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Luprorin 4 Injection
Manufactured byINTAS PHARMACEUTICALS LTD
ContainsLeuprorelin
CURRENTLY UNAVAILABLE
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Description
Luprorin 4 Injection is an anticancer medicine containing Leuprolide. This medicine is used in the treatment of prostate cancer (cancer that occurs in the prostate gland that produces sperm carrying fluid) in men. In women, this medicine treats uterine fibroids (abnormal growth in the uterus) and endometriosis (a condition characterized by abnormal growth of uterine tissue, severe pain, and irregular periods). It is also used to treat the early onset of puberty (the process of physical changes through which a child's body matures into an adult body) in children.
Luprorin 4 Injection may cause some side effects like increased sweating, tiredness, muscular weakness, and hot flashes. Inform your if these side effects are bothering you or persisting for a longer period. Avoid using Luprorin 4 Injection if you are allergic to it.
Luprorin 4 Injection is given by a qualified medical practitioner in the hospital setting. The dose of medicine and the duration of treatment will be decided by your doctor based on your health condition. It may take a few weeks to months to notice desired effects of this medicine.
Luprorin 4 Injection is not recommended for use in children below 2 years of age as no sufficient information is available regarding its safety. Long-term use of Luprorin 4 Injection may result in bone weakness and a decrease in bone mineral density. Your doctor may advise you to take vitamin D and calcium supplements along with this medicine. Luprorin 4 Injection may stop your menstrual cycle for 7- 12 weeks. Consult your doctor if you have noticed any unusual side effects.
Luprorin 4 Injection is not recommended for use if you are pregnant, planning a pregnancy or are breastfeeding. Inform your doctor of your complete medical history including other health conditions you have, before receiving this medicine.
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Substitutes
List of substitutes for Luprorin 4 Injection
Side effects
Major & minor side effects for Luprorin 4 Injection
Dizziness
Headache
Nausea and vomiting
Weight gain
Blurred vision
Sweating
Chest pain or discomfort
Stopping of menstrual periods
Irregular heartbeat
Vaginal discharge and bleeding
Swelling of feet and lower legs
Pelvic pain
Numbness or tingling in the hands or feet
Skin rash
Dryness, burning, or itching of the vagina
Increased hair growth
Uses of Luprorin 4 Injection
What is it prescribed for?
Prostate cancer
Prostate cancer is the abnormal growth of cells in the prostate gland. The prostate is a walnut-shaped gland that produces sperm-carrying fluid in men. This is a serious condition characterized by symptoms like pain in the lower pelvic area, difficulty in urinating, weak urine flow, blood in the urine, painful ejaculation, etc. Luprorin 4 Injection slows or prevents the growth of these cancer cells by lowering testosterone levels in men (sex hormone in males). Thus, this medicine helps in relieving your symptoms.
Endometriosis
Endometriosis is a condition characterized by abnormal growth of tissue that lines the uterus. Symptoms include irregular periods, pain and cramps in the lower abdomen, back pain, diarrhoea, etc. Luprorin 4 Injection works by slowing or preventing the abnormal growth of the uterus lining by lowering the level of estrogen (female sex hormone). This helps in relieving symptoms of endometriosis.
Uterine fibroids
Uterine fibroids are non-cancerous growth of cells that form into lumps in the uterus. Luprorin 4 Injection suppresses the function of the enzyme that causes fibroid growth. As a result, they shrink in size and stop growing further. It also decreases the level of estrogen (hormones that cause females to have periods) and prevents heavy menstrual bleeding.
Central precocious puberty (CPP)
Central precocious puberty (CPP) is a condition in which there is early onset of puberty (the process of physical changes through which a child's body matures into an adult body) in children. Puberty usually begins from the age of 8-14 years. It is characterized by the early development of sexual characteristics and problems with bone growth. Luprorin 4 Injection helps in delaying the early onset of puberty by limiting the production of sex hormones (testosterone in boys and oestrogen in girls). This medicine should only be taken on your doctor’s recommendation.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The onset of action for Luprorin 4 Injection is 4-5 hours after administration.How long do the effects of this medicine last?
The amount of time for which Luprorin 4 Injection remains active in the body is 18 hours.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported for Luprorin 4 Injection.Can this medicine be taken during pregnancy?
Luprorin 4 Injection is not recommended to be used in pregnancy as it may harm your foetus. Inform your doctor if you are pregnant before taking this medicine.Can this medicine be taken while breast-feeding?
