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Endor Plus Eye Drops

Manufactured byENTOD PHARMACEUTICALS LTD
ContainsDorzolamide (2 %w/v) + Timolol (0.5 %w/v)
CURRENTLY UNAVAILABLE

Description

Endor Plus Eye Drops is a combination of Dorzolamide and Timolol. It is used to treat open-angle glaucoma (an eye condition caused due to an abnormal drainage system in the eye causing increased fluid pressure within the eyes) and intraocular hypertension (abnormally high pressure within the eyes). It works by decreasing the pressure in the eye by reducing the amount of fluid within the eyes. Endor Plus Eye Drops shows common side effects such as burning or stinging sensation in your eye, mild eye discomfort, or bitterness in the mouth. These side effects usually subside with time. However, if they persist or become worse, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines immediately after using this medicine, as it can cause blurred vision. Endor Plus Eye Drops should be instilled as directed by your doctor. Wash your hand thoroughly before instilling the eye drop. Avoid using more than the recommended dose. Remove your contact lenses before instilling this medicine in your eyes, and wait for at least 15 to 20 minutes before putting them back in your eyes. Do not touch the tip of the bottle to avoid any contamination. If you are using any other eye drops, maintain a time gap of ten minutes between the administration of both medications. Endor Plus Eye Drops is not recommended if you are allergic to it or have asthma/COPD (respiratory conditions that cause narrowing of the airways making it difficult to breathe), severe kidney problems, or heart-related conditions such as slow or irregular heartbeat or heart failure (the heart works less efficiently than normal). It should be used with caution if you have liver conditions, blood-related problems, or porphyria (a hereditary disorder that may cause nerve and skin problems). Endor Plus Eye Drops is not recommended for use in children less than two years of age. Consult your doctor before using the eye drop if you are pregnant or breastfeeding.

Substitutes

List of substitutes for Endor Plus Eye Drops

Side effects

Major & minor side effects for Endor Plus Eye Drops

Blurred vision

Headache

Increase in blood pressure

Dizziness

Stinging, burning, or discomfort in the eye

Sensitivity to light

Bitter taste

Itching eyes

Redness of the eye

Watery eyes

Swelling of eyes

Uses of Endor Plus Eye Drops

What is it prescribed for?

Intraocular hypertension

Intraocular hypertension is a condition that leads to abnormally high pressure within the eyes. Endor Plus Eye Drops treats the condition by reducing fluid pressure inside the eyes.

Open angle Glaucoma

Open-angle Glaucoma is an eye condition that occurs due to an abnormality in the drainage system of the eye leading to increased fluid pressure within the eye. It may cause optic nerve (a nerve at the back of your eye) damage, reduced vision, and even blindness. Endor Plus Eye Drops treats the condition by reducing the fluid accumulation within the eyes.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Endor Plus Eye Drops can be observed within 20 to 30 minutes.
  • How long do the effects of this medicine last?

    The time duration for which Endor Plus Eye Drops remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Endor Plus Eye Drops.
  • Can this medicine be taken during pregnancy?

    Animal studies indicate that Endor Plus Eye Drops may harm the developing foetus. However, due to the lack of human studies, this medicine should be used in pregnancy only after consulting your doctor.
  • Can this medicine be taken while breast-feeding?

    It is unknown if Endor Plus Eye Drops passes into breastmilk or not. Hence, consult your doctor before using this medicine if you are breastfeeding.

Allergy

Avoid using Endor Plus Eye Drops if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), difficulty in breathing, etc.

Respiratory diseases

Endor Plus Eye Drops is not recommended for use if you have respiratory conditions such as asthma (narrowing of the airways) or severe chronic obstructive pulmonary disease (lung conditions that cause blockage of airflow leading to breathing-related problems). This medicine may get absorbed into the blood and cause bronchoconstriction (narrowing of the airways). Hence, it may worsen your condition.

Heart diseases

Endor Plus Eye Drops is not recommended if you have heart conditions such as sinus bradycardia (slow heartbeat), heart block (when the electrical signal that controls your heartbeat is partially or completely blocked causing slow or irregular heartbeat), cardiogenic shock (the heart suddenly fails to pump the required blood throughout the body), congestive heart failure (heart works less efficiently than normal), as it can make your heart problems worse.

