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Zefu CV (250/62.5 mg) Tablet
Manufactured byFDC LTD
ContainsCefuroxime (250 mg) + Clavulanic Acid (62.5 mg)
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Description
Zefu CV (250/62.5 mg) Tablet is an antibiotic consisting of cefuroxime and clavulanic acid. It is used to treat bacterial infections affecting the lungs, nose, throat, ears, skin and urinary tract. It works by interfering with the formation of the bacterial cell wall. This weakens and eventually kills them. Zefu CV (250/62.5 mg) Tablet is not effective against infections caused by viruses.
Zefu CV (250/62.5 mg) Tablet has some common side effects such as diarrhoea, stomach pain, headache, weakness, nausea, and vomiting. As this medicine may cause dizziness or drowsiness, avoid driving vehicles or operating machines. Do not take this medicine if you are allergic to it. Contact your doctor if any side effects become severe or persist for a longer period. Zefu CV (250/62.5 mg) Tablet is not recommended for use in children below 12 years of age.
Zefu CV (250/62.5 mg) Tablet can be taken with or without food. For the ease of remembering, take this tablet around the same time every day. Once an antibiotic is started, it is always recommended that you finish the entire course of the treatment. Do not take antibiotics without consulting your doctor because unnecessary use of an antibiotic can reduce its effectiveness and also lead to antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics).
Zefu CV (250/62.5 mg) Tablet may interact with live vaccines. Hence, maintain a time gap of at least 2 hours between administration. Inform your doctor if you have any liver, kidney, seizure or gastrointestinal diseases before taking this medicine. If you are pregnant, planning pregnancy or are breastfeeding, it is recommended to take this medicine only after consulting your doctor. Do not consume alcohol while using this medicine as it can cause excessive drowsiness.
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Substitutes
List of substitutes for Zefu CV (250/62.5 mg) Tablet
Side effects
Major & minor side effects for Zefu CV (250/62.5 mg) Tablet
Diarrhoea
Chills
Headache
Chest pain
Difficult or painful urination
Shortness of breath
Change in taste
Abdominal pain
Acid or sour stomach
Uses of Zefu CV (250/62.5 mg) Tablet
What is it prescribed for?
Pharyngitis/Tonsilitis
Pharyngitis and tonsillitis are infections that cause swelling and soreness in the throat and tonsils. If the infection affects both the throat and the tonsils, it would be called pharyngotonsillitis. Zefu CV (250/62.5 mg) Tablet is used to treat pharyngitis, tonsillitis, and/or pharyngotonsillitis.
Acute maxillary Sinusitis
Sinusitis is the swelling of membranes that line your nose and surrounding sinuses. It is often caused by bacteria and sometimes, viruses and fungi. You may experience a stuffed nose and pain or pressure behind your eyes, nose, cheeks, or forehead. Zefu CV (250/62.5 mg) Tablet is used to treat bacterial sinusitis and provides relief in three to eight weeks.
Acute bronchitis
Bronchitis is the swelling and irritation of bronchial tubes that regulates air passage in the lungs. Zefu CV (250/62.5 mg) Tablet is used to treat bronchitis caused by bacteria. It is also used to treat a sudden worsening of chronic bronchitis (long-term inflammation of the bronchi) and subsequent bronchitis episodes.
Skin and soft tissue infections
Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Zefu CV (250/62.5 mg) Tablet is used to treat all skin infections including abscess caused by bacteria.
Uncomplicated urinary tract infections
An infection in any part of your urinary system (kidneys, bladder, ureters, or urethra) is called a urinary tract infection (UTI). UTIs are the most common infections in humans and women are at greater risk of getting this infection. UTIs are caused by bacteria and in some cases, viruses or fungi. Zefu CV (250/62.5 mg) Tablet is used to treat uncomplicated urinary tract infections caused by bacteria.
Lyme disease
Lyme disease is an infection caused by Borrelia burgdorferi. This infection is spread to humans through the bite of infected black-legged ticks that carries the bacteria. This condition can be treated in a few weeks by using antibiotics. Zefu CV (250/62.5 mg) Tablet is used in the treatment of Lyme disease.
Acute bacterial otitis media
Otitis media (AOM), is an infection of the middle ear (the area behind the eardrum), common in infants and young children. Zefu CV (250/62.5 mg) Tablet is used to treat acute otitis media caused by bacteria.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Zefu CV (250/62.5 mg) Tablet starts working within 2-3 hours after taking it.How long do the effects of this medicine last?
The effect of Zefu CV (250/62.5 mg) Tablet lasts for an average duration of 4-8 hours.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported for Zefu CV (250/62.5 mg) Tablet.Can this medicine be taken during pregnancy?
Zefu CV (250/62.5 mg) Tablet is safe to use in pregnancy to treat bacterial infections. However, it is recommended to use this medicine only after consulting your doctor.Can this medicine be taken while breast-feeding?
Zefu CV (250/62.5 mg) Tablet is safe to use during breastfeeding. It enters into breast milk at low levels. However, your doctor prescribes this medicine only if the benefits outweigh the risks. If it is used in your breastfeeding, the baby should be observed for symptoms such as diarrhoea and yeast infection.
