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Enzem Plus Tablet
Manufactured bySAFFRON THERAPEUTICS PVT LTD
ContainsTrypsin (48 mg) + Rutoside (100 mg) + Bromelain (90 mg) + Diclofenac (50 mg)
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Description
Enzem Plus Tablet is a pain-relieving medicine which is a combination of Trypsin, Rutoside, Bromelain and Diclofenac. Enzem Plus Tablet provides effective relief from pain and swelling associated with ankylosing spondylitis (a type of arthritis where the bones of your spinal cord fuse together), osteoarthritis (painful swelling of your joints) and rheumatoid arthritis (a type of arthritis that affects the small joints of your body). It is also used to provide relief from headaches, toothaches, backaches, menstrual pain, ear pain, throat pain, sprains, and strains.
Enzem Plus Tablet shows some common side effects like nausea, vomiting, heartburn, stomach upset, loss of appetite, and diarrhoea. It may cause dizziness and blurred vision. Do not drive or do anything requiring your concentration after taking this medicine. It may change the colour and odour of your stool. This is not harmful but consult your doctor if it bothers you. Avoid Enzem Plus Tablet if you are allergic to it.
Enzem Plus Tablet should be taken with food at around the same time every day. If you missed a dose, take your next dose at the scheduled time. Use Enzem Plus Tablet with extreme caution if you have liver and kidney problems. Enzem Plus Tablet is not recommended for children under 18 years of age, pregnant and breastfeeding women.
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Substitutes
List of substitutes for Enzem Plus Tablet
Side effects
Major & minor side effects for Enzem Plus Tablet
Nausea or vomiting
Heartburn
Skin rash
Dizziness
Diarrhoea
Indigestion
Stomach upset
Loss of appetite
Uses of Enzem Plus Tablet
What is it prescribed for?
Pain and inflammation
Pain and inflammation (swelling) are common conditions that occur as a response of your immune system to protect your body from infection, injury, or disease. Enzem Plus Tablet is used to relieve swelling and pain associated with conditions like back pain, muscle soreness, arthritis-related pain, ear pain, throat pain, sprain, strain, menstrual cramps, injury, toothaches and headaches.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Enzem Plus Tablet provides relief from pain and swelling within 1 to 2 hours.How long do the effects of this medicine last?
The effects of Enzem Plus Tablet lasts for 6 to 8 hours.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended while treatment with Enzem Plus Tablet due to the risk of stomach bleeding.Is this a habit forming medicine?
No habit-forming tendencies were reported for Enzem Plus Tablet.Can this medicine be taken during pregnancy?
Enzem Plus Tablet is not recommended for use during pregnancy due to the risk of serious side effects for your developing foetus.Can this medicine be taken while breast-feeding?
Enzem Plus Tablet is not recommended for use in breastfeeding. Your doctor may prescribe an alternate medicine with the same therapeutic effect if necessary.
Allergy
Avoid taking Enzem Plus Tablet if you are allergic to it. Allergic reactions to this medicine are rare. Seek immediate medical attention if you notice any symptoms like a skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Gastrointestinal bleeding
Enzem Plus Tablet may cause stomach and intestinal bleeding and ulcers. Therefore it is not recommended for use in patients with perforation disorders (ex: appendicitis, ulcers, gall bladder disease, etc.) and acidity since it may worsen the condition.
Coronary Artery Bypass Surgery (CABG)
Do not use Enzem Plus Tablet for relieving pain after heart surgery.
Warnings for special population
Pregnancy
Enzem Plus Tablet is not recommended for use during pregnancy due to the risk of serious side effects for your developing foetus.
Breast-feeding
Enzem Plus Tablet is not recommended for use in breastfeeding. Your doctor may prescribe an alternate medicine with the same therapeutic effect if necessary.
General warnings
Skin allergies
Enzem Plus Tablet may cause serious skin allergies. These events may be severe in rare cases. If you develop signs and symptoms like rashes, hives (painful eruptions that sting and itch) or other allergic symptoms should be reported to your doctor immediately. Do not discontinue the treatment without talking to your doctor.
Change in the colour of stools
Enzem Plus Tablet may change the colour and odour of your stools. This is normal and does not harm you.
Driving or operating machinery
Enzem Plus Tablet may rarely cause dizziness, blurred vision, or drowsiness. Do not perform activities such as driving vehicles or operating machines if you experience any of these symptoms.
Use in children
Enzem Plus Tablet is not recommended for use in children below 18 years of age because safety and efficacy data is not available.
Missed Dose
If you miss to take a scheduled dose of Enzem Plus Tablet take it as soon as you remember. If it is almost time for your next dose skip the missed one. Do not double your dose to make up for the missed dose.
Overdose
Never take more than the prescribed dose of Enzem Plus Tablet. Seek emergency medical attention if you suspect that you might have taken an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended while treatment with Enzem Plus Tablet due to the risk of stomach bleeding.
Interaction with Medicine
Ramipril
Digoxin
Warfarin
Disease interactions
Asthma
Patients with asthma may experience allergic reactions while taking Enzem Plus Tablet. It is not recommended for use if you have asthma, as it can trigger asthmatic episodes.
Kidney diseases
Long term use of high doses of Enzem Plus Tablet may cause kidney problems, such as painful urination and proteins or blood in the urine. You should use Enzem Plus Tablet with caution if you have kidney problems. Your doctor will suggest tests to closely monitor your kidney function.
Heart disease
Long-term use of Enzem Plus Tablet may increase the risk of a heart attack, especially if you have any pre-existing heart conditions. It is not recommended for treating pain after coronary bypass surgery.
Liver Disease
Enzem Plus Tablet should be used with caution if you have liver troubles, as it may increase the risk of liver failure.
Gastro-Intestinal toxicity
Long term use of Enzem Plus Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall can occur. Any symptom like indigestion, the appearance of coffee coloured dry blood in stools or vomiting of blood should be reported immediately.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Enzem Plus Tablet with or without food. Never take more than the prescribed dose of this medicine.
Do not give Enzem Plus Tablet to other people even if their condition appears to be the same as yours.
Enzem Plus Tablet may cause an increase in the symptom severity at the start of treatment. However, continue using it as prescribed by your doctor.
Do not drive or do any activity requiring concentration until you know how Enzem Plus Tablet affects you.
Miscelleneous
How it works
Trypsin and Bromelain are enzymes that help in the breakdown of proteins involved in swelling and pain. Rutoside is an antioxidant that protects your body from damage by chemicals that cause swelling. Diclofenac stops the release of chemicals (prostaglandins) in your brain, that increase pain and swelling. Thus, Enzem Plus Tablet provide relief from your aches and swelling.
Legal Status
Classification
Category
Nonsteroidal anti-inflammatory agents, Proteolytic enzyme, Analgesics, Anti-inflammatory agents
Schedule
Schedule H
Pubchem.ncbi.nlm.nih.gov. 2021. Bromelain. [online] Available at: < [Accessed 20 April 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Diclofenac. [online] Available at: < [Accessed 17 May 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Trypsin. [online] Available at: < [Accessed 29 July 2021].
Jcdr.net. 2021. JCDR - Efficacy of Bromelain along with Trypsin, Rutoside Trihydrate enzymes and Diclofenac Sodium Combination Therapy for the treatment of TMJ Osteoarthritis - A Randomised Clinical Trial. [online] Available at: < [Accessed 11 August 2021].
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Information on this page was last updated on 31 Aug 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.