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Silodal-D 4 Combipack
Manufactured bySUN PHARMA LABORATORIES LTD
ContainsSilodosin (4 mg) + Dutasteride (0.5 mg)
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Description
Silodal-D 4 Combipack is a combination of Silodosin and Dutasteride. It is used to treat the symptoms of benign prostatic hyperplasia (BPH) in men. BPH is a condition that causes enlargement of your prostate gland leading to urinary problems like difficulty in urination, increased frequency, weak urine stream, etc. This medicine works by relaxing the muscles in your urinary bladder, urethra, and prostate. It also blocks the production of a substance (prostate-specific antigen) that causes an enlargement of your prostate.
Silodal-D 4 Combipack shows side effects such as headache, dizziness, diarrhoea, stuffy nose, abnormal ejaculation, and decreased sex drive. These side effects usually subside by themselves. However, consult your doctor if they remain for a long time or become severe.
Silodal-D 4 Combipack should be taken as instructed by your doctor. Your doctor will determine the dose and duration of treatment based on the severity of your condition. Avoid taking more or less than the prescribed dose. For the ease of remembering and better results, take it at the same time every day. Avoid discontinuing this medicine without your doctor's suggestion as your symptoms may reappear.
Silodal-D 4 Combipack should be avoided if you are allergic to it or have severe liver/kidney problems. Inform your doctor if you have low blood pressure, any other medical conditions, or taking any other medicines before starting the treatment with this medicine. Silodal-D 4 Combipack is not indicated for use in women and children.
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Substitutes
List of substitutes for Silodal-D 4 Combipack
Side effects
Major & minor side effects for Silodal-D 4 Combipack
Chills
Dizziness
Confusion
Headache
Diarrhoea
Stuffy nose
Abnormal ejaculation
Decreased sexual drive
Breast tenderness
Uses of Silodal-D 4 Combipack
What is it prescribed for?
Benign prostatic hyperplasia
Benign prostatic hyperplasia is a condition that causes enlargement of the prostate gland (a small gland in men that secretes fluid to nourish and transport the sperm). As the prostate surrounds the urethra (a tube that carries urine out of your body), an increase in the size of the prostate may lead to symptoms such as difficulty in urination, weak urinary stream, frequent urination, loss of bladder control, etc. Silodal-D 4 Combipack is used in the treatment of BPH.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for Silodal-D 4 Combipack to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which Silodal-D 4 Combipack remains active in your body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Avoid consumption of alcohol while taking Silodal-D 4 Combipack as it may increase the risk of dizziness, headache, lightheadedness, etc.Is this a habit forming medicine?
No habit-forming tendencies were reported for Silodal-D 4 Combipack.Can this medicine be taken during pregnancy?
Silodal-D 4 Combipack is not intended for use in women.Can this medicine be taken while breast-feeding?
Silodal-D 4 Combipack is not intended for use in women.
Allergy
Avoid taking Silodal-D 4 Combipack if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Severe kidney impairment
Silodal-D 4 Combipack is filtered from your body by the kidneys via urine. Hence, this medicine is not recommended for use if you have severe kidney problems. It may lead to the accumulation of this medicine in your body and increase the risk of side effects.
Severe liver impairment
Silodal-D 4 Combipack is broken down in your liver. Hence, this medicine is not recommended for use if you have severe liver problems as it may cause further liver damage.
Women and children
Silodal-D 4 Combipack is not indicated for use in women and children.
Warnings for special population
Pregnancy
Silodal-D 4 Combipack is not intended for use in women.
Breast-feeding
Silodal-D 4 Combipack is not intended for use in women.
General warnings
Cataract surgery
Cataract surgery is an eye surgery performed to replace the lens in your eyes with an artificial lens to correct the blurring of vision. Silodal-D 4 Combipack may lead to complications during cataract surgery. Hence, if you are taking this medicine, inform your doctor before undergoing surgery.
Low blood pressure
Silodal-D 4 Combipack may cause dilation of your blood vessels and lead to a decrease in blood pressure. Hence, this medicine should be used with caution if you have low blood pressure.
Blood donation
It is not recommended to donate blood until 6 months have passed after taking the last dose of Silodal-D 4 Combipack. This measure is taken to prevent the transfusion of blood to pregnant women.
Other medicines
Inform your doctor if you are taking any other medicines as they may interact with Silodal-D 4 Combipack and cause undesired effects.
Use in women and children
Silodal-D 4 Combipack is not indicated for use in women and children.
Driving or operating machines
Silodal-D 4 Combipack may cause a decrease in blood pressure leading to symptoms like dizziness. Avoid performing activities that require high mental alertness like driving vehicles or operating machines if you experience any symptoms during treatment with this medicine.
Missed Dose
If you miss a dose of Silodal-D 4 Combipack, take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the prescribed dose of Silodal-D 4 Combipack. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Avoid consumption of alcohol while taking Silodal-D 4 Combipack as it may increase the risk of dizziness, headache, lightheadedness, etc.
Interaction with Medicine
Amitriptyline
Erythromycin
Alprazolam
Nefazodone
Clotrimazole
Baclofen
Chlordiazepoxide
Conivaptan
Disease interactions
Kidney Disease
Silodal-D 4 Combipack should be used with caution if you have mild to moderate kidney problems as it may increase the risk of side effects. Your doctor may suggest tests to periodically monitor your kidney function and recommend dose adjustments based on your clinical condition.
Liver Disease
Silodal-D 4 Combipack should be used with caution if you have mild to moderate liver problems as this medicine may cause further liver damage. Your doctor may suggest tests to periodically monitor your liver function while taking this medicine.
Prostate cancer
Cancer of the prostate gland has similar symptoms to Benign Prostatic Hyperplasia. Hence, it is important to know if you have prostate cancer before starting the treatment. Your doctor may suggest tests to rule out the presence of prostate cancer before starting the treatment with Silodal-D 4 Combipack.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Silodal-D 4 Combipack as instructed by your doctor. Take this medicine for the recommended duration.
Avoid taking more than the prescribed dose as it may increase the risk of side effects.
Consult your doctor if your symptoms do not improve or become worse.
Avoid blood donation until 6 months of taking the last dose of Silodal-D 4 Combipack to prevent the transfusion of blood to pregnant women.
Miscelleneous
How it works
Silodal-D 4 Combipack is a combination of Silodosin and Dutasteride.
Silodosin works by relaxing the muscles of your bladder neck, urethra, and prostate. Thus, it relieves the symptoms of BPH.
Dutasteride blocks the production of a substance (Prostate-Specific Antigen (PSA)) that causes an enlargement of your prostate.
Legal Status
Classification
Category
Alpha-blockers, 5-alpha-reductase inhibitors, Genitourinary tract agents
Schedule
Schedule H
Drugs, H., 2021. Silodosin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 28 September 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - DUTASTERIDE capsule. [online] Available at: < [Accessed 28 September 2021].
CiplaMed. 2021. SILOFAST D Tablets. [online] Available at: < [Accessed 28 September 2021].
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 September 2021].
Allergan-web-cdn-prod.azureedge.net. 2021. [online] Available at: < [Accessed 6 September 2021].
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 28 September 2021].
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Information on this page was last updated on 28 Oct 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
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