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Pentotas D Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsDomperidone (10 mg) + Pantoprazole (40 mg)
CURRENTLY UNAVAILABLE

Description

Pentotas D Tablet is a combination of Domperidone and Pantoprazole. It is used in the treatment of peptic ulcers (sores in the stomach that form due to excess acid) and gastroesophageal reflux disease (a condition where the stomach acid flows back into the food pipe and damages it). These conditions lead to symptoms such as heartburn, discomfort in the stomach, vomiting sensation, and difficulty in swallowing food. Pentotas D Tablet reduces the sensation of nausea and decreases the production of stomach acid. Thus, it helps to heal ulcers. Pentotas D Tablet shows some common side effects like headache, dry mouth, stomach pain/discomfort, diarrhoea, and dizziness. Consult your doctor if these side effects bother you. Pentotas D Tablet should be taken one hour before your meal. The dosage and duration of this medicine will be decided by your doctor. You should take this medicine for the complete duration prescribed by your doctor. If you stop this medicine early, your symptoms may come back or your condition may worsen. Pentotas D Tablet may interact with other medications. Inform your doctor if you have liver, kidney, heart, and/or bone problems and if you are taking any medications. Do not take Pentotas D Tablet if you are allergic to it. This medicine may cause dizziness. Do not drive or operate heavy machines while you are taking Pentotas D Tablet. Pentotas D Tablet is not recommended for children below 12 years of age due to limited safety and efficacy data. Consult your doctor if you are pregnant, or are breastfeeding while taking this medicine.
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Side effectsConcernsUsage

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Substitutes

List of substitutes for Pentotas D Tablet

Side effects

Major & minor side effects for Pentotas D Tablet

Headache

Altered sense of taste

Diarrhea

Unusual tiredness and weakness

Skin Rash

Difficulty in breathing

Disrupted menstrual cycle

Breast pain and tenderness

Dry mouth

Swelling of ankles or feet

Dark urine

Dizziness

Stomach pain

Visual disturbances

Uses of Pentotas D Tablet

What is it prescribed for?

Gastroesophagal reflux disease

Gastroesophageal Reflux Disease (GERD) is a disease that occurs when stomach acid frequently flows back into the food pipe. Heartburn, stomach upset, difficulty in swallowing food, and nausea are the main symptoms of GERD. Pentotas D Tablet helps in the treatment of GERD by decreasing stomach acid production and stopping the sensation of nausea.

Peptic Ulcer

Peptic ulcers are sores (damaged and painful areas) on the lining of the food pipe, stomach, and small intestine. They occur due to excess acid production in your stomach. Heartburn and stomach upset are the main symptoms of peptic ulcers. Pentotas D Tablet helps in the treatment of peptic ulcers by decreasing stomach acid production.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Pentotas D Tablet is seen within 30 to 60 minutes.

  • How long do the effects of this medicine last?

    After administration, the effect of Pentotas D Tablet remains in your body for an average duration of 24 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit forming tendencies were reported for Pentotas D Tablet.

  • Can this medicine be taken during pregnancy?

    Pentotas D Tablet is usually not recommended in pregnant women. Consult your doctor if you are pregnant. Your doctor may prescribe another suitable alternative.

  • Can this medicine be taken while breast-feeding?

    Pentotas D Tablet may pass into breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Pentotas D Tablet if you are allergic to it. Inform your doctor if you have a history of allergy to this medicine. Seek immediate medical attention if you notice any symptoms such as skin rashes, itching/swelling of the face/tongue/throat, breathing difficulty, etc.

Prolactinoma

Prolactinoma is a tumour of the pituitary gland which leads to an increase in prolactin (a hormone responsible for milk production in lactating women). It occurs more often in women compared to men. The symptoms in women are infertility, irregular periods, and acne. Avoid taking Pentotas D Tablet as it worsens your condition.

Heart diseases

Pentotas D Tablet may cause irregular heartbeat. Hence, this medicine is not recommended if you have pre-existing heart conditions like congestive heart failure (a condition in which your heart is not able to pump sufficient blood throughout the body), QT prolongation (heart muscle takes longer than normal to recharge between a heartbeat), etc., as it may worsen your health condition.

Moderate to severe liver impairment

Pentotas D Tablet is broken down in the liver.This tablet is not recommended if you have moderate to severe liver problems.

Warnings for special population

Pregnancy

Pentotas D Tablet is usually not recommended in pregnant women. Consult your doctor if you are pregnant. Your doctor may prescribe another suitable alternative.

