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Ramistar-A (5/2.5 mg) Capsule
Manufactured byLupin Ltd.
ContainsAmlodipine (5 mg) + Ramipril (2.5 mg)
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Description
Ramistar-A (5/2.5 mg) Capsule is a combination of Amlodipine and Ramipril. It is used to treat hypertension (high blood pressure). This medicine works by relaxing the heart muscles and blood vessels. This relaxation promotes the smooth flow of blood in vessels and your heart pumps blood more efficiently.
Ramistar-A (5/2.5 mg) Capsule has some side effects like nausea, headache, upset stomach and change in taste. Avoid driving vehicles or operating machines and rise slowly from a sitting or lying position if you feel dizzy while on Ramistar-A (5/2.5 mg) Capsule treatment. Let your doctor know about any cough or throat irritation that does not go away.
Ramistar-A (5/2.5 mg) Capsule may cause swelling in your ankles; therefore, avoid sitting for long hours and try to keep the legs at the level or above your waist. Usually, these side effects are temporary. If any of these side effects do not resolve with time or get worse, seek a doctor's consultation at the earliest. Avoid taking this medicine if you are allergic to it.
Ramistar-A (5/2.5 mg) Capsule treatment should not be stopped all of a sudden as it can cause your blood pressure to rise, thereby increasing the risk of heart attack and stroke.
Ramistar-A (5/2.5 mg) Capsule is safer for you, when used after sharing your entire medical and medication history (especially Aliskiren) with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before taking Ramistar-A (5/2.5 mg) Capsule.
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Substitutes
List of substitutes for Ramistar-A (5/2.5 mg) Capsule
Side effects
Major & minor side effects for Ramistar-A (5/2.5 mg) Capsule
Blurred vision
Sweating
Dizziness
Unusual tiredness and weakness
Back pain
Chest tightness
Increased heartbeat
Cough
Diarrhoea
Vomiting
Swelling of ankles or feet
Difficulty in breathing
Redness of face, neck, arms and chest
Muscle pain
Heartburn
Acid or sour stomach
Stomach pain
Anxiety
Uses of Ramistar-A (5/2.5 mg) Capsule
What is it prescribed for?
Hypertension
Hypertension or high blood pressure is a condition in which the force exerted by your blood on blood vessel walls is high. Ramistar-A (5/2.5 mg) Capsule is used to reduce blood pressure.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of Ramistar-A (5/2.5 mg) Capsule can be observed within 1 to 2 hours of taking this medication.How long do the effects of this medicine last?
The effect of Ramistar-A (5/2.5 mg) Capsule lasts for an average duration of 24 hours.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during treatment with Ramistar-A (5/2.5 mg) Capsule due to the increased risk of side effects. Avoid performing any activities that require high mental alertness such as driving vehicles or operating machines.Is this a habit forming medicine?
Ramistar-A (5/2.5 mg) Capsule has no habit forming tendency.Can this medicine be taken during pregnancy?
Ramistar-A (5/2.5 mg) Capsule is not recommended for use during pregnancy as it can affect your foetus. Your doctor may prescribe a safer alternative based on your clinical condition.Can this medicine be taken while breast-feeding?
Ramistar-A (5/2.5 mg) Capsule is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
Allergy
Avoid taking Ramistar-A (5/2.5 mg) Capsule if you are allergic to this medicine. Seek medical attention if you see symptoms such as skin rash, swelling ( of face, lips, tongue, etc.), breathing difficulty, etc.
Aliskiren
Combined use of Ramistar-A (5/2.5 mg) Capsule and Aliskiren is not recommended if you have diabetes and/or kidney impairment with CrCl less than 60 ml/min. Combined use of these medicines may increase the risk of side effects.
Liver disease
Ramistar-A (5/2.5 mg) Capsule is converted into its active form by your liver. The presence of the liver disease may impair the conversion of this medicine into its active form thus leading to the accumulation of this medicine in your liver. This accumulation may worsen your liver condition. Hence, Ramistar-A (5/2.5 mg) Capsule is not recommended for use if you have active liver diseases.
Warnings for special population
Pregnancy
Ramistar-A (5/2.5 mg) Capsule is not recommended for use during pregnancy as it can affect your foetus. Your doctor may prescribe a safer alternative based on your clinical condition.
