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Polyclav (400/57 mg) Dry Syrup

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsAmoxycillin (400 mg) + Clavulanic Acid (57 mg)
CURRENTLY UNAVAILABLE

Description

Polyclav (400/57 mg) Dry Syrup is a combination of Amoxycillin and Clavulanic acid. Polyclav (400/57 mg) Dry Syrup is used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, teeth, and urinary tract. It is also used to treat multidrug-resistant Tuberculosis. This medicine is generally meant to be used in children. However, your doctor may prescribe this medicine to you if you cannot swallow the tablet or capsule. Polyclav (400/57 mg) Dry Syrup shows common side effects like nausea, vomiting, stomach pain, and skin rash. Usually, these side effects are self-limiting. Consult the doctor at the earliest if any of these side effects persist or bothers your child. Before giving this medicine to your child, inform your doctor if your child is allergic to any antibiotics. Polyclav (400/57 mg) Dry Syrup can be given to your child with food as it improves absorption and decreases the risks of stomach upset. Your child's doctor will decide the dose and frequency based on the severity of infection, body weight and age of your child. Also, ensure that you complete the course of treatment even if your child starts feeling better after taking a few doses. Polyclav (400/57 mg) Dry Syrup is safe for your child, however, do share your child’s entire medical history with the doctor, including any previous episode of allergy, heart problem, a blood disorder, birth defects, lung problem, stomach or intestinal problem, skin disorder, liver and kidney problems. This information is critical as it can help your paediatrician in planning an overall treatment and dose adjustments for your child.
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Substitutes

List of substitutes for Polyclav (400/57 mg) Dry Syrup

Side effects

Major & minor side effects for Polyclav (400/57 mg) Dry Syrup

Allergic Skin Reaction

Diarrhoea

Fever

Skin yellowing

Easy bruising and bleeding

Tooth discoloration

Nausea or vomiting

Swelling of face, lips, eyelids, tongue, hands and feet

Black or tarry stools

Muscle or joint pain

Sleeplessness

Uses of Polyclav (400/57 mg) Dry Syrup

What is it prescribed for?

Acute otitis media

Acute Otitis media (AOM), is an infection of the middle ear (the area behind the eardrum), common in infants and young children. Polyclav (400/57 mg) Dry Syrup is used to treat acute otitis media caused by bacteria.

Sinusitis

Sinusitis is the swelling of membranes that line the nose and surrounding sinuses. It is often caused by bacteria and sometimes, viruses and fungi. It is characterized by a stuffed nose and pain or pressure behind the eyes, nose, cheeks, or forehead. Polyclav (400/57 mg) Dry Syrup is used to treat bacterial sinusitis in children.

Lower respiratory tract infection

Polyclav (400/57 mg) Dry Syrup is used to treat Pneumonia and Bronchitis in children. Pneumonia is an infection of the air sacs in the lungs (either single or both lungs). It can be bacterial and viral. This medicine is used to treat pneumonia caused by bacteria. Bronchitis is the swelling and irritation of bronchial tubes that regulates air passage in the lungs. It is used to treat bronchitis caused by bacteria.

Skin infections

Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Polyclav (400/57 mg) Dry Syrup is used to treat all skin infections including abscesses caused by bacteria in children.

Pharyngitis/Tonsilitis

Pharyngitis and tonsillitis are infections that cause swelling and soreness in the throat and tonsils. Polyclav (400/57 mg) Dry Syrup is used to treat pharyngitis, tonsillitis, and/or pharyngotonsillitis (a condition where the infection affects both the throat and the tonsils) in children.

Urinary tract infection

An infection in any part of the urinary system (kidneys, bladder, ureters, or urethra) is called a urinary tract infection (UTI). UTIs are caused by bacteria and in some cases, viruses or fungi. Polyclav (400/57 mg) Dry Syrup is used to treat urinary tract infections caused by bacteria in children.

Multidrug resistant Tuberculosis

Multidrug-resistant Tuberculosis is caused by TB bacteria that is resistant to at least isoniazid and rifampin, the two most potent TB medicines. Polyclav (400/57 mg) Dry Syrup is used to treat tuberculosis in children, which is resistant to first-line TB medicines.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    Polyclav (400/57 mg) Dry Syrup starts working within 1-2 hours of administration.

  • How long do the effects of this medicine last?

    The effect of Polyclav (400/57 mg) Dry Syrup lasts for an average duration of 6-8 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    Polyclav (400/57 mg) Dry Syrup has no habit-forming tendency.