Severe kidney disease

Endor Plus Eye Drops is not recommended for use if you have severe kidney problems as it may further worsen your condition.

Warnings for special population

Pregnancy

Animal studies indicate that Endor Plus Eye Drops may harm the developing foetus. However, due to the lack of human studies, this medicine should be used in pregnancy only after consulting your doctor.

Breast-feeding

It is unknown if Endor Plus Eye Drops passes into breastmilk or not. Hence, consult your doctor before using this medicine if you are breastfeeding.

General warnings

Driving vehicles or operating machines

Avoid driving vehicles or operating machines immediately after using Endor Plus Eye Drops, as it may cause blurred vision.

Liver disease

Endor Plus Eye Drops should be used cautiously if you have liver problems as it may worsen your condition. Follow all the instructions given by your doctor.

Kidney disease

Endor Plus Eye Drops should be used cautiously if you have kidney problems due to the increased risk of side effects. Your doctor may suggest tests to monitor your kidney function during long-term treatment (more than two weeks) of this medicine.

Corneal oedema

Endor Plus Eye Drops should be used cautiously as it may increase the risk of corneal oedema (swelling in the outermost layer of your eyes).

Contact lenses

Use of Endor Plus Eye Drops should be avoided if you are wearing contact lenses in your eyes. The lenses should be removed prior to administration of the eye drop and can be reinserted 15 minutes post-administration.

Contamination

Appropriate precautions should be taken to prevent the contamination of the container. Do not touch the tip of the container against your eye or any other surfaces. Also,close the cap tightly after use.

Use in children

Endor Plus Eye Drops is not recommended for use in children below two years of age.

Missed Dose

In case you miss a dose of Endor Plus Eye Drops, instill it as soon as your remember. However, skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

Do not instill more than the recommended dose of Endor Plus Eye Drops. Consult your doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Aspirin

Epinephrine

Clonidine

Bismuth subsalicylate

Disease interactions

Diabetes

Diabetes refers to high blood sugar levels. Endor Plus Eye Drops should be used with caution if you have diabetes as it may alter blood sugar levels in the body. Follow all the instructions given by your doctor while using this medicine.

Hyperthyroidism

Hyperthyroidism is a condition that occurs due to excess thyroid hormone (a chemical substance that regulates the body's metabolism, digestive function, brain development, bone maintenance, etc.) levels in the body. Endor Plus Eye Drops should be used with caution if you have hyperthyroidism as it can worsen your condition. Avoid discontinuing this medicine without consulting your doctor.

Bone marrow suppression

Endor Plus Eye Drops may cause an alteration in blood cell counts. Hence it should be used with caution if you have bone marrow suppression (the body produces a significantly low amount of blood cells) or other blood disorders.

Porphyria

Endor Plus Eye Drops should be used cautiously if you have porphyria (a hereditary condition resulting in abnormal metabolism of the oxygen-carrying substance in your body i.e haemoglobin). Follow all the instructions given by your doctor in such a condition.

Food interactions

Information not available.

Lab interactions

Information not available.
Endor Plus Eye Drops should be instilled as directed by your doctor. Avoid using more or less than the recommended dose. Pull down your lower eyelid to create a pocket-like shape and squeeze a drop into the pocket. Keep your eyes closed for one or two minutes. Wash your hand thoroughly before instilling the eye drop. Do not touch the tip of the bottle to prevent contamination. Remove the contact lenses before instilling the eye drop, and insert them back 15 to 20 minutes post-administration. If you are using any other eye drops, maintain a time gap of at least ten minutes between two doses. Endor Plus Eye Drops should be used cautiously as it may increase the risk of corneal oedema (swelling in the outermost layer of your eyes). Avoid using Endor Plus Eye Drops if the solution is cloudy or the colour has changed. Take appropriate precautions to prevent contamination of the container. Avoid touching the tip of the bottle against your eye or other surfaces. Also, avoid wiping or rinsing the dropper tip, and close the cover tightly after use.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

Endor Plus Eye Drops works by reducing the fluid pressure inside the eyes.

Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Ophthalmic glaucoma agents

Schedule

Schedule H

Drugs, H., 2022. Dorzolamide and Timolol Ophthalmic: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 4 July 2022].

https://medlineplus.gov/druginfo/meds/a602022.html

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 12 July 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020869s036lbl.pdf

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Information on this page was last updated on 1 Aug 2022

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