is known to be excreted in breast milk. It is recommended in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
Not recommended in patients with known allergy to Celecoxib or other non-steroidal anti-inflammatory (NSAID) drugs.
Asthma
Not recommended in patients with a history of NSAID-induced asthma, rhinitis and urticaria.
Coronary Artery Bypass Surgery (CABG)
Not recommended in patients with recent heart surgery.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women.
Breast-feeding
This medicine is known to be excreted in breast milk. It is recommended in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Effect on heart
Celecoxib can have adverse effects on the heart, especially after a prolonged duration of use. It could increase the risk of diseases like stroke and heart attack which may be fatal.
Gastro-intestinal bleeding
This medicine may cause severe bleeding when taken for a long time. Elderly population with a history of gastrointestinal diseases are at a higher risk. Any symptoms of blood in stools and vomiting should be informed to the doctor.
Impaired kidney function
This medicine is known to cause kidney injury. Close monitoring of kidney function is necessary. The dose should be adjusted based on the CrCl (Creatinine Clearance). This medicine is not recommended in patients with severe kidney disease.
Impaired liver function
This medicine should be used with caution in patients with liver injury. In patients with moderate liver injury, the dose should be reduced by 50%. This medicine is not recommended in patients with severe liver disease.
Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for the next dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Corticosteroids
Adefovir
Antihypertensives
Disease interactions
Asthma
Celecoxib should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.
Fluid Retention and edema
Celecoxib should be taken only after consulting a doctor. Monitoring of blood pressure and heart conditions is necessary on a regular basisi during the course of therapy.
Food interactions
Information not available.
Lab interactions
Information not available.
Celecoxib should be taken following all labeled instructions. The duration and amount of medicine consumed should be as prescribed by the doctor. It can be taken with food or after food. Drink adequate amount of water to minimize the irritation caused in the stomach.
Miscelleneous
How it works
It works by inhibiting the formation of chemical substances in the body that cause pain and swelling.
Legal Status
Classification
Category
Nonsteroidal anti-inflammatory agents
Schedule
Schedule H
[Internet]. 2017 [cited 20 June 2017]. Available from:
Celecoxib: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 20 June 2017]. Available from:
DailyMed - CELECOXIB - celecoxib capsule [Internet]Dailymed.nlm.nih.gov. 2017 [cited 20 June 2017]. Available from:
TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 20 June 2017]. Available from:
Information on this page was last updated on 28 Sep 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.