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Espauz 0.625 mg Tablet

Manufactured byGLENMARK PHARMACEUTICALS LTD
ContainsConjugated Estrogens
CURRENTLY UNAVAILABLE

Description

Espauz 0.625 mg Tablet is a mixture of oestrogen hormones. It is used for the treatment of hormone-mediated diseases like osteoporosis (a condition leading to brittle and fragile bones), some forms of breast cancers, prostate cancer, etc. It is also used to treat the symptoms of menopause (time that marks the end of the menstrual cycle) like hot flashes, vaginal drying, and itching, etc. Espauz 0.625 mg Tablet works by replacing or replenishing the hormone oestrogen that is normally produced in the body. It can cause side effects like headache, body ache, tiredness etc. Most of these are temporary and resolve on their own. Consult your doctor if these side effects are persistent or worsening. Avoid driving vehicles or operating machines after taking this medicine as it can make you feel dizzy. Espauz 0.625 mg Tablet is usually taken with food to avoid stomach irritation. Take this medicine at the same time every day to maintain a constant level of medicine in your body. Do not stop taking this medicine without consulting your doctor as your symptoms may reoccur. Espauz 0.625 mg Tablet is not recommended if you are allergic to it. Inform your doctor all about your current medications and existing medical conditions. This will help your doctor to adjust your dose for avoiding side effects. If you are pregnant or breastfeeding, consult your doctor before using this medicine.
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Substitutes

List of substitutes for Espauz 0.625 mg Tablet

Side effects

Major & minor side effects for Espauz 0.625 mg Tablet

Body aches or pain

Cough

Difficulty in breathing

Headache

Unusual tiredness or weakness

Dark urine

Vaginal discharge

Dizziness

Hair loss

Weight loss or weight gain

Uses of Espauz 0.625 mg Tablet

What is it prescribed for?

Post menopausal symptoms

Menopause is the time that marks the end of your menstrual cycles. It is diagnosed if a duration of 12 months has passed without a menstrual period. Espauz 0.625 mg Tablet is used to relieve and treat the symptoms experienced after menopause, like hot flashes and vaginal dryness.

Female hypogonadism

Female hypogonadism develops when the sex glands produce little or no sex hormones, resulting in reduced functioning of ovaries in females. Espauz 0.625 mg Tablet is used to treat this condition by increasing the level of female sex hormone, i.e. oestrogen.

Palliative treatment of breast and prostate cancer

Palliative care is specialized medical care that focuses on providing relief from pain and other symptoms of a serious illness. Espauz 0.625 mg Tablet is used to provide palliative care for people who have breast or prostate cancer by decreasing pain and other symptoms of cancer.

Primary ovarian failure

Primary ovarian insufficiency (POI), also known as premature ovarian failure, happens when a woman's ovaries stop working normally before 40 years of age. This can result in low estrogen levels and infertility. Espauz 0.625 mg Tablet is used to treat the symptoms of primary ovarian failure by increasing the levels of oestrogen.

Vaginal atrophy

Vaginal atrophy (atrophic vaginitis) is a condition where the lining of the vagina gets drier and thinner due to decreased oestrogen levels. This results in itching, burning and pain during sex, etc. Espauz 0.625 mg Tablet is used in the treatment of this condition by increasing the oestrogen levels in your body.

Postmenopausal osteoporosis

Postmenopausal osteoporosis generally develops after menopause, when oestrogen levels decrease. It is the most common type of osteoporosis. Osteoporosis is a condition that causes your bones to become weak and brittle. Espauz 0.625 mg Tablet is used to prevent and treat the symptoms of osteoporosis in women who have reached menopause.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for Espauz 0.625 mg Tablet to show its action is not clinically established.

  • How long do the effects of this medicine last?

    Espauz 0.625 mg Tablet may remain in your body for four to five days.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Espauz 0.625 mg Tablet.

  • Can this medicine be taken during pregnancy?

