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Xone 2000 MG Injection

Manufactured byAlkem Laboratories Ltd.
ContainsCeftriaxone
CURRENTLY UNAVAILABLE

Description

Xone 2000 MG Injection is an antibiotic used to treat bacterial infections affecting the lungs, throat, ears, heart, skin, urinary tract, etc. This medicine kills or stops the growth of bacteria causing the infection. Xone 2000 MG Injection is not effective against infections caused by viruses. Your doctor may advise Xone 2000 MG Injection alone or in combination with other medications to treat bacterial infections. Xone 2000 MG Injection shows side effects that include diarrhoea, pain at the injection site, rashes and alteration of the results of the liver function test. Do not use this medicine if you are previously allergic to it. Contact your doctor if any side effects are seen for a longer period of time. It is one of the effective antibiotics given to infants, children and adults. Xone 2000 MG Injection should not be taken on your own. It is injected into your vein or muscle by your doctor in a hospital or clinic. Your doctor will determine the dose you need each day and how often the injections should be given. Xone 2000 MG Injection may interact with calcium-containing products. Hence, consult your doctor about the use of Xone 2000 MG Injection if you are receiving calcium products. Complete the course of treatment with Xone 2000 MG Injection, as stopping it abruptly can lead to antibiotic resistance. This can cause your symptoms to return.
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Substitutes

List of substitutes for Xone 2000 MG Injection

Accuzon 2000 MG Injection
Macleods Pharmaceuticals Pvt. Ltd.
C Tri 2000 MG Injection
Zuventus Healthcare Ltd.
Gramocef 2000 MG Injection
Micro Labs Ltd.
Kefotax 2000 MG Injection
Strides Shasun Ltd.
Oframax 2000 MG Injection
Ranbaxy Laboratories Ltd.

Side effects

Major & minor side effects for Xone 2000 MG Injection

Black or tarry stools

Chills

Difficulty or painful urination

Headache

Diarrhoea

Stomach pain

Dizziness

Acid or sour stomach

Weakness

Excessive air or gas in stomach

Pain at the injection site

Rash

Abnormal liver function test

Uses of Xone 2000 MG Injection

What is it prescribed for?

Bacterial Meningitis

Bacterial meningitis is an infection of the meninges, the protective layer that surrounds the brain and spinal cord. This infection starts when bacteria get into your bloodstream and travel to your brain and spinal cord. Xone 2000 MG Injection is used to treat bacterial meningitis and prevents the further spread of infection.

Bacterial Septicemia

Bacterial septicemia is an infection that spreads when a large number of bacteria enters the blood. In this infection, the immune system that protects you from many conditions releases a lot of chemicals into your blood. These toxins are carried through the bloodstream to your entire body, leading to organ damage. Xone 2000 MG Injection is effective in Bacterial Septicemia as it prevents the further growth of bacteria.

Gonorrhoea

Gonorrhoea is a sexually transmitted infection (STI) caused by Neisseria gonorrhoea bacteria that infects both men and women. It spreads during vaginal, oral or anal sex without a condom or other barrier method. Xone 2000 MG Injection is a safe and effective medication used to treat gonorrhoea.

Urinary Tract Infection

An infection in any part of your urinary system- the kidneys, bladder, ureters, or urethra is called urinary tract infection(s) (UTIs). UTIs are one of the most common infections, and women are at greater risk of getting this infection. UTI's can occur as complicated or uncomplicated urinary tract infections. Xone 2000 MG Injection is used to treat both kinds of urinary tract infections caused by bacteria.

Community-Acquired Pneumonia

Community-acquired pneumonia (CAP) refers to pneumonia (a lung infection) that is acquired outside the hospital. CAP can be caused either due to bacteria or virus. Xone 2000 MG Injection is used to treat CAP caused by bacteria like Mycoplasma pneumonia, Streptococcus pneumonia, Haemophilus influenzae, etc.