Breast-feeding
Ramistar-A (5/2.5 mg) Capsule is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Hypotension
Symptomatic hypotension (low blood pressure) may occur in the presence of volume depletion (excess loss of salt and fluid leading to reduced fluid volume) or when treated with other medicines used in the treatment of high blood pressure. Correct this condition before initiating treatment with Ramistar-A (5/2.5 mg) Capsule.
Hyperkalemia
Ramistar-A (5/2.5 mg) Capsule may increase the potassium levels in your blood (hyperkalemia). It should be used if you have hyperkalemia and potassium levels should be monitored regularly. Avoid potassium-rich foods (potatoes, bananas) and potassium supplements during treatment with this medicine.
Use in children
Ramistar-A (5/2.5 mg) Capsule is not recommended for use in children and adolescents less than 18 years of age as the safety and efficacy of use are not clinically established.
Cough
Ramistar-A (5/2.5 mg) Capsule may cause a persistent nonproductive cough. It is resolved when the medicine is discontinued.
Aortic stenosis
Aortic stenosis is the narrowing of the valves of your heart that regulate the blood flow between the heart chambers. Ramistar-A (5/2.5 mg) Capsule should be used with caution if you have aortic stenosis.
Kidney disease
Ramistar-A (5/2.5 mg) Capsule may cause azotemia (elevated levels of urea and other nitrogen compounds in your blood) if you have a history of severe kidney disease. Your doctor will closely monitor your kidney function or adjust the dose to use this medicine safely.
Driving and operating machines
Ramistar-A (5/2.5 mg) Capsule may cause dizziness and a decrease in blood pressure. Avoid performing any activities that require high mental alertness like driving vehicles or operating machines.
Missed Dose
If you missed a dose of Ramistar-A (5/2.5 mg) Capsule, take it as soon as you remember. If the next dose timing is near, skip the missed dose. Take your next dose at your usual time. Do not double the dose.
Overdose
If you suspect that you might have taken an overdose of Ramistar-A (5/2.5 mg) Capsule, seek medical attention at the earliest.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with Ramistar-A (5/2.5 mg) Capsule due to the increased risk of side effects. Avoid performing any activities that require high mental alertness such as driving vehicles or operating machines.
Interaction with Medicine
Itraconazole
Losartan
Corticosteroids
Rifampicin
Insulin
Nonsteroidal anti-inflammatory medicines
Disease interactions
Angioedema
Use of Ramistar-A (5/2.5 mg) Capsule is not recommended if you have a history of angioedema (swelling in the lower layer of your skin). In such cases, you may be at an increased risk of angioedema while receiving the treatment. Consult with your doctor if you have any concerns.
Cardiogenic shock
Ramistar-A (5/2.5 mg) Capsule is not recommended for use in case of cardiogenic shock ( your heart suddenly stops pumping enough blood to the body) because it may worsen your heart condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Ramistar-A (5/2.5 mg) Capsule due to the increased risk of adverse effects such as dizziness, muscle pain, fever and chills, headache, swelling of hands and feet, vomiting, skin rash, etc.
Lab interactions
Information not available.
Take Ramistar-A (5/2.5 mg) Capsule with or without food. It can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough or throat irritation that does not go away.
It may increase the level of potassium in the blood. Avoid taking potassium supplements and potassium-rich foods such as bananas and broccoli.
Do not crush, break or chew the tablet in your mouth.
Miscelleneous
How it works
Ramistar-A (5/2.5 mg) Capsule is a combination of Amlodipine and Ramipril.
Amlodipine relaxes your heart muscles and blood vessels.
Ramipril relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing blood pressure.
Legal Status
Classification
Category
Calcium channel blocking agents, Angiotensin converting enzyme inhibitors, ACE inhibitors with calcium channel blocking agents, Antihypertensive combinations
Schedule
Schedule H
Medicines.org.uk. 2021. Ramipril 2.5mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 September 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - ramipril- Ramipril capsule. [online] Available at: < [Accessed 17 August 2021].
Medicines.org.uk. 2021. Amlodipine 5mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 September 2021].
Products.sanofi.in. 2021. [online] Available at: < [Accessed 1 September 2021].
Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 1 September 2021].
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Information on this page was last updated on 1 Sep 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.