Allergy
Avoid using Zefu CV (250/62.5 mg) Tablet if you are allergic to it. If you notice any symptoms such as a skin rash, itching/swelling (especially of the face/tongue/throat), dizziness, breathing difficulty, etc., inform your doctor and seek immediate medical attention.
Warnings for special population
Pregnancy
Zefu CV (250/62.5 mg) Tablet is safe to use in pregnancy to treat bacterial infections. However, it is recommended to use this medicine only after consulting your doctor.
Breast-feeding
Zefu CV (250/62.5 mg) Tablet is safe to use during breastfeeding. It enters into breast milk at low levels. However, your doctor prescribes this medicine only if the benefits outweigh the risks. If it is used in your breastfeeding, the baby should be observed for symptoms such as diarrhoea and yeast infection.
General warnings
Diarrhoea
Zefu CV (250/62.5 mg) Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while receiving this medicine.
Kidney diseases
Zefu CV (250/62.5 mg) Tablet should be used with caution if you have pre-existing kidney disease due to the increased risk of severe side effects. Your doctor may closely monitor your kidney functioning while on treatment with this medicine.
Antibiotic resistance
The entire course of treatment with Zefu CV (250/62.5 mg) Tablet should be completed, even if the condition gets better after receiving few doses, due to the chances of antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics).
Use in paediatrics
Zefu CV (250/62.5 mg) Tablet is not recommended for use in children below 12 years of age because the safety and efficacy data is not available.
Jarisch-Herxheimer reaction
Zefu CV (250/62.5 mg) Tablet may cause Jarisch-Herxheimer reaction in some patients when used for more than 7 days. The symptoms may include fever, chills, headache, low blood pressure, increased heart rate, etc.
Liver disease
Regular monitoring of the liver enzyme levels is recommended while taking Zefu CV (250/62.5 mg) Tablet and even after completion of the treatment with this medicine.
Missed Dose
Take the missed dose of Zefu CV (250/62.5 mg) Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Zefu CV (250/62.5 mg) Tablet, seek emergency medical treatment.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Amikacin
Chloramphenicol
Ethinyl Estradiol
Cholera Vaccine
Furosemide
Disease interactions
Colitis
Zefu CV (250/62.5 mg) Tablet can kill the helpful bacteria in your stomach or intestine and leads to diarrhoea. Therefore, use this tablet with extreme caution if you have any gastrointestinal diseases.
Liver disease
If you have liver problems, maintain caution while taking Zefu CV (250/62.5 mg) Tablet due to the risk of liver damage. Your doctor may adjust the dose of this medicine based on your clinical condition.
Seizure disorders
Use Zefu CV (250/62.5 mg) Tablet with caution if you have a seizure disorder or fits because it can trigger your condition. Seizure medicines can be continued by consulting your doctor. Your doctor may adjust the dose of Zefu CV (250/62.5 mg) Tablet based on your condition.
Kidney diseases
Zefu CV (250/62.5 mg) Tablet is filtered by the kidney and eliminated from your body through urine. If you have any kidney problem, caution should be maintained while takingZefu CV (250/62.5 mg) Tablet due to the risk of kidney damage.
Food interactions
Information not available.
Lab interactions
Ferricyanide test
Use of Zefu CV (250/62.5 mg) Tablet may give false-negative results of blood glucose with the ferricyanide test. It is recommended to undergo any alternative test after consulting your doctor while using this medicine.
Zefu CV (250/62.5 mg) Tablet is an antibiotic used to treat bacterial infections only. It is recommended to take this medicine with or without food. Never take more than the prescribed dose.
Complete the entire treatment course with Zefu CV (250/62.5 mg) Tablet to avoid antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). Consult your doctor if you experience any undesirable side effects.
Inform your doctor before taking Zefu CV (250/62.5 mg) Tablet if you are a pregnant or breastfeeding mother. Always maintain caution if you have any underlying conditions like liver, kidney and gastrointestinal problems.
Do not give your medicine to other people even if their condition appears to be the same as yours. Keep away from the reach of children and pets. Do not use it after the expiry date. Ensure that unused medicine is disposed of properly.
Miscelleneous
How it works
Zefu CV (250/62.5 mg) Tablet is a combination of cefuroxime and clavulanic acid.
Cefuroxime works by preventing the formation of bacterial cell walls, thereby stopping the infection to spread.
Clavulanic Acid reduces resistance and enhances the activity of Cefuroxime against bacteria. It is a beta-lactamase inhibitor that blocks the action of certain enzymes of bacteria.
Legal Status
Classification
Category
Second generation cephalosporins, Beta-lactamase inhibitors
Schedule
Schedule H
Medicines.org.uk. 2021. Cefuroxime 250mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 7 September 2021].
Drugs, H., 2021. Cefuroxime: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 September 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - CEFUROXIME AXETIL tablet. [online] Available at: < [Accessed 7 September 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 7 September 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Cefuroxime. [online] Available at: < [Accessed 7 September 2021].
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Information on this page was last updated on 21 Sep 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
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