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Pulmonext Kit
Manufactured byMSN LABORATORIES LTD
ContainsAmbrisentan (5 mg) + Tadalafil (20 mg)
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Description
Pulmonext Kit is used in the treatment of pulmonary arterial hypertension (a condition characterized by high blood pressure inside the blood vessels that carry the blood from the heart to your lungs).
Pulmonext Kit is a combination of Ambrisentan and Tadalafil. Ambrisentan works by stopping the action of a chemical substance in your body that causes narrowing of your blood vessels and prevents normal blood flow. Tadalafil works by relaxing the blood vessels in your lungs and allowing blood to flow more easily.
Pulmonext Kit may cause common side effects such as headache, low red blood cell count, abdominal pain, constipation, chest pain, nasal congestion, etc. Consult your doctor if these symptoms persist or worsen.
Pulmonext Kit should be taken exactly as directed by your doctor. Take it at the same time every day to maintain a constant level of this medicine in your body.
Pulmonext Kit should be avoided if you are allergic to it. Inform your doctor if you have a history of heart, eye or ear problems before beginning treatment with this medicine. Close evaluation with respect to your current medicines is necessary to avoid any undesired side effects.
Pulmonext Kit is not recommended for use in children below 18 years of age. If you are pregnant or breastfeeding, or are planning a pregnancy, consult your doctor before taking this medication.
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Substitutes
List of substitutes for Pulmonext Kit
Side effects
Major & minor side effects for Pulmonext Kit
Anaemia (Low red blood cell count)
Headache
Abdominal pain
Constipation
Flushing (reddening of the skin)
Chest pain and discomfort
Nasal congestion
Dizziness
Syncope (loss of consciousness)
Hypotension (low blood pressure)
Increased liver enzyme levels
Uses of Pulmonext Kit
What is it prescribed for?
Pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a condition characterized by high blood pressure inside the blood vessels that carry the blood from the heart to your lungs. Symptoms may include shortness of breath, dizziness, and chest pain/pressure. Pulmonext Kit is used in the treatment of PAH.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Pulmonext Kit begins to show its effect within 30 to 45 minutes after intake.How long do the effects of this medicine last?
Pulmonext Kit remains effective for an approximate duration of three days after intake.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during treatment with Pulmonext Kit due to the increased risk of low blood pressure. Inform your doctor if you experience any symptoms of headache, dizziness, lightheadedness, fainting, changes in your pulse or heart rate.Is this a habit forming medicine?
No habit-forming tendencies have been reported with Pulmonext Kit.Can this medicine be taken during pregnancy?
Pulmonext Kit may cause severe side effects in your developing foetus and is not recommended for use during pregnancy.Can this medicine be taken while breast-feeding?
It is not known if Pulmonext Kit passes into breastmilk. This medicine is not recommended for use during breastfeeding.
Allergy
Avoid Pulmonext Kit if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Loss of vision
Pulmonext Kit may affect your vision and is not recommended if you have lost vision in one of your eyes.
Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a chronic (long-term), progressive condition that affects your lungs and may cause fibrosis (scarring) in your lungs. This may result in breathing difficulties. Pulmonext Kit is not recommended if you have idiopathic pulmonary fibrosis due to the increased risk of worsening your condition.
Warnings for special population
Pregnancy
Pulmonext Kit may cause severe side effects in your developing foetus and is not recommended for use during pregnancy.
Breast-feeding
It is not known if Pulmonext Kit passes into breastmilk. This medicine is not recommended for use during breastfeeding.
General warnings
Use in children
Pulmonext Kit is not recommended for use in children below 18 years of age due to a lack of safety and efficacy studies.
Driving or Operating machines
Pulmonext Kit may cause dizziness and hypotension (low blood pressure). Do not drive vehicles or operate machines if you experience any symptoms that may affect your mental alertness after taking this medicine.
Other medicines
Pulmonext Kit may interact with other medicines and may cause undesired side effects. Inform your doctor about your current medicines including any herbs or supplements before taking this medicine.
Anaemia
Pulmonext Kit may lower the haemoglobin (a protein present in your red blood cells) and haematocrit levels (a measure of the percentage of your red blood cells) in your body. This may increase your risk of anaemia (low red blood cell count). Your haemoglobin level and red blood cell count needs to be closely monitored.
Fluid retention
Pulmonext Kit may increase your risk of fluid retention (accumulation of fluid in your body tissues and cavities). Symptoms may include swelling of affected parts of your body (feet, ankles and hands), rapid weight gain (over a few days or weeks), etc. Inform your doctor if you experience such symptoms.
Fertility
Pulmonext Kit may lower your sperm cell count and affect your fertility. Hence it is recommended to avoid planning a pregnancy while on treatment with this medicine.
Women of childbearing potential
Pulmonext Kit may cause severe side effects in the developing foetus. Hence it is recommended to avoid pregnancy while on treatment with Pulmonext Kit and for one month after discontinuation of treatment with this medicine.
Missed Dose
Try not to skip a dose of Pulmonext Kit. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.
Overdose
Do not take more than the prescribed dose. Contact your doctor if you suspect an overdose with Pulmonext Kit.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with Pulmonext Kit due to the increased risk of low blood pressure. Inform your doctor if you experience any symptoms of headache, dizziness, lightheadedness, fainting, changes in your pulse or heart rate.
Interaction with Medicine
Azole antifungal agents
Antihypertensives
Riociguat
Nitrates
Cyclosporine
Disease interactions
Heart Disease
Pulmonext Kit should be used with caution if you have pre-existing heart problems due to the increased risk of severe side effects. Your blood pressure, electrocardiogram (ECG), electrolyte levels need to be closely monitored to assess your heart function while on treatment with this medicine.
Eye disorder
Pulmonext Kit may affect your vision and increase your risk of vision loss. Inform your doctor if you experience any changes in your vision while on treatment with this medicine.
Hearing impairment
Pulmonext Kit may increase your risk of side effects such as tinnitus (a ringing sensation in your ears), hearing loss, etc. Inform your doctor if you experience a sudden decrease or loss of hearing while on treatment with this medicine.
Priapism
Pulmonext Kit may increase your risk of priapism, a condition with a prolonged, painful erection of your penis. Inform your doctor if you experience an erection lasting longer than four hours (with/without pain) while on treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Pulmonext Kit with or without food. Do not take more or less than the prescribed dose. Do not stop the use of this medicine without consulting your doctor as it may worsen your condition.
Pulmonext Kit may cause anaemia (low red blood cell count). Your red blood cell count needs to be closely monitored.
Avoid alcohol consumption while on treatment with Pulmonext Kit as it may affect your blood pressure.
Do not drive vehicles or operate machines if you experience any symptoms that may affect your alertness after taking Pulmonext Kit.
Miscelleneous
How it works
Pulmonext Kit is a combination of Ambrisentan and Tadalafil.
Ambrisentan works by stopping the action of endothelin, a chemical substance in your body that causes narrowing of your blood vessels and prevents normal blood flow. Blocking of endothelin results in improved blood flow to your lungs.
Tadalafil works by relaxing the blood vessels in your lungs and allowing blood to flow more easily.
Legal Status
Classification
Category
Antihypertensive combinations
Schedule
Schedule H
CiplaMed. 2021. ENDOBLOC T Kit. [online] Available at: < [Accessed 7 December 2021].
Drugs, H., 2021. Ambrisentan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 December 2021].
Drugs, H., 2021. Tadalafil: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 December 2021].
Related Questions
Information on this page was last updated on 24 Dec 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
₹1450
20 TABLET ( 20 / STRIP )