Breast-feeding

Pentotas D Tablet may pass into breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.

General warnings

Other medicines

Inform your doctor about the use of all your medicines including any herbs and supplements as Pentotas D Tablet may interact with other medications and cause severe side effects.

Use in children

Avoid the use of Pentotas D Tablet below 12 years of age as there is no safety and efficacy established.

Use in elderly

Pentotas D Tablet should be used with caution in elderly people. The activity of the liver and kidney decreases with age and this leads to an increased risk of severe side effects while taking this medicine.

Prolactin imbalance

Using Pentotas D Tablet for a long time or at higher doses increases the level of prolactin hormone in your body. This may lead to side effects like infertility and irregular periods. The increased levels of prolactin may fall to normal after discontinuation of the medicine.

Driving or operating machines

Pentotas D Tablet may cause visual disturbances or dizziness. Hence, you should avoid driving vehicles and operating heavy machines after taking this medicine until you know how this medicine affects you.

Effect on the heart

Pentotas D Tablet can increase the risk of abnormal heartbeat or other heart problems. The risk may be higher if you are older than 60 years or if you are taking a higher dose of this medicine.

Missed Dose

Try not to skip the dose of Pentotas D Tablet. In case you missed a dose, take it as soon as you remember. If the delay is more than 12 hours, skip the dose. Do not take a double dose.

Overdose

You should not take more than the prescribed dose. In case of an overdose, seek immediate medical attention or contact your doctor.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Ketoconazole

Methotrexate

Warfarin

Nelfinavir

Digoxin

Disease interactions

Osteoporosis

Osteoporosis is a condition in which bones become weak. This medicine decreases calcium absorption in your body leading to a deficiency of calcium required to maintain bone density. Hence, long-term use of Pentotas D Tablet is not recommended as it can lead to decreased bone strength. Your need to regularly monitor your bone health and mineral status while you take this medicine, particularly on long-term use.

Hypomagnesemia

Long-term use of Pentotas D Tablet may result in hypomagnesemia (low magnesium levels in your blood). Inform your doctor if you experience any symptoms such as dizziness, irregular heartbeat, shivering, muscle pain, seizures (fits), etc. You may have to check magnesium levels in the blood at regular intervals. Consult your doctor if you have any concerns.

Kidney Disease

If you have severe kidney problems use Pentotas D Tablet with caution as prolonged use may increase the accumulation of this medicine in your body.

Food interactions

Information not available.

Lab interactions

Tetrahydrocannabinol (THC)

There may be a false-positive test of urine screening for tetrahydrocannabinol if you are taking Pentotas D Tablet. Inform your doctor or lab technician about the use of this medicine before the lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Pentotas D Tablet one hour before meal. Swallow it with an adequate amount of water. Do not chew or crush the tablet. Avoid taking more than the prescribed dose. Complete the course of treatment as directed by your doctor. Avoid taking food and drinks such as peppermint, chocolates, spicy food, coffee, alcoholic drinks, etc. as it may worsen your symptoms. Avoid driving and operating heavy machines as this medicine may cause visual disturbances and dizziness.

Miscelleneous

To be taken before food

To be taken as instructed by doctor

Causes sleepiness

How it works

Pentotas D Tablet is a combination of two medicines; Domperidone and Pantoprazole. This combination works effectively in reducing stomach acid and preventing vomiting. Domperidone works by increasing the movement of the food through your stomach into the intestine thus, it prevents vomiting. Pantoprazole works by decreasing the production of acid in your stomach.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antiemetics, Proton pump inhibitors

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Domperidone. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone>

Pubchem.ncbi.nlm.nih.gov. 2021. Pantoprazole. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Pantoprazole>

Medicines.org.uk. 2021. Pantoprazole 40 mg gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 10 August 2021].

https://www.medicines.org.uk/emc/product/484/smpc#gref>

Medicines.org.uk. 2021. Domperidone 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 August 2021].

https://www.medicines.org.uk/emc/product/556/smpc#gref>

nhs.uk. 2021. Domperidone: anti-sickness medicine used to treat nausea and vomiting. [online] Available at: < [Accessed 6 August 2021].

https://www.nhs.uk/medicines/domperidone/>

Medicineindia.org. 2021. Pantoprazole + Domperidone Pharmacology & Usage Details | Medicine India. [online] Available at: < [Accessed 6 August 2021].

https://www.medicineindia.org/pharmacology-for-generic/1360/pantoprazole-domperidone>

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Information on this page was last updated on 16 Sep 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.