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Itrasig 100 MG Tablet

Manufactured bySignova Pharma Pvt. Ltd.
ContainsItraconazole
CURRENTLY UNAVAILABLE

Description

Itrasig 100 MG Tablet is an antifungal medicine used in the treatment of fungal infections in various parts of your body like the lungs, nails, mouth, throat, etc. It works by preventing the growth of fungi that are responsible for causing the infections. Itrasig 100 MG Tablet may show some side effects such as diarrhoea, nausea, stomach pain, bloating, dizziness, fatigue, headache, menstrual problems, etc. If you notice any allergic reactions like a skin rash, tingling sensation in your arms and legs, difficulty in breathing, or swelling of your face, lips, tongue, or neck, seek emergency medical attention. Itrasig 100 MG Tablet is recommended to be taken with food and plenty of water to ensure maximum absorption. Take it exactly as prescribed by your doctor. Even if your symptoms are relieved after a few days, do not stop taking this medication without consulting your doctor first. Sudden discontinuation may cause your infection to reappear and become resistant to further treatment. Consult your doctor if you do not notice any changes in your condition. Itrasig 100 MG Tablet is not recommended if you have a history of heart failure. Inform your doctor if you have any other medical conditions, or if you are taking any medications. Avoid taking this medicine if you are pregnant, especially in the first trimester as it may cause harm to your foetus. If you are breastfeeding, take this medicine only after your doctor's recommendation.
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Substitutes

List of substitutes for Itrasig 100 MG Tablet

Side effects

Major & minor side effects for Itrasig 100 MG Tablet

Convulsions

Dry mouth

Irregular heartbeat

Increased thirst

Stomach pain

Decreased urine output

Diarrhoea

Dizziness

Nervousness

Weight gain

Unusual bleeding or bruising

Double vision

Uses of Itrasig 100 MG Tablet

What is it prescribed for?

Blastomycosis

Blastomycosis is a fungal infection that can affect your lungs and also other parts of the body such as skin, bones, and joints. This condition is mostly asymptomatic (does not show symptoms) in the early stages, and when the infection becomes severe, it shows symptoms like night sweats, fever, cough, weight loss, chest pain, tiredness, etc. Itrasig 100 MG Tablet slows down the growth of the fungus and prevents it from spreading, thus it helps in treating the condition.

Histoplasmosis

Histoplasmosis is a fungal infection that primarily affects your lungs. This condition may resolve on its own, but you will need treatment if the condition is severe. Itrasig 100 MG Tablet is used to treat this condition by preventing fungal growth.

Invasive Aspergillosis

Invasive Aspergillosis is a fungal infection that mainly affects the lungs and spreads to other body parts like the brain, heart, kidney, and skin. This infection may become life-threatening if you have a compromised immune system (immune system become weak due to certain medicines or medical conditions) or other underlying conditions. Itrasig 100 MG Tablet slows down the spread of the fungus and thus helps in treating the condition.

Onychomycosis

Onychomycosis is a fungal infection in the fingernail and toenail. It is characterized by nail discolouration, ragged or crumbly nails, etc. Itrasig 100 MG Tablet helps prevent the spread of infection by reducing the growth of fungi.

Vulvovaginal Candidiasis

Vulvovaginal candidiasis is a fungal infection in the vagina that causes itching and white discharge. Itrasig 100 MG Tablet helps in treating its symptoms and reduces the growth of the fungus.

Pityriasis versicolor

Pityriasis Versicolor is a fungal infection that affects the skin and leads to small flaky, discoloured patches on your chest and back. Itrasig 100 MG Tablet works by killing fungus and preventing their growth. This relieves the different symptoms caused by the infection and speeds up the healing process.

Dermatophytoses

Dermatophytoses are fungal infections that affect your skin, nails or scalp. Itrasig 100 MG Tablet stops the growth of fungi and helps in treating its symptoms like itchiness and rashes.

Oral candidiasis

Oral candidiasis is a fungal infection that is seen in the mouth. This condition is characterised by white lesions on the tongue and inner cheeks. Itrasig 100 MG Tablet reduces these white lesions by preventing the growth of fungus.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time Itrasig 100 MG Tablet takes to show its action is not known.

  • How long do the effects of this medicine last?

    Itrasig 100 MG Tablet may remain in your body for approximately 6 days.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    Itrasig 100 MG Tablet has no habit-forming tendency.

  • Can this medicine be taken during pregnancy?

    Itrasig 100 MG Tablet is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant or planning a pregnancy.

  • Can this medicine be taken while breast-feeding?

    Itrasig 100 MG Tablet may pass into breast milk in a trace amount. Consult your doctor before taking this medicine.