Bone and joint infections

Osteomyelitis is an infection of the bone and septic arthritis is an infection in a joint. These infections can occur due to a bone/joint injury or through blood by which bacteria, virus, or fungi invade a bone/joint. Xone 2000 MG Injection is used for the treatment of osteomyelitis and septic arthritis caused by bacteria.

Skin and soft tissue infections

Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Xone 2000 MG Injection is used to treat all skin infections including abscess (painful collection of pus) caused by bacteria.

Acute bacterial otitis media

Otitis media (AOM), is an infection of the middle ear (the area behind the eardrum), common in infants and young children. Xone 2000 MG Injection is used to treat acute otitis media caused by bacteria.

Pelvic inflammatory disease

Pelvic inflammatory disease is an infection of the female reproductive organs caused by bacteria. In this infection, the bacteria first enter the vagina and move into the pelvic organs- fallopian tubes, ovaries, cervix, and the uterus, causing infection. Xone 2000 MG Injection is used to treat pelvic inflammatory disease.

Intra-abdominal Infections

Intra-abdominal infection (IAI) describes a number of infections. It includes peritonitis (swelling of the peritoneum-lining of the abdominal wall), pancreatitis (swelling of the pancreas- an organ located behind the lower part of the stomach), diverticulitis (swelling of diverticula- one or more small pouches in the intestine), cholecystitis (swelling of the gallbladder-a small digestive organ that sits just under the liver), and cholangitis (swelling of the bile duct). Xone 2000 MG Injection is used to treat infections occurring within the abdomen (belly) caused by bacteria.

Bacteremia

Bacteremia is the presence of bacteria in the blood. Bacteria can sometimes enter your bloodstream from dental or medical procedures or from infections. If this condition is left untreated, it can lead to septicemia. This is an infection of the blood caused by the bacteria and Xone 2000 MG Injection is used for the treatment of bacteremia.

Bronchitis

Bronchitis is the swelling and irritation of bronchial tubes that regulates air passage in the lungs. Xone 2000 MG Injection is used to treat bronchitis caused by bacteria.

Bacterial endocarditis

Bacterial endocarditis is an infection in the inner lining of the heart caused by bacteria. It occurs when bacteria from another part of your body travel through the blood and attach to damaged areas of your heart. Xone 2000 MG Injection is used to treat bacterial endocarditis.

Lyme disease

Lyme disease is an infection caused by Borrelia burgdorferi. This infection is spread to humans through the bite of infected black-legged ticks that carry the bacteria. The tick becomes infected after feeding on animals like birds, deer, or mice that carry bacteria. This condition can be treated in a few weeks by using antibiotics. Xone 2000 MG Injection is used for the treatment of Lyme disease.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Xone 2000 MG Injection starts immediately after taking the injection.

  • How long do the effects of this medicine last?

    Xone 2000 MG Injection may remain in the body for up to 48 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendency has been reported for Xone 2000 MG Injection.

  • Can this medicine be taken during pregnancy?

    Xone 2000 MG Injection may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Xone 2000 MG Injection only upon your doctor's recommendation.

  • Can this medicine be taken while breast-feeding?

    Xone 2000 MG Injection may be passed into human milk in a low amount. Hence, it should only be used only if your doctor prescribes it. If you are using this medicine while breastfeeding, then observe your baby for symptoms such as diarrhoea.

Allergy

Avoid using Xone 2000 MG Injection if you are allergic to it. Inform your doctor if there is any history of allergy to Xone 2000 MG Injection. If you notice any symptoms such as skin rashes, itching/swelling, dizziness, breathing difficulty, etc., inform your doctor and seek immediate medical attention.

Lidocaine

Xone 2000 MG Injection should not be used with lidocaine as a solvent for intravenous injection or infusion. However, lidocaine can be used as a solvent for the intramuscular route of injection for this medicine, despite contraindications.

Calcium-containing products

Xone 2000 MG Injection should not be used in neonates (babies ≤ 28 days) who are receiving calcium-containing intravenous solutions or infusions such as parenteral nutrition because of the risk of accumulation of this medicine with calcium in the lungs and kidneys.

