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Parkin Plus Tablet
Manufactured byMICRO LABS LTD
ContainsTrifluoperazine (5 mg) + Trihexyphenidyl (2 mg)
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Description
Parkin Plus Tablet is a combination medicine which may be used for the treatment of Schizophrenia, Parkinson's disease, Anxiety, and extrapyramidal symptoms caused by other medicines. This medicine is not recommended for use in patients below 18 years of age.
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Substitutes
List of substitutes for Parkin Plus Tablet
Side effects
Major & minor side effects for Parkin Plus Tablet
Fever
Dizziness
Headache
Confusion
Sleeplessness
Dry mouth
Nausea
Vomiting
Abdominal pain
Constipation
Loss of appetite
Difficulty in passing urine
Skin rash
Uses of Parkin Plus Tablet
What is it prescribed for?
Schizophrenia
This medicine may be used in the treatment of schizophrenia, a nervous system disorder that affects the patient's ability to think, feel, and behave. It is characterized by symptoms such as delusions, hallucinations, disinterests, difficulty with speech, etc.
Anxiety
This medicine may be used in the treatment of anxiety, which is characterized by symptoms such as uneasiness, nervousness, fear, persistent worry, etc.
Parkinson's disease
This medicine may be used in the treatment of Parkinson's disease, which is a central nervous system disorder characterized by trembling of hands, arms, and face, slowness of movement and stiffness of limbs.
Drug-induced Extrapyramidal Symptoms
This medicine may be used in the treatment of extrapyramidal symptoms like restlessness, muscle spasms, and contractions caused by medicines belongs to class phenothiazines, thioxanthenes, and butyrophenones.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of this medicine can be observed within 1 hour of administration of the dose.How long do the effects of this medicine last?
The effect of this medicine lasts for an average duration of 6 to 12 hours.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during the treatment with this medicine as it may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.Is this a habit forming medicine?
No habit-forming tendencies were reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to trifluoperazine, trihexyphenidyl, or any other inactive ingredients present in the formulation.
CNS Depression
This medicine is not recommended for use in patients suffering from severe central nervous system depression or coma due to the increased risk of worsening of the patient's condition.
Narrow-angle glaucoma
This medicine is not recommended for use in patients suffering from narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Seizures
This medicine should be used with extreme caution in patients suffering from seizure disorder due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Use in Children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Driving or Operating machinery
Use of this medicine may cause symptoms such as dizziness, blurred vision, confusion, drowsiness, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Dementia
This medicine is not recommended for use in patients suffering from dementia due to the increased risk of serious adverse effects including death. This risk is especially higher in the elderly patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Neuroleptic Malignant Syndrome
This medicine may cause Neuroleptic Malignant Syndrome (NMS) in patients who discontinued the treatment or reduced the daily recommended dose. Any symptoms of fever, muscle rigidity, altered mental status should be informed to the doctor.
Tardive dyskinesia
This medicine is not recommended for use in patients with tardive dyskinesia which is an involuntary movement of the tongue, lips, and face unless the patient has concomitant Parkinson's disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition
Infectious Diarrhea
This medicine decreases the elimination of bacteria that cause diarrhea, therefore, not recommended in patients with infectious diarrhea. Inform the doctor if you are having severe diarrhea or received antibiotics before receiving this medicine.
Hypertension
This medicine should be used with caution in patients with hypertension due to the increased risk of high blood pressure. Regular monitoring of blood pressure is necessary while receiving these medicines. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Withdrawal effect
Do not stop taking this medicine without informing the doctor as it may worsen the disease. Gradual dose reduction should be made, and close monitoring of symptoms is necessary.
Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during the treatment with this medicine as it may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine
Atenolol
Clobazam
Bupropion
Citalopram
Clozapine
Amiodarone
Bedaquiline
Ceritinib
Disease interactions
Liver Disease
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Neuroleptic Malignant Syndrome (NMS)
This medicine should be used with extreme caution in patients with a history of neuroleptic malignant syndrome due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Kidney Disease
This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Seizure disorders
This medicine should be used with extreme caution in patients suffering from seizure disorder due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Tardive Dyskinesia
This medicine should be used with extreme caution in patients with a history of Tardive Dyskinesia due to the increased risk of recurrent symptoms. This risk is especially higher in elderly female patients. Report any symptoms such as uncontrolled movements of the tongue, mouth, lips, jaw, hands, feet, etc. to your doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Urinary tract obstruction
This medicine is not recommended for use in patients with urinary tract obstruction diseases as it may worsen the condition. Inform the doctor if you are suffering from any urinary tract obstruction diseases, an alternative treatment option should be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by your doctor. Follow all the labeled instructions while taking this medicine. Ensure that the right quantity of medicine is consumed for the prescribed duration only. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Trifluoperazine and trihexyphenidyl work by inhibiting the release of certain chemical substances in the brain which are responsible for causing the symptoms of schizophrenia and Parkinson's disease.
Legal Status
Classification
Category
Phenothiazine antipsychotics, Anticholinergic antiparkinson agents
Schedule
Schedule H
Trifluoperazine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 14 August 2018]. Available from:
Trihexyphenidyl - DrugBank [Internet]. Drugbank.ca. 2018 [cited 14 August 2018]. Available from:
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Information on this page was last updated on 1 Apr 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
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