Allergy

Avoid taking Itrasig 100 MG Tablet if you are allergic to Itraconazole or any other components present in the medicine. Seek immediate medical attention if you have symptoms such as skin rashes, itching/swelling (especially of the face/tongue/lips/throat), shortness of breath, etc.

QT interval prolongation

Itrasig 100 MG Tablet may cause a problem in your heart rhythm called prolonged QT intervals (an electrical heartbeat disturbance), especially if you are taking it along with your heart medications. It may result in fast, rapid, and irregular heartbeats. Consult your doctor for further guidance in such conditions.

Congestive Heart Failure

Avoid taking Itrasig 100 MG Tablet if you have a history of congestive heart failure (a condition in which the heart is unable to pump blood efficiently) or other severe heart conditions as prolonged treatment with this medicine may worsen your condition.

Warnings for special population

Pregnancy

Itrasig 100 MG Tablet is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant or planning a pregnancy.

Breast-feeding

Itrasig 100 MG Tablet may pass into breast milk in a trace amount. Consult your doctor before taking this medicine.

General warnings

Hearing loss

Quinidine is a medicine used to treat irregular heartbeats. The use of Itrasig 100 MG Tablet along with Quinidine may result in temporary or permanent hearing loss. When the treatment is discontinued after your doctor's advice, hearing loss usually resolves, but consult your doctor if it persists.

Neuropathy

Neuropathy is a condition where there is destruction or dysfunction of one or more nerves, resulting in numbness, muscular weakness, tingling, and pain in the affected region. If you experience these symptoms while taking Itrasig 100 MG Tablet, inform your doctor immediately. Discontinue the treatment only on your doctor’s recommendation.

Driving or operating machines

Treatment with Itrasig 100 MG Tablet may cause dizziness, confusion, or disorientation in some cases. Hence, avoid activities such as driving vehicles or operating machines if you experience any of these symptoms.

Immunocompromised individuals

If you have a weak or compromised immunity e.g., in neutropenia (low level of white blood cells), AIDS (acquired immunodeficiency syndrome), or after organ transplantation, Itrasig 100 MG Tablet may not be effective enough to treat the infection. Consult your doctor for further guidance in this regard.

Women of child bearing age

Women of childbearing age should use contraceptive precautions while taking Itrasig 100 MG Tablet. Continue the use of contraceptives until the next menstrual cycle even after stopping the treatment.

Missed Dose

If you forget to take a dose of Itrasig 100 MG Tablet, make sure that you take it as soon as you remember. However, do not take two doses together to make up for a forgotten dose.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Itrasig 100 MG Tablet, seek immediate medical guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Alprazolam

Erythromycin

Warfarin

Atorvastatin

Disease interactions

Liver Disease

Itrasig 100 MG Tablet should be taken with extreme caution if you have liver problems as it is mostly breakdown in the liver. In a rare case, it may result in serious liver toxicity. Your doctor may suggest tests to monitor your liver function regularly during treatment with this medicine.

Achlorhydria

Achlorhydria is a disorder in which your stomach fails to produce hydrochloric acid, a component of the stomach acid that is required for digestion. The absorption of Itrasig 100 MG Tablet decreases when stomach acid is decreased. Take this medicine with caution if you are diagnosed with such conditions.

Food interactions

Take Itrasig 100 MG Tablet with food as it helps to increase absorption from the stomach thereby giving better efficacy.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Itrasig 100 MG Tablet should be taken with food, or as prescribed by your doctor. Do not break, chew, or crush the tablet. Do not exceed the recommended dose. Take the medication at the same time every day. Antacid delays the absorption of this medicine hence, do not take antacids (stomach acid-reducing medicines) within two hours after taking Itrasig 100 MG Tablet. If you notice any side effects that persist or worsen, report them to your doctor as soon as possible. Your doctor may suggest tests to monitor your liver function during treatment with Itrasig 100 MG Tablet. If you observe any of the following symptoms like yellowing of the eyes or skin, black urine, stomach discomfort, etc., inform your doctor.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

Itrasig 100 MG Tablet works by stopping the production of a chemical known as ergosterol, which is responsible for forming the fungal cell membrane (protective covering). Thus by stopping this mechanism, stops the growth and spread of fungal infection.

Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Azole antifungals

Schedule

Schedule H

Drugs, H., 2021. Itraconazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 1 March 2021].

https://medlineplus.gov/druginfo/meds/a692049.html

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 1 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484S000lbl.pdf

Stewart, M., 2021. Itraconazole for fungal infections - Sporanox. [online] Patient.info. Available at: o/medicine/itraconazole-for-fungal-infections-sporanox [Accessed 2 November 2021].

https://patient.inf

2021. [online] Available at: [Accessed 2 November 2021].

https://www.nps.org.au/medicine-finder/apo-itraconazole-capsules

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Information on this page was last updated on 20 Jan 2023

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