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Dihydralazine

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Description

Dihydralazine is used for the treatment of a moderate to severe high blood pressure. It may also be used in a combination with other medicines to manage congestive heart failure. Your doctor may also prescribe this medicine for the treatment of high blood pressure in certain specific circumstances such as a high blood pressure associated with kidney impairment, pregnancy, etc.

Side effects

Major & minor side effects for Dihydralazine

Chest tightness

Nausea

Fast/irregular heart beat

Blurred vision

Skin rash and itching

Dizziness and fainting

Sudden swelling of eyelids, face, throat, tongue

Loss of appetite

Weight loss

Increased thirst

Blistering and peeling of skin

Increased urination

Uses of Dihydralazine

What is it prescribed for?

Hypertension

This medicine is used for the treatment of a high blood pressure which may be caused by genetic or environmental factors. It may also be prescribed for a high blood pressure associated with pregnancy, kidney impairment, etc. in certain specific circumstances.

Congestive Heart Failure

This medicine may also be used in a combination with other medicines for the treatment of congestive heart failure, a condition where the heart is unable to pump blood adequately.
Concerns

Commonly asked questions

  • Onset of action

    The effect of this medicine can be observed within 30 minutes of administration.
  • Duration of effect

    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?

    No habit-forming tendencies were reported.
  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to dihydralazine or any other inactive ingredients present in the formulation.

Severe Tachycardia

This medicine is not recommended for use in patients suffering from severe tachycardia since the risk of side effects is significantly higher.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you report the use of all your current medicines, including any herbs and supplements, to the doctor before beginning therapy with this medicine.

Dizziness and fainting

Use of this medicine may cause dizziness and fainting in some patients. It is advised that you do not perform any activities such as driving vehicles or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Kidney impairment

This medicine should be used with caution in patients with an impairment of normal kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients with an impairment of normal liver function due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Heart and blood vessel disorders

This medicine should be used with extreme caution in patients with a pre-existing condition of the heart or the blood vessels such as ischemic heart disease, myocardial infarction, etc. since it may worsen the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the patient's clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Chlorothiazide

Aliskiren

Phenobarbital

Ciprofloxacin

Methyldopa

Carbamazepine

Rifampicin

Ibuprofen

Diclofenac

Aspirin

Disease interactions

Valvular Heart Disease

This medicine is not recommended for use in patients suffering from valvular heart diseases due to the increased risk of severe or life-threatening adverse effects.

Food interactions

Information not available.

Lab interactions

Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take it in larger or smaller quantities than prescribed. Report any undesired side effects to the doctor. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

This medicine relaxes and dilates the blood vessels, allowing for improved circulation of blood and reducing the blood pressure.

Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Vasodilators

Schedule

Schedule H

Dihydralazine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 24 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/dihydralazine

Dihydralazine - an overview | ScienceDirect Topics [Internet]. Sciencedirect.com. 2018 [cited 24 September 2018]. Available from:

https://www.sciencedirect.com/topics/neuroscience/dihydralazine

Dihydralazine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 24 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB12945
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Information on this page was last updated on 27 Sep 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.