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Valprol-CR-300 Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsSodium Valproate (200 mg) + Valproic Acid (87 mg)
CURRENTLY UNAVAILABLE

Description

Valprol-CR-300 Tablet is an anticonvulsant medication that consists of Sodium Valproate and Valproic Acid. It is used for the treatment of epilepsy, a neurological disorder in which the brain activity becomes abnormal, leading to uncontrolled jerking movements and loss of consciousness. This medicine works by decreasing the abnormal and excessive activity of the nerve cells in your brain. Valprol-CR-300 Tablet may cause side effects like nausea, vomiting, diarrhoea, headache, change in appetite, tremor, confusion, etc. Inform your doctor if these side effects bother you for a long time or become worse. Avoid driving vehicles or operating machines after taking this medicine, as it may cause drowsiness. Valprol-CR-300 Tablet is advised to be taken with food to avoid stomach discomfort. The dose and duration of treatment will be decided by your doctor based on your condition. Take this medicine for the recommended duration for better results. Do not stop taking Valprol-CR-300 Tablet suddenly, as it may cause increased seizure frequency. Your doctor may gradually taper the dose over a period. Valprol-CR-300 Tablet should be avoided if you are allergic to it. Inform your doctor about your complete medical history, including any heart, liver, or kidney problems. Also, inform your doctor about all your current medications to avoid undesired effects. If you are pregnant, planning a pregnancy, or are breastfeeding, consult your doctor before taking Valprol-CR-300 Tablet.
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Substitutes

List of substitutes for Valprol-CR-300 Tablet

Side effects

Major & minor side effects for Valprol-CR-300 Tablet

Nausea or Vomiting

Diarrhea

Blurred vision

Dizziness

Weight gain

Body pain

Skin rash

Sneezing

Dry skin

Urinary incontinence

Drowsiness

Change in appetite

Tremor

Hair loss

Confusion

Uses of Valprol-CR-300 Tablet

What is it prescribed for?

Epilepsy

Epilepsy is a neurological condition in which your brain activity becomes abnormal, causing uncontrolled jerking movements and loss of consciousness. Valprol-CR-300 Tablet is used in the treatment of all types of epilepsy.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for Valprol-CR-300 Tablet to show its action is not clinically established.

  • How long do the effects of this medicine last?

    The amount of time for which Valprol-CR-300 Tablet remains active in your body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended while taking Valprol-CR-300 Tablet as it may increase the risk of side effects such as dizziness, drowsiness, and difficulty in concentration.

  • Is this a habit forming medicine?

    No habit-forming tendency has been reported for Valprol-CR-300 Tablet.

  • Can this medicine be taken during pregnancy?

    Valprol-CR-300 Tablet is unsafe for use during pregnancy as it can harm your developing foetus. Therefore, consult your doctor if you are pregnant.

  • Can this medicine be taken while breast-feeding?

    Valprol-CR-300 Tablet is not safe for use while breastfeeding as it passes into the breastmilk and may harm your baby. Therefore, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Valprol-CR-300 Tablet if you are allergic to it. Seek medical attention if you notice any symptoms like skin rash, itching/swelling (especially in the face/throat/tongue), dizziness, breathing difficulty, etc.

Active liver disease

Valprol-CR-300 Tablet is not recommended for use if you have active liver problems due to the increased risk of liver toxicity.

Urea cycle disorders

Urea cycle disorders are a group of genetic disorders that affect how protein is broken down in your body. It may lead to the accumulation of toxic waste products in the blood. Valprol-CR-300 Tablet is not recommended for use if you have urea cycle disorders as it may increase the risk of other complications that may be life-threatening.

Mitochondrial disorders

Mitochondrial disorders are a group of genetic disorders that occur when mitochondria (a component of the cell that produces energy) fail to produce enough energy for your body to function properly. Valprol-CR-300 Tablet is not recommended for use if you have mitochondrial disorders (e.g., Alpers-Huttenlocher Syndrome) as it may further worsen your condition.

Porphyria

Porphyria is a condition that occurs due to the build-up of a chemical called porphyrin in your body. It affects the production of heme which transports oxygen in your blood. It can cause nerve or skin problems. Valprol-CR-300 Tablet is not recommended for use if you have porphyria as it may worsen your condition.

Warnings for special population

Pregnancy

Valprol-CR-300 Tablet is unsafe for use during pregnancy as it can harm your developing foetus. Therefore, consult your doctor if you are pregnant.

Breast-feeding

Valprol-CR-300 Tablet is not safe for use while breastfeeding as it passes into the breastmilk and may harm your baby. Therefore, consult your doctor if you are breastfeeding.

