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Exemestane
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Description
Exemestane is used in the treatment of early stage breast cancer in postmenopausal women and in women who have already been treated with tamoxifen for 2 to 3 years without much clinical response. Patients with vitamin D deficiency are advised to take vitamin D supplements during treatment with this medicine.
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Side effects
Major & minor side effects for Exemestane
Hypersensitivity
Shortness of breath
Chest pain
Hot flushes
Increased sweating
Mental depression
Bone and joint pain
Trouble sleeping
Swelling of ankles or feet
Difficult or painful urination
Uses of Exemestane
What is it prescribed for?
Breast cancer
This medicine is used in the treatment of early stage breast cancer in postmenopausal women and in women who have been treated with tamoxifen for 2 to 3 years without much clinical response.
Concerns
Commonly asked questions
Onset of action
The amount of time required for this medicine to show its action is not clinically established.Duration of effect
The amount of time for which this medicine remains active in the body is not clinically established.Safe with alcohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is it habit forming?
No habit forming tendencies were reported.Usage in pregnancy?
This medicine is not recommended for use in pregnant women.Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women.
Allergy
This medicine is not recommended for use in patients with a known allergy to exemestane or any other components present along with it.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women.
Breast-feeding
This medicine is not recommended for use in breastfeeding women.
General warnings
Reduction in bone mineral density (BMD)
This medicine may decrease bone mineral density (BMD). The bone mineral density should be assessed prior to initiating the treatment. Routine monitoring of BMD, appropriate corrective measures, or replacement with a suitable alternative may be required based on the clinical condition.
Vitamin D deficiency
Exemestane may cause vitamin D deficiency. The level of 25-hydroxy vitamin D should be assessed prior to initiating the treatment. Routine monitoring of vitamin D levels, appropriate corrective measures, or replacement with a suitable alternative may be required based on the clinical condition.
Co-administration with estrogen containing products
This medicine is not recommended for use along with estrogen containing products since these products may alter the effects of the medicine and vice versa.
Use in premenopausal women
This medicine is not indicated for use in premenopausal women.
Sports
Use of this medicine during sports events is prohibited by World Anti-Doping Agency (WADA).
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Carbamazepine
Phenytoin
Bosentan
Thalidomide
Armodafinil
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Use Exemestane only for the conditions specified by the doctor. Do not take this medicine in larger or smaller amounts than prescribed or share this medicine with others. Report to the doctor all your medical conditions and current medicines including herbs and supplements before starting treatment with this medicine. Report any undesired effects or lack of improvement to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Since Exemestane decreases the amount of estrogen in the body, it slows down or stops the growth of certain specific cancer cells which need estrogen to grow.
Legal Status
Classification
Category
Hormonal antineoplastic agents
Schedule
Schedule H
DailyMed: Exemestane tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 29 August 2017]. Available from:
Exemestane: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 29 August 2017]. Available from:
Exemestane: DrugBank [Internet]. Drugbank.ca. 2017 [cited 29 August 2017]. Available from:
[Internet]. 2017 [cited 29 August 2017]. Available from:
Exemestane [Internet]. Snomedbrowser.com. 2017 [cited 29 August 2017]. Available from:
What is Prohibited [Internet]. World Anti-Doping Agency. 2017 [cited 29 August 2017]. Available from:
Information on this page was last updated on 15 Sep 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.