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Diplene-Af 0.05% Cream

Manufactured byFulford (India) Ltd.
ContainsClobetasol
CURRENTLY UNAVAILABLE

Description

Diplene-Af 0.05% Cream is topical medicine used to treat skin conditions such as eczema (skin becomes dry, itchy, red, and bumpy), dermatitis (skin irritation), psoriasis (a skin condition that occurs due to abnormal immune activity and causes dry, itchy, and scaly skin due to buildup of skin cells), etc. This medicine works by decreasing the production of certain chemicals in your body. Thus, it reduces redness and swelling on your skin. Diplene-Af 0.05% Cream may cause side effects like burning sensation, itching, and redness at the site of application. These symptoms may last only for a few days and disappear with time as your body adjusts to the medicine. However, consult your doctor if these side effects do not subside with time or worsen. Diplene-Af 0.05% Cream is meant for external use only. Do not use this medicine for more than the prescribed duration. Clean the affected area and pat dry before applying Diplene-Af 0.05% Cream. Apply a thin layer of the cream to the affected area and spread it evenly. Avoid direct contact with your eyes and mouth. Wash immediately with water in case of accidental contact. Diplene-Af 0.05% Cream should be avoided if you are allergic to it. Inform your doctor if you have any other skin conditions or using any other topical medicines. Consult your doctor if you are pregnant or are breastfeeding before using this medicine.
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Substitutes

List of substitutes for Diplene-Af 0.05% Cream

Clobetagen 0.05% Cream
Alkem Laboratories Ltd.
Clobetol 0.05% Cream
Ranbaxy Laboratories Ltd.
Clostar 0.05% Cream
Mankind Pharmaceuticals Ltd.
Soltop 0.05% Cream
Ipca Laboratories Pvt. Ltd.
Tenovate 0.05% Cream
Glaxosmithkline Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Diplene-Af 0.05% Cream

Burning sensation at the application site

Dry skin

Redness of skin

Itching of skin

Uses of Diplene-Af 0.05% Cream

What is it prescribed for?

Steroid responsive skin conditions

Steroids are a class of medicine that is effective in treating skin conditions like eczema (skin gets swollen, cracked, itchy, and red), dermatitis (skin irritation), psoriasis (a skin condition that occurs due to abnormal immune activity causing red, itchy, and scaly patches), Lichen planus (itchy, bumpy, pink or purple rash on the arms and legs), etc. Diplene-Af 0.05% Cream is used in the treatment of such skin conditions.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time required for Diplene-Af 0.05% Cream to show its action is not clinically established.

  • How long do the effects of this medicine last?

    The amount of time for which Diplene-Af 0.05% Cream remains active in your body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Diplene-Af 0.05% Cream.

  • Can this medicine be taken during pregnancy?

    Due to the lack of sufficient safety data, Diplene-Af 0.05% Cream is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

  • Can this medicine be taken while breast-feeding?

    It is not known if Diplene-Af 0.05% Cream passes into breastmilk. Hence, if you are breastfeeding, consult your doctor to understand the potential risks and benefits before using this medicine. If your doctor has recommended this medicine, avoid applying it to the breast area to prevent accidental ingestion by your baby.

Allergy

Avoid using Diplene-Af 0.05% Cream if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Warnings for special population

Pregnancy

Due to the lack of sufficient safety data, Diplene-Af 0.05% Cream is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

Breast-feeding

It is not known if Diplene-Af 0.05% Cream passes into breastmilk. Hence, if you are breastfeeding, consult your doctor to understand the potential risks and benefits before using this medicine. If your doctor has recommended this medicine, avoid applying it to the breast area to prevent accidental ingestion by your baby.

General warnings

Use in children

Diplene-Af 0.05% Cream is not recommended for use in children below 12 years of age as the safety and efficacy data are not clinically established.

External use

Diplene-Af 0.05% Cream is recommended for external use only. Avoid contact with the eyes, mouth, wounds, or broken skin.

Other medicines

Diplene-Af 0.05% Cream may interact with other topical medicines if applied at the same time. Hence consult your doctor before using other topical medicines over this cream.

Missed Dose

Apply the missed dose of Diplene-Af 0.05% Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Diplene-Af 0.05% Cream is not likely to cause severe symptoms unless it is applied for a prolonged period in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

Infections

Prolonged use of a high dose of Diplene-Af 0.05% Cream may get absorbed into the bloodstream and suppress the activity of your immune system. Hence, this medicine should be used with caution as it may increase the risk of infections or worsen your condition if you have an infection.

Hyperadrenocorticism

Hyperadrenocorticism is a condition that occurs due to high levels of cortisol (a chemical substance that helps your body respond to stress, regulate blood sugar, and fight infections) in the body. Diplene-Af 0.05% Cream should be used with caution as it may occasionally cause or worsen hyperadrenocorticism if applied over a large area for a prolonged time.

Ocular Toxicities

Rarely, Diplene-Af 0.05% Cream may increase the intraocular pressure (high pressure inside the eye caused by an imbalance in the production and drainage of fluid in the eye) and cause glaucoma (a condition where the pressure within the eyeballs is abnormally high that can damage the optic nerve and lead to loss of vision). Inform your doctor if you experience any vision problems.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin film of Diplene-Af 0.05% Cream to the affected areas of the skin as instructed by your doctor. Follow all the usage instructions mentioned on the label or the package insert. Avoid applying Diplene-Af 0.05% Cream in larger or smaller quantities than recommended. Avoid covering the application area with bandages or other dressings unless specifically instructed by your doctor. Contact your doctor if the symptoms do not improve or resolve after two weeks of use.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

Diplene-Af 0.05% Cream inhibits the production of certain chemicals in your body and reduces swelling, itching, and redness on your skin.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Topical steroids

Schedule

Schedule H

Drugs, H., 2021. Clobetasol Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 30 March 2021].

https://medlineplus.gov/druginfo/meds/a686008.html

Medicines.org.uk. 2021. Dermovate Cream - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 30 March 2021].

https://www.medicines.org.uk/emc/product/939/smpc

Dailymed.nlm.nih.gov. 2021. DailyMed - TEMOVATE- clobetasol propionate creamTEMOVATE- clobetasol propionate ointment. [online] Available at: [Accessed 30 March 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acecf5ab-dd5e-4046-ab47-b9ff415d4b2b

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 30 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021535s002lbl.pdf

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Information on this page was last updated on 17 Oct 2022

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