General warnings

Pancreatitis

Pancreatitis is a swelling of the pancreas (a gland that produces chemical substances which help in digestion and regulation of blood sugar). Valprol-CR-300 Tablet should be used with caution as it may cause severe pancreatitis in some cases. Inform your doctor if you experience any signs and symptoms such as nausea, vomiting, or acute abdominal pain that persist or worsen.

Impaired kidney function

Valprol-CR-300 Tablet should be used with caution if you have kidney problems, as it may lead to the accumulation of this medicine in the body and increase the risk of undesired effects. Your doctor may adjust the dose of this medicine based on your clinical condition.

Lupus erythematosus

Lupus erythematosus is an autoimmune disorder (a condition where the immune system attacks its own tissues) that causes swelling and tissue damage in the affected organs. Valprol-CR-300 Tablet should be used with caution if you have lupus erythematosus, as it may worsen your condition.

Driving and operating machines

Valprol-CR-300 Tablet may cause drowsiness or dizziness. Hence, avoid driving vehicles or operating machines if you feel drowsy or dizzy after taking this medicine.

Missed Dose

Take the missed dose of Valprol-CR-300 Tablet as soon as you remember. If it is time for the next scheduled dose, skip the missed dose. Do not use extra medicine to make up for the missed dose.

Overdose

Never take more than the recommended dose. Contact your doctor in case of an overdose of Valprol-CR-300 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Valprol-CR-300 Tablet as it may increase the risk of side effects such as dizziness, drowsiness, and difficulty in concentration.

Interaction with Medicine

Lamotrigine

Metoclopramide

Warfarin

Disease interactions

Depression

Valprol-CR-300 Tablet should be used with caution due to the increased risk of depression and suicidal thoughts. If you notice any behavioural changes or develop thoughts of self-harm, consult your doctor immediately.

Food interactions

Information not available.

Lab interactions

Thyroid function tests

Thyroid function tests are blood tests done to measure the thyroid hormones level in your blood. Valprol-CR-300 Tablet may alter the results of thyroid function tests. Hence, inform your doctor and laboratory technician about the use of this medicine before undergoing the test.

Urine ketone test

A urine ketone test is done to check the level of ketones (chemicals made in your liver) in your urine. Valprol-CR-300 Tablet may give a false-positive result for the urine ketone test. Hence, inform your doctor and laboratory technician about the use of this medicine before undergoing the test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Valprol-CR-300 Tablet preferably with food to avoid stomach discomfort. Do not take in larger or smaller amounts than advised. Take this medicine for the recommended duration. Consult your doctor if you experience any undesirable effects that persist or worsen. Avoid consumption of alcohol while taking this medicine as it may increase the risk of side effects. Valprol-CR-300 Tablet may cause weight gain. Hence, monitor your weight while you are taking this medicine and adopt appropriate measures to minimise it.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

Valprol-CR-300 Tablet contains Sodium Valproate and Valproic Acid. Both medicines work by increasing the amount of a certain nerve-calming substance in your brain and decreasing the abnormal and excessive activity of the nerve cells.

Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Anticonvulsants Agents

Schedule

Schedule H

Drugs, H., 2022. Valproic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 February 2022].

https://medlineplus.gov/druginfo/meds/a682412.html>

Dailymed.nlm.nih.gov. 2022. DailyMed - VALPROATE SODIUM- valproate sodium injection, solution. [online] Available at: < [Accessed 18 February 2022].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3dfb6da1-f66a-4618-9f74-d2d6c16c0b58#:~:text=Valproate%20sodium%20injection%20is%20intended%20for%20intravenous%20use%20only.&text=Complex%20Partial%20Seizures%20in%20Adults,kg%2Fday%20(2.1).>

Related Questions

Question:
I'm on a daily dosage of valprol CR300 twice a day. I'm 5'9" and weigh 70kgs  currently. In a recent...more
Answer from Dr. Rashmi T V
Hi Never stop medication unless advised by neurologist which is rare.... As att...more
Question:
Right Now i am Taking Valprol CR 500 from last one month.Earlier i have seizures disorder.for that t...more
Answer from Dr. Akhila Kumar Panda
Can u please mention your weight Sometimes when we start Valprol u may have diz...more
Question:
Dear Sir, We are taking valprol cr 500 long times now I got married and planning for baby. Is that o...more
Answer from Dr. Shanthi
no..consult ur doctor if planning for pregnancy..
Question:
I had migraine but now and a doctor prescribed me Valprol - CR-300 but now due to it's side effects ...more
Answer from Dr. Prof. C.R.V.Narasimhalu
Specific medicine available.... Do direct online consultation  by sending photos...more
Question:
I have ceaser (fit ) problem since 06/07/2014 , Since then I have got one fit and one mild unconscio...more
Answer from Dr. Swati Khullar
Since u have ur last seizure episode 2 yrs back and u started treatment at that ...more
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Information on this page was last updated on 28 Feb 2022

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