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Pedispan Syrup

Manufactured byABYSS PHARMA PVT LTD
ContainsParacetamol (125 mg/5 ml) + Promethazine (5 mg/5 ml)
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Description

Pedispan Syrup is used for the treatment of fever and minor body pain due to common cold in children. It also provides relief from allergic symptoms due to common colds like runny nose, sneezing, cough, redness of the nose, and watery eyes in children. Pedispan Syrup stops the release of a chemical called prostaglandin that causes pain and fever and also histamine responsible for causing allergic symptoms. Side effects of Pedispan Syrup are dizziness, sleepiness, diarrhoea, nausea or vomiting. However, Pedispan Syrup is banned for use in India due to its severe adverse effects. Pedispan Syrup can be taken with or without food. Children with a sensitive stomach should take this medicine with food to prevent stomach discomfort. Administer Pedispan Syrup at around the same time every day. If your child vomits this medicine within 30 minutes of administering it, then repeat the dose again.

Substitutes

List of substitutes for Pedispan Syrup

Side effects

Major & minor side effects for Pedispan Syrup

Nausea or Vomiting

Mouth ulcers

Bloody and cloudy urine

Dizziness

Skin rash

Drowsiness

Loss of strength

Loss of appetite

Increased sensitivity of the skin to sunlight

Uses of Pedispan Syrup

What is it prescribed for?

Fever

Fever is usually not something to worry about unless if the body temperature is very high or lasts for longer. It can be a sign of several health conditions. Pedispan Syrup is used to relieve fever, especially those that are associated with a common cold.

Common Cold

A common cold is one of the most common viral infection of the nose and throat. It is a self-recovering condition and symptoms usually resolve within two weeks. Pedispan Syrup is used to treat allergic symptoms due to common colds like runny nose, sneezing, cough, redness of the nose, and watery eyes.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    Pedispan Syrup starts its action within 20-30 minutes of administration.
  • How long do the effects of this medicine last?

    Pedispan Syrup makes the child feel better for about 12 hours.
  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?

    No habit forming tendencies were reported for Pedispan Syrup.
  • Can this medicine be taken during pregnancy?

    Pedispan Syrup is not recommended for use in pregnant women.
  • Can this medicine be taken while breast-feeding?

    Pedispan Syrup is not recommended for use in breastfeeding women.

Allergy

Avoid using Pedispan Syrup in children who are previously allergic to it. Seek immediate medical attention if there are any serious allergic symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or breathing difficulties.

Severe liver impairment

Children with liver diseases need special dose consideration for Pedispan Syrup. This medicine gets converted to its active form in the liver. Therefore, in large amounts of this medicine, more active forms are formed which can damage the liver. The use of this medicine is generally not recommended in children with severe liver diseases because it can further increase the risk of liver damage.

Warnings for special population

Pregnancy

Pedispan Syrup is not recommended for use in pregnant women.

Breast-feeding

Pedispan Syrup is not recommended for use in breastfeeding women.

General warnings

Skin rash

Pedispan Syrup may cause serious skin allergies without any warnings. These events may be fatal in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor immediately. The treatment should be discontinued if these symptoms appear.

Chronic malnutrition

Malnutrition can increase the risk of Pedispan Syrup toxicity in the body. Dose adjustment should be done based on body weight in children.

Missed Dose

Administer the missed dose of Pedispan Syrup as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double the dose to make up for the missed dose.

Overdose

Seek medical emergency in case of an overdose with Pedispan Syrup.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Chlorpheniramine

Disease interactions

Liver Disease

Children with liver diseases need special dose consideration while using Pedispan Syrup. The conversion of Pedispan Syrup to its active form happens in the liver. Overdose can produce more active forms and leads to liver damage.

Asthma

Children with asthma may experience allergic reactions while using Pedispan Syrup. Hence it is not recommended for use in children with asthma, especially those who had experienced allergic reactions with the use of this medicine.

Heart disease

Long-term use of Pedispan Syrup may increase the risk of irregular heartbeat in children with pre-existing heart conditions or heart rhythm disorders. Heart function needs to be monitored in such patients.

Food interactions

Information not available.

Lab interactions

Information not available.
Administer Pedispan Syrup with or without food. Children with a sensitive stomach should be given this medicine with food to prevent stomach irritation. Never give more than the prescribed dose. Administer this suspension at around the same time daily. If your child vomits this medicine within 30 minutes of administering it, then repeat the dose again.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works

Paracetamol works by decreasing the severity of pain signals to the brain. It also stops the release of chemicals called prostaglandins, that increase pain, and body temperature. Promethazine works by stopping the binding of histamine to its receptor and thus helps in relieving the symptoms.

Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Analgesics, Antihistamines

Schedule

Schedule H

Drugbank.ca. 2021. Promethazine | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB01069>

Drugbank.ca. 2021. Acetaminophen | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB00316>

Pubchem.ncbi.nlm.nih.gov. 2021. Acetaminophen. [online] Available at: < [Accessed 26 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Pubchem.ncbi.nlm.nih.gov. 2021. Promethazine. [online] Available at: < [Accessed 26 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Promethazine>

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Information on this page was last updated on 27 May 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.