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Dyamide Plus 20 Tablet

Manufactured byMACLEODS PHARMACEUTICALS PVT LTD
ContainsSpironolactone (50 mg) + Torsemide (20 mg)
CURRENTLY UNAVAILABLE

Description

Dyamide Plus 20 Tablet is a combination medicine used in the treatment of resistant edema associated with secondary hyperaldosteronism, resistant hypertension, nephrotic syndrome, chronic cardiac failure, and hepatic cirrhosis. This medicine is not recommended for use in patients below 18 years of age.
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Substitutes

List of substitutes for Dyamide Plus 20 Tablet

Side effects

Major & minor side effects for Dyamide Plus 20 Tablet

Stomach pain

Dizziness

Irregular heartbeat

Headache

Skin rash

Breast enlargement in men

Leg cramps

Nausea and Vomiting

Chest pain

Diarrhea

Dry mouth

Loss of appetite

Muscle pain

Sleeplessness

Excessive urination

Constipation

Uses of Dyamide Plus 20 Tablet

What is it prescribed for?

Resistant edema associated with secondary Hyperaldosteronism

This medicine is used in the treatment of resistant edema associated with secondary hyperaldosteronism, a condition where aldosterone is produced excessively due to reduced blood flow to the kidneys.

Congestive Heart Failure

This medicine is used in the treatment of congestive heart failure by preventing water reabsorption.

Resistant Hypertension

This medicine is used in the treatment of resistant hypertension, a condition where the blood pressure remains above 140/90 mmHg despite the concurrent use of three antihypertensive agents of different classes, one of which should be a diuretic.

Hepatic cirrhosis

This medicine is used in the symptomatic treatment of hepatic cirrhosis, a condition characterized by jaundice, ascites, weight loss, swelling of legs, easy bleeding or bruising, etc.

Nephrotic Syndrome

This medicine is used in the symptomatic treatment of nephrotic syndrome, which is a kidney disorder characterized by weight gain due to excess fluid retention, severe swelling around your eyes, ankles, and feet, etc.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of this medicine can be observed within 1 hour of administration of the dose.

  • How long do the effects of this medicine last?

    The effect of this medicine lasts for an average duration of 2 to 3 days.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to spironolactone, torsemide, or any other inactive ingredients present in the formulation.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.

Acute kidney failure

This medicine is not recommended for use in patients with acute kidney failure or impaired kidney function due to the increased risk of worsening of the patient's condition.

Hepatic coma

This medicine is not recommended for use in patients with hepatic coma due to the increased risk of worsening of the patient's condition.

Hypotension

This medicine is not recommended for use in patients with low blood pressure (hypotension) condition, due to the increased risk of worsening of the patient's condition.

Eplerenone

This medicine is not recommended for use in patients who are concomitantly taking eplerenone due to the increased risk of worsening of the patient's condition.

Adrenal insufficiency (Addison's disease)

This medicine is not recommended for use in patients who are suffering from adrenal insufficiency due to the increased risk of worsening of the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Diabetes

This medicine should be used with extreme caution in patients with diabetes mellitus due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Volume depletion and Electrolyte imbalance

This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Use in elderly patients

This medicine should be used with caution in elderly patients due to the increased risk of severe adverse effects. Appropriate dose adjustments may be necessary based on the clinical condition.

Hearing problem

Use of this medicine may increase the risk of developing a hearing problem in some patients. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Metformin

Nonsteroidal anti-inflammatory drugs

Aminoglycoside antibiotics

Angiotensin converting enzyme inhibitors (ACEI's)

Lithium

Disease interactions

Electrolyte imbalance

This medicine should be used with caution in patients prone to electrolyte imbalances since it may worsen the patient's condition. Close monitoring of electrolyte levels is recommended for such patients. Any electrolyte imbalances should be corrected before initiating therapy. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Impaired kidney function

This medicine is not recommended for use in patients with a known history of kidney diseases due to the increased risk of worsening of the patient's condition. Kidney function should be assessed before initiating treatment. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

This medicine should be used with extreme caution in patients with liver impairment due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as advised by your doctor. Do not take in larger amounts than prescribed. It is advised to take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Close monitoring of kidney function and electrolytes levels is necessary during treatment with this medicine. Report any undesired side effects to the doctor. Do not stop the use of this medicine without consulting your doctor.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Spironolactone and Torsemide both increase the excretion of water and sodium through the urine by preventing their reabsorption in the kidneys. Their combination is thus effective in reducing blood pressure, edema, and the strain on the heart.

Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Loop diuretics, Potassium sparing diuretics, Antihypertensive combinations

Schedule

Schedule H

DYTOR PLUS Tablets [Internet]. CiplaMed. 2019 [cited 29 March 2019]. Available from:

https://ciplamed.com/content/dytor-plus-tablets

DailyMed - Spironolactone tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 5 June 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a7510768-8a52-4230-6aa0-b0d92d82588f

[Internet]. 2017 [cited 5 June 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/27264

Torsemide Oral: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 23 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601212.html

[Internet]. Dailymed.nlm.nih.gov. 2017 [cited 23 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cf288ad5-d4e7-4b0b-bfd0-41c5327e6984

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Information on this page was last updated on 5 Apr 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.