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Liofen 50 MG Injection

Manufactured bySun Pharma Laboratories Ltd.
ContainsBaclofen
CURRENTLY UNAVAILABLE

Description

Liofen 50 MG Injection is a skeletal muscle relaxant that is used for the treatment of severe spasticity (a condition where the muscles are contracted continuously) in various conditions such as multiple sclerosis, spinal cord injuries, or other spinal cord disorders.
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Substitutes

List of substitutes for Liofen 50 MG Injection

Side effects

Major & minor side effects for Liofen 50 MG Injection

Ringing or buzzing in the ears

Change in mood

Skin rash

Confusion

Dizziness

Pain at the injection site

Muscle weakness

Headache

Constipation

Difficult or painful urination

Uses of Liofen 50 MG Injection

What is it prescribed for?

Spasticity

This medicine is used for the treatment of severe spasticity caused due to the brain or spinal cord injury characterized by stiffness of muscles and interferes with normal body movement.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for this medicine to show its action is not clinically established.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    No habit forming tendency has been reported

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to baclofen or any other inactive ingredients present along with the formulation.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

Gastrointestinal disorders

This medicine should be used with caution in patients with gastrointestinal disorders such as peptic ulcer disease, gastrointestinal obstructive disorders, etc. since it may worsen the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney diseases

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Clobazam

Codeine

Cetirizine

Atenolol

Metoclopramide

Disease interactions

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Psychosis

This medicine should be used with caution in patients with psychiatric disorders since it may worsen psychotic symptoms. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizures

This medicine should be used with caution in patients with seizure disorders since it may worsen the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

This medicine works by inhibiting the release of certain chemicals at the spinal level and relieves pain and improves muscle movement.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Skeletal muscle relaxants

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2020 [cited 7 April 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.3267.pdf

[Internet]. Medsafe.govt.nz. 2020 [cited 7 April 2020]. Available from:

https://www.medsafe.govt.nz/Profs/Datasheet/b/baclofeninj.pdf

[Internet]. Accessdata.fda.gov. 2020 [cited 7 April 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020075s021lbl.pdf

Baclofen - DrugBank [Internet]. Drugbank.ca. 2020 [cited 7 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB00181

Lioresal® Intrathecal (baclofen injection) [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 7 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=4e478edb-e340-4976-ac24-4bb32c5e12e3&type=display

Gablofen® (baclofen injection) - US - Piramal Critical Care [Internet]. US - Piramal Critical Care. 2020 [cited 7 April 2020]. Available from:

https://www.piramalcriticalcare.com/us/products/intrathecal/gablofen/

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Information on this page was last updated on 14 Apr 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.