Warnings for special population

Pregnancy

Xone 2000 MG Injection may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Xone 2000 MG Injection only upon your doctor's recommendation.

Breast-feeding

Xone 2000 MG Injection may be passed into human milk in a low amount. Hence, it should only be used only if your doctor prescribes it. If you are using this medicine while breastfeeding, then observe your baby for symptoms such as diarrhoea.

General warnings

Antibiotic resistance

Antibiotic resistance occurs when bacteria develop the ability to defeat the medicine that was intended to kill them. Hence, to avoid such resistance, you should always complete the entire course of treatment with Xone 2000 MG Injection even if you feel better after a few doses.

Diarrhoea

Xone 2000 MG Injection can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while receiving this medicine.

Haemolytic anaemia

Haemolytic anaemia is a condition in which red blood cells are destroyed faster than they can be made in the body. Haemolytic anaemia due to immune activity has been observed in people receiving Xone 2000 MG Injection. Your doctor will suggest tests to closely monitor your haemoglobin levels. Consult your doctor in case you experience symptoms of anaemia like breathlessness on exertion, fast heartbeat, fatigue and dizziness.

Driving or operating machines

Xone 2000 MG Injection may cause side effects such as dizziness. Thus, it may affect your ability to drive vehicles or operate machines.

Missed Dose

Since Xone 2000 MG Injection is given in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since Xone 2000 MG Injection is given in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Amikacin

Furosemide

Probenecid

Cholera Vaccine (live)

Disease interactions

Colitis

Colitis is the inflammation of the large intestine. Xone 2000 MG Injection can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Therefore, use Xone 2000 MG Injection with extreme caution if you have any stomach and intestinal problems, particularly colitis, as it may worsen your health condition.

Seizure disorders

Seizure disorder(fits) is a condition due to uncontrolled electrical activity between brain cells that causes temporary abnormalities in muscle tone and movements, behaviour, etc. Avoid using Xone 2000 MG Injection or maintain caution if you have any history of seizure episodes, as it can trigger the condition. Your doctor will adjust the doses or suggest a suitable replacement as required.

Impaired kidney function

Xone 2000 MG Injection is filtered by the kidney and moved out of the body through urine. If you have any medical conditions that affect the kidneys, Xone 2000 MG Injection has to be taken with caution due to the increased risk of kidney damage.

Impaired liver function

Xone 2000 MG Injection may increase liver enzyme levels and cause liver swelling. Hence, maintain caution during treatment with Xone 2000 MG Injection due to the risk of liver damage.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Xone 2000 MG Injection is for parenteral use. It should be given by a qualified healthcare professional in the clinical or hospital setting. Your doctor will determine an appropriate dosage based on your clinical condition. You should not take Xone 2000 MG Injection on your own. Report any undesirable side effects to your doctor promptly.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

Xone 2000 MG Injection works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of bacteria and eventually kills them.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Third generation cephalosporins, Antibiotics

Schedule

Schedule H1

Dailymed.nlm.nih.gov. 2021. Ceftriaxone for Injection, USP. [online] Available at: < [Accessed 11 February 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dd1be9e-74cc-48e8-bf02-f34a78d80fda>

Drugs, H., 2021. Ceftriaxone Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 11 February 2021].

https://medlineplus.gov/druginfo/meds/a685032.html>

Medicines.org.uk. 2021. Ceftriaxone 1 g powder for solution for injection or infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 11 February 2021].

https://www.medicines.org.uk/emc/product/10604/smpc>

Go.drugbank.com. 2021. Ceftriaxone | DrugBank Online. [online] Available at: < [Accessed 23 February 2021].

https://go.drugbank.com/drugs/DB01212>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 11 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/065169s022lbl.pdf>

Labeling.pfizer.com. 2021. [online] Available at: < [Accessed 11 February 2021].

http://labeling.pfizer.com/ShowLabeling.aspx?id=7378>

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Information on this page was last updated on 14 Sep 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.