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Tinidazole
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Description
Tinidazole is an antiprotozoal which helps in treating infections in the stomach, genital areas. Take this medicine with food to minimize gastric irritation. Do not take this medicine with alcohol. Take this medicine only if it is necessary to reduce the development of resistance.
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Side effects
Major & minor side effects for Tinidazole
Difficulty in breathing
Cough
Change in taste/ Metallic taste
Acid or sour stomach
Dizziness
Headache
Loss of appetite
Nausea and Vomiting
Dry mouth
Mood swings
Body pain
Uses of Tinidazole
What is it prescribed for?
Amebiasis
Tinidazole is used in the amebiasis which is a parasitic infection that affects the intestine
and amebic liver abscess caused by Entamoeba histolytica.
Trichomoniasis
Tinidazole is used in the treatment of trichomoniasis which is a sexually transmitted disease caused by Trichomonas vaginalis.
Bacterial Vaginosis
Tinidazole is used in the treatment of overgrowth of bacteria in the vagina caused by Lactobacillus species.
Concerns
Commonly asked questions
Onset of action
The effect of this medicine can be observed in 1 to 2 hours.Duration of effect
The effect of this medicine lasts for an average duration of 24 hours.Safe with alcohol?
Consumption of alcohol is not recommended in patients with Tinidazole. Any symptoms of the fast heartbeat, warmth, headache, and breathing difficulty should be reported to the doctor.Is it habit forming?
No habit forming tendencies were reported.Usage in pregnancy?
This medicine is not recommended in the first trimester of pregnancy. It can be used in the second and third trimesters of pregnancy only if clearly needed.Usage while breast-feeding?
This medicine is known to excreted through the breastmilk. The child should not breastfeed while taking this medicine and for at least 3 days after the last dose.
Allergy
Not recommended in patients with known allergy to Tinidazole or other nitroimidazoles.
Warnings for special population
Pregnancy
This medicine is not recommended in the first trimester of pregnancy. It can be used in the second and third trimesters of pregnancy only if clearly needed.
Breast-feeding
This medicine is known to excreted through the breastmilk. The child should not breastfeed while taking this medicine and for at least 3 days after the last dose.
General warnings
Blood cell count
This medicine may lower the blood cell count and may lead to leukopenia, thrombocytopenia, and bone marrow aplasia. Close monitoring of WBC count, platelets is necessary. Discontinue the treatment if any signs of low blood cell count appear.
Neurologic Toxicity
This medicine may cause neurological effects like convulsions and peripheral neuropathy. Inform the doctor if you have any neurological problems. Any symptoms of convulsions, tingling or burning sensation of hands and feet should be reported to the doctor.
Impaired liver function
This medicine may cause liver injury. The baseline of liver enzymes should be obtained before initiating the therapy. Any signs of elevation in the liver enzymes should be informed to the doctor. Discontinue the treatment until the levels reach to normal.
Missed Dose
If you miss a dose of Tinidazole, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Use of alcohol or products containing alcohol during nitroimidazole therapy may result in a disulfiram-like reaction in some patients. The proposed mechanism is inhibition of aldehyde dehydrogenase (ALDH) similar to disulfiram.
Instructions
Consumption of alcohol is not recommended in patients with Tinidazole. Any symptoms of the fast heartbeat, warmth, headache, and breathing difficulty should be reported to the doctor.
Interaction with Medicine
Warfarin
Cholera Vaccine
Atorvastatin
Disulfiram
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Tinidazole as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Miscelleneous
How it works
It works by inhibiting the growth of bacteria and protozoa by interfering with its DNA synthesis.
Legal Status
Classification
Category
Anthelmintics
Schedule
Schedule H
[Internet]. 2017 [cited 27 April 2017]. Available from:
Tinidazole: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 April 2017]. Available from:
DailyMed - Tinidazole tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:
Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 27 April 2017]. Available from:
[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:
Information on this page was last updated on 16 Nov 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.