  • Can this medicine be taken during pregnancy?

    Polyclav (400/57 mg) Dry Syrup is only recommended for use in children.

  • Can this medicine be taken while breast-feeding?

    Polyclav (400/57 mg) Dry Syrup is only recommended for use in children.

Allergy

Avoid administration of Polyclav (400/57 mg) Dry Syrup if your child is allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Cholestasis

Polyclav (400/57 mg) Dry Syrup should be avoided if your child has Cholestasis (a condition where the normal flow of bile from the liver is interrupted).

Liver dysfunction

Avoid using Polyclav (400/57 mg) Dry Syrup if your child has a history of liver problems associated with the use of this medicine or any other antibiotics.

Warnings for special population

Pregnancy

Polyclav (400/57 mg) Dry Syrup is only recommended for use in children.

Breast-feeding

Polyclav (400/57 mg) Dry Syrup is only recommended for use in children.

General warnings

Diarrhoea

Polyclav (400/57 mg) Dry Syrup can cause diarrhoea because it may also kill the helpful bacteria in your child's stomach or intestine. Seek emergency medical help if your child gets diarrhoea by using this medicine.

Antibiotic resistance

Finish the entire course of treatment with Polyclav (400/57 mg) Dry Syrup, even if your child's condition gets better to avoid antibiotic resistance (bacteria develops the ability to overcome the antibiotic's ability to kill them).

Liver disease

Polyclav (400/57 mg) Dry Syrup may increase liver enzyme levels and cause liver swelling. If your child has liver problems, caution should be maintained while using Polyclav (400/57 mg) Dry Syrup due to the risk of liver damage. Your doctor may adjust the dose of this medicine and may closely monitor your child's liver functioning if required, based on the clinical conditions of your child.

Form of medication

Polyclav (400/57 mg) Dry Syrup is normally used for children. However, adultss who are unable to chew or swallow the solid form can use the liquid form under their doctor's supervision.

Missed Dose

If you forget to give a Polyclav (400/57 mg) Dry Syrup dose to your child, make sure that you remember to give your next dose on time. Do not give two doses together to make up for a forgotten dose.

Overdose

Never give Polyclav (400/57 mg) Dry Syrup more than the prescribed dose. If you suspect that you might have given an overdose of this medicine and observing difficulty in the child, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Live vaccines

Disease interactions

Colitis

Polyclav (400/57 mg) Dry Syrup can kill the helpful bacteria in your child's stomach or intestine and lead to diarrhoea. Therefore use this medicine with extreme caution in children with colitis (swelling of the inner lining of the colon).

Kidney diseases

Children with kidney problems need special consideration while taking Polyclav (400/57 mg) Dry Syrup due to the risk of kidney damage. Dose adjustment will be done by your doctor based on the clinical condition of your child.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Give Polyclav (400/57 mg) Dry Syrup to your child with food to decrease the risk of stomach upset. Ensure that you complete the entire course of Polyclav (400/57 mg) Dry Syrup as abrupt stopping may cause recurrence of the infection, or cause another infection. Your child may have a bitter taste in the mouth after taking Polyclav (400/57 mg) Dry Syrup. Eating citrus fruits or fruit juices may help. Encourage your child to drink plenty of water in case diarrhoea develops as a side effect. Never give Polyclav (400/57 mg) Dry Syrup unless prescribed by the doctor. You must also never share your child’s medicine with anyone else even if they show similar symptoms. Avoid giving Polyclav (400/57 mg) Dry Syrup to treat the common cold and flu-like symptoms caused by viruses. Never save Polyclav (400/57 mg) Dry Syrup for future. It cannot be said whether the same medicine will work on future infections. Discard the medicine if the seal is broken or the appearance of the liquid changes. Stop Polyclav (400/57 mg) Dry Syrup immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to the doctor without any delay.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

Effect on sleep is not established

How it works

Polyclav (400/57 mg) Dry Syrup is a combination of Amoxycillin and Clavulanic acid. Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines.

Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].

https://medlineplus.gov/druginfo/meds/a685024.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=909c85de-c076-4444-b63c-cd8bdc556f36>

Ca.gsk.com. 2021. [online] Available at: < [Accessed 31 May 2021].

https://ca.gsk.com/media/590864/clavulin.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clavulanic-acid>

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>

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Information on this page was last updated on 26 Oct 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.