    Espauz 0.625 mg Tablet is not recommended if you are pregnant or planning a pregnancy. Contact your doctor if you suspect pregnancy while being treated with this medicine.

  • Can this medicine be taken while breast-feeding?

    Espauz 0.625 mg Tablet is not recommended if you are breastfeeding. Consult your doctor to understand all risks and benefits before taking this medicine.

Allergy

Espauz 0.625 mg Tablet is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Undiagnosed genital bleeding

Espauz 0.625 mg Tablet is not recommended for use if you have an abnormal episode of genital bleeding which was not diagnosed. Taking this medicine in such a case may worsen your condition.

Heart and blood vessel disorder

Espauz 0.625 mg Tablet is not recommended for use if you have/had any condition of heart or blood vessels as it can aggravate such conditions.

Breast cancer

Espauz 0.625 mg Tablet is not recommended for use if you have a history of breast cancer (except for end-stage). It can increase the severity or risk of breast cancer.

Liver Disease

Espauz 0.625 mg Tablet is not recommended for use if you have liver problems. This medicine is broken down and absorbed in the liver. If you have liver problems, this medicine cannot be absorbed and increases the risk of toxicity.

Estrogen-dependent tumor

Espauz 0.625 mg Tablet is not recommended for use if you have an oestrogen-dependent tumour as this medicine increases oestrogen levels in your body which may worsen your condition.

Warnings for special population

Pregnancy

Espauz 0.625 mg Tablet is not recommended if you are pregnant or planning a pregnancy. Contact your doctor if you suspect pregnancy while being treated with this medicine.

Breast-feeding

Espauz 0.625 mg Tablet is not recommended if you are breastfeeding. Consult your doctor to understand all risks and benefits before taking this medicine.

General warnings

Kidney disease

Espauz 0.625 mg Tablet should be used with caution if you have kidney problems as an affected kidney cannot filter the medicine properly. This can increase the risk of toxicity.

Use in children

Espauz 0.625 mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy data of use are not clinically established.

Jaundice like symptoms

Use of Espauz 0.625 mg Tablet can cause yellowing of the eyes and skin due to its effect on the liver and the gall bladder. If you develop such symptoms, inform your doctor immediately.

Driving or operating machinery

Use of Espauz 0.625 mg Tablet may cause blurred vision or dizziness. It is advised that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose of Espauz 0.625 mg Tablet as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment in case of an overdose of Espauz 0.625 mg Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Thalidomide

Efavirenz

Acarbose

Lenalidomide

Carfilzomib

Disease interactions

Hypertension

Espauz 0.625 mg Tablet should be used with extreme caution if you have high blood pressure as this medicine can increase your heart rate and blood pressure. Your doctor may frequently monitor your blood pressure and/or adjust your dose if required.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Espauz 0.625 mg Tablet as instructed by your doctor. Drink plenty of water with it to avoid stomach irritation. Do not break, crush or chew the tablet. Espauz 0.625 mg Tablet is given for a long period. Therefore, do not stop taking this medicine even if you feel better after a few doses. Do not take in larger amounts than prescribed. Consult your doctor if you experience any undesirable effects. It is advised to do regular follow-ups with your doctor while taking this medicine.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Espauz 0.625 mg Tablet works by replacing or replenishing the hormone oestrogen that is normally produced in the body.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Estrogens

Schedule

Schedule H

Medicines.org.uk. 2021. Premarin 0.625 mg Coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 25 November 2021].

https://www.medicines.org.uk/emc/product/2900/smpc>

S3-us-west-2.amazonaws.com. 2021. [online] Available at: < [Accessed 25 November 2021].

https://s3-us-west-2.amazonaws.com/drugbank/fda_labels/DB00286.pdf?1471370910>

Dailymed.nlm.nih.gov. 2021. DailyMed - PREMARIN- conjugated estrogens tablet, film coated. [online] Available at: < [Accessed 25 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1fcd61a8-1a67-4785-a51a-45fca6fbb32b&audience=consumer>

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Information on this page was last updated on 25 Nov 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.