Luprorin 4 Injection is not recommended to be used in breastfeeding as it is not known whether this medicine passes into the breastmilk or not. Inform your doctor if you are breastfeeding before taking this medicine.
Allergy
Avoid receiving Luprorin 4 Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Pregnancy
Luprorin 4 Injection is not recommended for use if you are pregnant or planning a pregnancy, because this medicine can harm your foetus.
Warnings for special population
Pregnancy
Luprorin 4 Injection is not recommended to be used in pregnancy as it may harm your foetus. Inform your doctor if you are pregnant before taking this medicine.
Breast-feeding
Luprorin 4 Injection is not recommended to be used in breastfeeding as it is not known whether this medicine passes into the breastmilk or not. Inform your doctor if you are breastfeeding before taking this medicine.
General warnings
Undiagnosed vaginal bleeding
Avoid taking Luprorin 4 Injection if you have a condition of undiagnosed vaginal bleeding as this medicine may worsen your condition.
Depression
Depression is a mental condition in which your mood is unstable. Inform your doctor if you have such a condition before receiving Luprorin 4 Injection as it may worsen your condition.
Bone mineral density
Luprorin 4 Injection can lower bone density, especially if taken over an extended period. While using this medication, notify your doctor if you experience any odd symptoms such as joint discomfort or tenderness.
QT interval prolongation
QT interval prolongation is an irregularity in your heart's electrical activity. Luprorin 4 Injection lowers sex hormone levels, which might cause the ECG's QT interval to lengthen. While taking this prescription, your doctor may recommend tests to monitor your heart's function.
Driving or operating machines
Luprorin 4 Injection may cause dizziness, fatigue, or visual disturbances in some people. Avoid doing activities that require concentration, such as driving vehicles or operating machines if you experience any of these symptoms after taking this medicine.
Birth control measures
Luprorin 4 Injection may reduce the effectiveness of birth control medicines. Use other birth control methods by consulting your doctor to prevent unwanted pregnancy while on treatment with this medicine.
Missed Dose
Luprorin 4 Injection is administered in the hospital or clinical setting by a qualified healthcare professional. Hence, the likelihood of a missed dose is very low.
Overdose
Luprorin 4 Injectionis administered in the hospital or clinical setting by a qualified healthcare professional. Hence, the likelihood of an overdose is very low.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Thalidomide
Efavirenz
Citalopram
Amiodarone
Quinidine
Metformin
Disease interactions
Diabetes mellitus
Diabetes mellitus is a condition in which there is an increase in your blood sugar levels. Luprorin 4 Injection should be used with caution if you have diabetes as it may further increase your blood sugar levels.
Heart disease
Luprorin 4 Injection should be used with caution if you have heart problems as it may cause a heart attack (a blockage of blood flow to the heart muscle) and stroke (brain damage due to interrupted blood flow). Inform your doctor if you have heart conditions before receiving this medicine.
Seizures
A seizure is an electrical disturbance in the brain that occurs spontaneously. Luprorin 4 Injection may worsen seizures (fits) and other mental health conditions. Inform your doctor if you have such conditions before receiving this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Luprorin 4 Injection is used in the treatment of prostate cancer and endometriosis. The pediatric dose of this medicine is used in treating central precocious puberty.
Do not self administer this medicine. It should be administered by a qualified healthcare professional in the hospital setting.
Inform your doctor if you have a known allergy to this medication. Inform your doctor about all your current medications and your medical conditions before taking Luprorin 4 Injection.
Luprorin 4 Injection may cause dizziness or blurred vision. Hence avoid driving vehicles or operating machines after taking this medicine.
Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before receiving this medicine.
Miscelleneous
How it works
Luprorin 4 Injection works by lowering the levels of sex hormones in the body (testosterone in men and estrogen in women). It also stops the production of hormones by the ovaries (female reproductive organs), this leads to a decrease in the level of estrogen (one of the hormones that cause females to have periods).
Legal Status
Classification
Category
Gonadotropin releasing hormones, Hormones/antineoplastics
Schedule
Schedule H
Drugs, H., 2021. Leuprolide Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 8 July 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Leuprorelin. [online] Available at: < [Accessed 8 July 2021].
Rxlist.com. 2021. [online] Available at: < [Accessed 8 July 2021].
Medicines.org.uk. 2021. Prostap SR DCS 3.75 mg Powder and Solvent for Prolonged-release Suspension for Injection in Pre-filled Syringe - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 8 July 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - LEUPROLIDE ACETATE injection, solution. [online] Available at: < [Accessed 8 July 2021].
Information on this page was last updated on 22 Oct 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.